(25 nodes) Endosomal Sorting Complex Required For Transport (ESCRT), and BRO1 domain network (Salpingoeca rosetta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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protein homology

Your Input:
	PTSG_00583	BRO1 domain-containing protein. (896 aa)
	PTSG_01995	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (605 aa)
	PTSG_02006	Uncharacterized protein. (490 aa)
	PTSG_01088	Uncharacterized protein. (643 aa)
	PTSG_02438	Uncharacterized protein. (301 aa)
	PTSG_02615	Uncharacterized protein; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (245 aa)
	PTSG_02740	Uncharacterized protein. (208 aa)
	PTSG_11933	Uncharacterized protein. (57 aa)
	PTSG_12070	SpoU_methylase domain-containing protein. (717 aa)
	PTSG_12077	Uncharacterized protein. (780 aa)
	PTSG_04231	Uncharacterized protein; Belongs to the AAA ATPase family. (420 aa)
	PTSG_04426	USP domain-containing protein; Belongs to the peptidase C19 family. (1574 aa)
	PTSG_12230	Charged multivesicular body protein 5. (216 aa)
	PTSG_04736	Uncharacterized protein. (273 aa)
	PTSG_05883	Uncharacterized protein. (640 aa)
	PTSG_07044	Uncharacterized protein. (340 aa)
	PTSG_07194	Uncharacterized protein. (624 aa)
	PTSG_07213	Skd/vacuolar sorting protein; Belongs to the AAA ATPase family. (435 aa)
	PTSG_06904	PTPRS protein. (2281 aa)
	PTSG_06972	BRO1 domain-containing protein. (381 aa)
	PTSG_06666	Charged multivesicular body protein 2a. (194 aa)
	PTSG_08328	Uncharacterized protein. (216 aa)
	PTSG_08516	Vta1 domain-containing protein. (144 aa)
	PTSG_10749	GLUE N-terminal domain-containing protein. (440 aa)
	PTSG_10531	Uncharacterized protein. (202 aa)

Your Current Organism:

Salpingoeca rosetta

NCBI taxonomy Id: 946362
Other names: Proterospongia sp. ATCC 50818, S. rosetta, Salpingoeca rosetta ATCC 50818, Salpingoeca rosetta ATCC50818, Salpingoeca rosetta Dayel et al. 2011, Salpingoeca sp. ATCC 50818, Salpingoeca sp. ATCC50818

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PTSG_00583	PTSG_01995	F2TWW3	F2TZK2	BRO1 domain-containing protein.	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.	0.545
PTSG_00583	PTSG_02006	F2TWW3	F2TZL4	BRO1 domain-containing protein.	Uncharacterized protein.	0.878
PTSG_00583	PTSG_02438	F2TWW3	F2U275	BRO1 domain-containing protein.	Uncharacterized protein.	0.520
PTSG_00583	PTSG_02615	F2TWW3	F2U2T5	BRO1 domain-containing protein.	Uncharacterized protein; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.	0.450
PTSG_00583	PTSG_04231	F2TWW3	F2U6Z1	BRO1 domain-containing protein.	Uncharacterized protein; Belongs to the AAA ATPase family.	0.703
PTSG_00583	PTSG_04426	F2TWW3	F2U8I9	BRO1 domain-containing protein.	USP domain-containing protein; Belongs to the peptidase C19 family.	0.571
PTSG_00583	PTSG_04736	F2TWW3	F2U9J9	BRO1 domain-containing protein.	Uncharacterized protein.	0.652
PTSG_00583	PTSG_05883	F2TWW3	F2UD24	BRO1 domain-containing protein.	Uncharacterized protein.	0.594
PTSG_00583	PTSG_06666	F2TWW3	F2UFN1	BRO1 domain-containing protein.	Charged multivesicular body protein 2a.	0.625
PTSG_00583	PTSG_07213	F2TWW3	F2UEE0	BRO1 domain-containing protein.	Skd/vacuolar sorting protein; Belongs to the AAA ATPase family.	0.703
PTSG_00583	PTSG_08328	F2TWW3	F2UJD6	BRO1 domain-containing protein.	Uncharacterized protein.	0.952
PTSG_00583	PTSG_08516	F2TWW3	F2UJW8	BRO1 domain-containing protein.	Vta1 domain-containing protein.	0.570
PTSG_00583	PTSG_10531	F2TWW3	F2URM0	BRO1 domain-containing protein.	Uncharacterized protein.	0.843
PTSG_00583	PTSG_11933	F2TWW3	F2U3I6	BRO1 domain-containing protein.	Uncharacterized protein.	0.516
PTSG_00583	PTSG_12070	F2TWW3	F2U6G3	BRO1 domain-containing protein.	SpoU_methylase domain-containing protein.	0.641
PTSG_00583	PTSG_12077	F2TWW3	F2U6I0	BRO1 domain-containing protein.	Uncharacterized protein.	0.654
PTSG_00583	PTSG_12230	F2TWW3	F2U947	BRO1 domain-containing protein.	Charged multivesicular body protein 5.	0.589
PTSG_01088	PTSG_01995	F2U0S2	F2TZK2	Uncharacterized protein.	Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.	0.545
PTSG_01088	PTSG_02006	F2U0S2	F2TZL4	Uncharacterized protein.	Uncharacterized protein.	0.441
PTSG_01088	PTSG_05883	F2U0S2	F2UD24	Uncharacterized protein.	Uncharacterized protein.	0.411

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