(23 nodes) Mixed, incl. Rho (Ras homology) subfamily of Ras-like small GTPases, and G alpha (12/13) signalling events network (Salpingoeca rosetta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTSG_00107	Protein kinase domain-containing protein. (180 aa)
	PTSG_00306	ARHA protein. (191 aa)
	PTSG_00831	Uncharacterized protein. (642 aa)
	PTSG_01477	Non-specific serine/threonine protein kinase. (503 aa)
	PTSG_02542	SH3 domain-containing protein. (391 aa)
	PTSG_02104	Uncharacterized protein. (183 aa)
	PTSG_11992	Uncharacterized protein. (362 aa)
	PTSG_03696	Uncharacterized protein. (1495 aa)
	PTSG_04167	Uncharacterized protein. (189 aa)
	PTSG_05517	DH domain-containing protein. (378 aa)
	PTSG_05878	Uncharacterized protein. (463 aa)
	PTSG_06029	Serine/threonine protein kinase. (302 aa)
	PTSG_06036	Uncharacterized protein. (494 aa)
	PTSG_06733	Rac GTPase. (191 aa)
	PTSG_06902	Uncharacterized protein. (696 aa)
	PTSG_06685	Rho1 GTPase. (193 aa)
	PTSG_08756	Uncharacterized protein. (799 aa)
	PTSG_08994	Rho-GAP domain-containing protein. (676 aa)
	PTSG_09015	Uncharacterized protein. (1625 aa)
	PTSG_10198	Uncharacterized protein. (192 aa)
	PTSG_10315	Uncharacterized protein. (1406 aa)
	PTSG_11002	Rho-GAP domain-containing protein. (560 aa)
	PTSG_13212	ANK_REP_REGION domain-containing protein. (317 aa)

Your Current Organism:

Salpingoeca rosetta

NCBI taxonomy Id: 946362
Other names: Proterospongia sp. ATCC 50818, S. rosetta, Salpingoeca rosetta ATCC 50818, Salpingoeca rosetta ATCC50818, Salpingoeca rosetta Dayel et al. 2011, Salpingoeca sp. ATCC 50818, Salpingoeca sp. ATCC50818

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PTSG_00107	PTSG_00306	F2TVJ6	F2TW39	Protein kinase domain-containing protein.	ARHA protein.	0.684
PTSG_00107	PTSG_00831	F2TVJ6	F2TXL5	Protein kinase domain-containing protein.	Uncharacterized protein.	0.667
PTSG_00107	PTSG_02104	F2TVJ6	F2U2N0	Protein kinase domain-containing protein.	Uncharacterized protein.	0.401
PTSG_00107	PTSG_02542	F2TVJ6	F2U2H6	Protein kinase domain-containing protein.	SH3 domain-containing protein.	0.708
PTSG_00107	PTSG_05517	F2TVJ6	F2UBF7	Protein kinase domain-containing protein.	DH domain-containing protein.	0.708
PTSG_00107	PTSG_06036	F2TVJ6	F2UDH7	Protein kinase domain-containing protein.	Uncharacterized protein.	0.538
PTSG_00107	PTSG_06685	F2TVJ6	F2UFQ0	Protein kinase domain-containing protein.	Rho1 GTPase.	0.684
PTSG_00107	PTSG_06733	F2TVJ6	F2UEM7	Protein kinase domain-containing protein.	Rac GTPase.	0.684
PTSG_00107	PTSG_06902	F2TVJ6	F2UF48	Protein kinase domain-containing protein.	Uncharacterized protein.	0.719
PTSG_00107	PTSG_09015	F2TVJ6	F2ULY8	Protein kinase domain-containing protein.	Uncharacterized protein.	0.610
PTSG_00107	PTSG_10198	F2TVJ6	F2UQL1	Protein kinase domain-containing protein.	Uncharacterized protein.	0.684
PTSG_00107	PTSG_11002	F2TVJ6	F2USF0	Protein kinase domain-containing protein.	Rho-GAP domain-containing protein.	0.598
PTSG_00107	PTSG_11992	F2TVJ6	F2U4R8	Protein kinase domain-containing protein.	Uncharacterized protein.	0.667
PTSG_00107	PTSG_13212	F2TVJ6	F2UTJ0	Protein kinase domain-containing protein.	ANK_REP_REGION domain-containing protein.	0.650
PTSG_00306	PTSG_00107	F2TW39	F2TVJ6	ARHA protein.	Protein kinase domain-containing protein.	0.684
PTSG_00306	PTSG_00831	F2TW39	F2TXL5	ARHA protein.	Uncharacterized protein.	0.999
PTSG_00306	PTSG_01477	F2TW39	F2U0G3	ARHA protein.	Non-specific serine/threonine protein kinase.	0.899
PTSG_00306	PTSG_02104	F2TW39	F2U2N0	ARHA protein.	Uncharacterized protein.	0.443
PTSG_00306	PTSG_02542	F2TW39	F2U2H6	ARHA protein.	SH3 domain-containing protein.	0.570
PTSG_00306	PTSG_03696	F2TW39	F2U6B8	ARHA protein.	Uncharacterized protein.	0.706

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