(24 nodes) Clathrin binding, and Sortilin, N-terminal network (Salpingoeca rosetta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTSG_00833	Uncharacterized protein. (524 aa)
	PTSG_01865	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (120 aa)
	PTSG_01962	NAK/GAK protein kinase. (307 aa)
	PTSG_01983	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family. (440 aa)
	PTSG_02431	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
	PTSG_02457	50S ribosomal protein L27. (134 aa)
	PTSG_02537	Sortilin. (1038 aa)
	PTSG_02883	ENTH domain-containing protein. (294 aa)
	PTSG_02909	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1667 aa)
	PTSG_03408	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	PTSG_03662	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (575 aa)
	PTSG_12113	AP4E_app_platf domain-containing protein. (1283 aa)
	PTSG_12118	ENTH domain-containing protein. (374 aa)
	PTSG_04634	AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (608 aa)
	PTSG_06413	Sortilin. (1168 aa)
	PTSG_06947	DUF1681 domain-containing protein. (272 aa)
	PTSG_07711	ENTH domain-containing protein. (628 aa)
	PTSG_08421	Coatomer. (871 aa)
	PTSG_08542	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (903 aa)
	PTSG_12827	MHD domain-containing protein. (1662 aa)
	PTSG_12860	TKL protein kinase. (2208 aa)
	PTSG_10511	AP-1 complex subunit gamma. (801 aa)
	PTSG_10212	Clathrin associated protein AP47; Belongs to the adaptor complexes medium subunit family. (408 aa)
	PTSG_10222	Uncharacterized protein. (314 aa)

Your Current Organism:

Salpingoeca rosetta

NCBI taxonomy Id: 946362
Other names: Proterospongia sp. ATCC 50818, S. rosetta, Salpingoeca rosetta ATCC 50818, Salpingoeca rosetta ATCC50818, Salpingoeca rosetta Dayel et al. 2011, Salpingoeca sp. ATCC 50818, Salpingoeca sp. ATCC50818

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PTSG_00833	PTSG_01865	F2TXL7	F2TZ65	Uncharacterized protein.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.974
PTSG_00833	PTSG_01962	F2TXL7	F2TZG7	Uncharacterized protein.	NAK/GAK protein kinase.	0.798
PTSG_00833	PTSG_01983	F2TXL7	F2TZJ0	Uncharacterized protein.	MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.	0.999
PTSG_00833	PTSG_02457	F2TXL7	F2U293	Uncharacterized protein.	50S ribosomal protein L27.	0.999
PTSG_00833	PTSG_02537	F2TXL7	F2U2H1	Uncharacterized protein.	Sortilin.	0.964
PTSG_00833	PTSG_02883	F2TXL7	F2U3L8	Uncharacterized protein.	ENTH domain-containing protein.	0.976
PTSG_00833	PTSG_02909	F2TXL7	F2U3P4	Uncharacterized protein.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.976
PTSG_00833	PTSG_03408	F2TXL7	F2U541	Uncharacterized protein.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.999
PTSG_00833	PTSG_03662	F2TXL7	F2U685	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.	0.922
PTSG_00833	PTSG_04634	F2TXL7	F2U800	Uncharacterized protein.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.999
PTSG_00833	PTSG_06413	F2TXL7	F2UBY7	Uncharacterized protein.	Sortilin.	0.964
PTSG_00833	PTSG_06947	F2TXL7	F2UF95	Uncharacterized protein.	DUF1681 domain-containing protein.	0.985
PTSG_00833	PTSG_07711	F2TXL7	F2UHJ5	Uncharacterized protein.	ENTH domain-containing protein.	0.975
PTSG_00833	PTSG_08421	F2TXL7	F2UJM8	Uncharacterized protein.	Coatomer.	0.999
PTSG_00833	PTSG_08542	F2TXL7	F2UJZ7	Uncharacterized protein.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.962
PTSG_00833	PTSG_10222	F2TXL7	F2UQN5	Uncharacterized protein.	Uncharacterized protein.	0.999
PTSG_00833	PTSG_10511	F2TXL7	F2UPV6	Uncharacterized protein.	AP-1 complex subunit gamma.	0.952
PTSG_00833	PTSG_12113	F2TXL7	F2U7H5	Uncharacterized protein.	AP4E_app_platf domain-containing protein.	0.952
PTSG_00833	PTSG_12118	F2TXL7	F2U7M2	Uncharacterized protein.	ENTH domain-containing protein.	0.976
PTSG_00833	PTSG_12827	F2TXL7	F2UM05	Uncharacterized protein.	MHD domain-containing protein.	0.987

page 1 of 25

Server load: low (12%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About