(40 nodes) Mixed, incl. Clathrin binding, and Adaptor protein complex, sigma subunit network (Salpingoeca rosetta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTSG_00833	Uncharacterized protein. (524 aa)
	PTSG_01865	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (120 aa)
	PTSG_01942	Uncharacterized protein. (771 aa)
	PTSG_01962	NAK/GAK protein kinase. (307 aa)
	PTSG_01983	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (440 aa)
	PTSG_02431	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
	PTSG_02457	50S ribosomal protein L27. (134 aa)
	PTSG_02537	Sortilin. (1038 aa)
	PTSG_02883	ENTH domain-containing protein. (294 aa)
	PTSG_02909	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1667 aa)
	PTSG_03370	Uncharacterized protein. (230 aa)
	PTSG_03408	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	PTSG_03775	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (416 aa)
	PTSG_03783	Uncharacterized protein. (891 aa)
	PTSG_03662	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (575 aa)
	PTSG_12113	AP4E_app_platf domain-containing protein. (1283 aa)
	PTSG_12118	ENTH domain-containing protein. (374 aa)
	PTSG_04634	AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (608 aa)
	PTSG_04720	NYN domain-containing protein. (615 aa)
	PTSG_05451	Adaptin_N domain-containing protein. (1325 aa)
	PTSG_06413	Sortilin. (1168 aa)
	PTSG_06130	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (798 aa)
	PTSG_06133	Uncharacterized protein. (218 aa)
	PTSG_06947	DUF1681 domain-containing protein. (272 aa)
	PTSG_06511	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (147 aa)
	PTSG_07711	ENTH domain-containing protein. (628 aa)
	PTSG_08387	BTB_2 domain-containing protein. (634 aa)
	PTSG_08421	Coatomer. (871 aa)
	PTSG_08542	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (903 aa)
	PTSG_08745	Uncharacterized protein. (393 aa)
	PTSG_12827	MHD domain-containing protein. (1662 aa)
	PTSG_12860	TKL protein kinase. (2208 aa)
	PTSG_10511	AP-1 complex subunit gamma. (801 aa)
	PTSG_10145	Uncharacterized protein. (1924 aa)
	PTSG_10212	Clathrin associated protein AP47; Belongs to the adaptor complexes medium subunit family. (408 aa)
	PTSG_10221	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (177 aa)
	PTSG_10222	Uncharacterized protein. (314 aa)
	PTSG_13008	I/LWEQ domain-containing protein. (802 aa)
	PTSG_10835	AP-3 complex subunit beta-1. (820 aa)
	PTSG_11427	Clat_adaptor_s domain-containing protein. (196 aa)

Your Current Organism:

Salpingoeca rosetta

NCBI taxonomy Id: 946362
Other names: Proterospongia sp. ATCC 50818, S. rosetta, Salpingoeca rosetta ATCC 50818, Salpingoeca rosetta ATCC50818, Salpingoeca rosetta Dayel et al. 2011, Salpingoeca sp. ATCC 50818, Salpingoeca sp. ATCC50818

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PTSG_00833	PTSG_01865	F2TXL7	F2TZ65	Uncharacterized protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.974
PTSG_00833	PTSG_01962	F2TXL7	F2TZG7	Uncharacterized protein.	NAK/GAK protein kinase.	0.798
PTSG_00833	PTSG_01983	F2TXL7	F2TZJ0	Uncharacterized protein.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.999
PTSG_00833	PTSG_02457	F2TXL7	F2U293	Uncharacterized protein.	50S ribosomal protein L27.	0.999
PTSG_00833	PTSG_02537	F2TXL7	F2U2H1	Uncharacterized protein.	Sortilin.	0.964
PTSG_00833	PTSG_02883	F2TXL7	F2U3L8	Uncharacterized protein.	ENTH domain-containing protein.	0.976
PTSG_00833	PTSG_02909	F2TXL7	F2U3P4	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.976
PTSG_00833	PTSG_03370	F2TXL7	F2U503	Uncharacterized protein.	Uncharacterized protein.	0.999
PTSG_00833	PTSG_03408	F2TXL7	F2U541	Uncharacterized protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
PTSG_00833	PTSG_03662	F2TXL7	F2U685	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.922
PTSG_00833	PTSG_04634	F2TXL7	F2U800	Uncharacterized protein.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.999
PTSG_00833	PTSG_04720	F2TXL7	F2U9I4	Uncharacterized protein.	NYN domain-containing protein.	0.975
PTSG_00833	PTSG_05451	F2TXL7	F2UB91	Uncharacterized protein.	Adaptin_N domain-containing protein.	0.952
PTSG_00833	PTSG_06130	F2TXL7	F2UC13	Uncharacterized protein.	Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.922
PTSG_00833	PTSG_06413	F2TXL7	F2UBY7	Uncharacterized protein.	Sortilin.	0.964
PTSG_00833	PTSG_06947	F2TXL7	F2UF95	Uncharacterized protein.	DUF1681 domain-containing protein.	0.985
PTSG_00833	PTSG_07711	F2TXL7	F2UHJ5	Uncharacterized protein.	ENTH domain-containing protein.	0.975
PTSG_00833	PTSG_08387	F2TXL7	F2UJJ5	Uncharacterized protein.	BTB_2 domain-containing protein.	0.999
PTSG_00833	PTSG_08421	F2TXL7	F2UJM8	Uncharacterized protein.	Coatomer.	0.999
PTSG_00833	PTSG_08542	F2TXL7	F2UJZ7	Uncharacterized protein.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.962

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