(57 nodes) Mixed, incl. Homophilic cell adhesion via plasma membrane adhesion molecules, and Ras guanine nucleotide exchange factor domain superfamily network (Salpingoeca rosetta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTSG_00460	Uncharacterized protein. (621 aa)
	PTSG_11631	Uncharacterized protein. (1722 aa)
	PTSG_00851	Protein kintoun; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment. Belongs to the PIH1 family. Kintoun subfamily. (730 aa)
	PTSG_01036	Uncharacterized protein. (359 aa)
	PTSG_01662	Uncharacterized protein. (1216 aa)
	PTSG_01973	Protocadherin gamma B6. (1024 aa)
	PTSG_01986	NOTCH2 protein. (1763 aa)
	PTSG_01465	NOTCH2 protein. (2239 aa)
	PTSG_01501	Uncharacterized protein. (565 aa)
	PTSG_02229	Uncharacterized protein. (1069 aa)
	PTSG_02915	FAT3 protein. (7553 aa)
	PTSG_11959	Uncharacterized protein. (1378 aa)
	PTSG_03209	NOTCH2 protein. (2421 aa)
	PTSG_03266	Uncharacterized protein. (1988 aa)
	PTSG_12059	Ras-GEF domain-containing protein. (532 aa)
	PTSG_04118	Uncharacterized protein. (2117 aa)
	PTSG_12137	Uncharacterized protein. (799 aa)
	PTSG_04200	Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family. (231 aa)
	PTSG_04212	NAGPA domain-containing protein. (286 aa)
	PTSG_03898	SH2 domain-containing protein. (455 aa)
	PTSG_03957	SAYSvFN domain-containing protein. (172 aa)
	PTSG_04899	Uncharacterized protein. (786 aa)
	PTSG_04998	Uncharacterized protein. (804 aa)
	PTSG_04703	Uncharacterized protein. (2546 aa)
	PTSG_04795	Uncharacterized protein. (930 aa)
	PTSG_05657	Uncharacterized protein. (2254 aa)
	PTSG_06415	TK/ABL protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. (699 aa)
	PTSG_06318	AH domain-containing protein. (499 aa)
	PTSG_05849	Uncharacterized protein. (570 aa)
	PTSG_12381	Uncharacterized protein. (2415 aa)
	PTSG_07016	Uncharacterized protein. (8457 aa)
	PTSG_06730	Notch-1. (6376 aa)
	PTSG_06458	Cadherin. (3697 aa)
	PTSG_06480	Uncharacterized protein. (843 aa)
	PTSG_07781	Cation_ATPase_C domain-containing protein. (929 aa)
	PTSG_07946	Uncharacterized protein. (3300 aa)
	PTSG_07520	Uncharacterized protein. (947 aa)
	PTSG_12605	TK/ABL protein kinase. (2625 aa)
	PTSG_07273	Uncharacterized protein. (362 aa)
	PTSG_07361	Plasminogen. (4739 aa)
	PTSG_08442	PRCDH1 protein. (9674 aa)
	PTSG_08492	Ras-GEF domain-containing protein. (1698 aa)
	PTSG_08818	KIND domain-containing protein. (683 aa)
	PTSG_09639	Transmembrane protein 97. (173 aa)
	PTSG_08964	Uncharacterized protein. (996 aa)
	PTSG_09003	Response regulator receiver protein. (913 aa)
	PTSG_09152	Uncharacterized protein. (2183 aa)
	PTSG_09279	Uncharacterized protein. (952 aa)
	PTSG_12970	Uncharacterized protein. (10593 aa)
	PTSG_09814	Tyrosine-protein phosphatase domain-containing protein. (664 aa)
	PTSG_10435	Uncharacterized protein. (1222 aa)
	PTSG_10794	Uncharacterized protein. (1341 aa)
	PTSG_10712	SH2 domain-containing protein. (494 aa)
	PTSG_10171	Uncharacterized protein. (765 aa)
	PTSG_10294	Uncharacterized protein. (1488 aa)
	PTSG_10628	Uncharacterized protein. (873 aa)
	PTSG_10629	Ras-GEF domain-containing protein. (915 aa)

Your Current Organism:

Salpingoeca rosetta

NCBI taxonomy Id: 946362
Other names: Proterospongia sp. ATCC 50818, S. rosetta, Salpingoeca rosetta ATCC 50818, Salpingoeca rosetta ATCC50818, Salpingoeca rosetta Dayel et al. 2011, Salpingoeca sp. ATCC 50818, Salpingoeca sp. ATCC50818

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
PTSG_00460	PTSG_10171	F2TWJ4	F2UQI2	Uncharacterized protein.	Uncharacterized protein.	0.436
PTSG_00851	PTSG_06318	F2TXN5	F2UCK2	Protein kintoun; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment. Belongs to the PIH1 family. Kintoun subfamily.	AH domain-containing protein.	0.428
PTSG_01036	PTSG_03957	F2TY77	F2U7D2	Uncharacterized protein.	SAYSvFN domain-containing protein.	0.418
PTSG_01036	PTSG_10171	F2TY77	F2UQI2	Uncharacterized protein.	Uncharacterized protein.	0.436
PTSG_01465	PTSG_04795	F2U0F1	F2U9Q3	NOTCH2 protein.	Uncharacterized protein.	0.496
PTSG_01501	PTSG_04795	F2U0I9	F2U9Q3	Uncharacterized protein.	Uncharacterized protein.	0.496
PTSG_01662	PTSG_04795	F2TYK8	F2U9Q3	Uncharacterized protein.	Uncharacterized protein.	0.496
PTSG_01973	PTSG_04795	F2TZH8	F2U9Q3	Protocadherin gamma B6.	Uncharacterized protein.	0.496
PTSG_01973	PTSG_08964	F2TZH8	F2ULT7	Protocadherin gamma B6.	Uncharacterized protein.	0.456
PTSG_01986	PTSG_04795	F2TZJ3	F2U9Q3	NOTCH2 protein.	Uncharacterized protein.	0.496
PTSG_02229	PTSG_04795	F2U1K9	F2U9Q3	Uncharacterized protein.	Uncharacterized protein.	0.496
PTSG_02915	PTSG_04795	F2U3Q1	F2U9Q3	FAT3 protein.	Uncharacterized protein.	0.496
PTSG_03209	PTSG_04795	F2U4J1	F2U9Q3	NOTCH2 protein.	Uncharacterized protein.	0.496
PTSG_03957	PTSG_01036	F2U7D2	F2TY77	SAYSvFN domain-containing protein.	Uncharacterized protein.	0.418
PTSG_04118	PTSG_04795	F2U6M8	F2U9Q3	Uncharacterized protein.	Uncharacterized protein.	0.496
PTSG_04200	PTSG_06318	F2U6W0	F2UCK2	Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family.	AH domain-containing protein.	0.671
PTSG_04703	PTSG_06318	F2U9G7	F2UCK2	Uncharacterized protein.	AH domain-containing protein.	0.428
PTSG_04703	PTSG_10628	F2U9G7	F2URW8	Uncharacterized protein.	Uncharacterized protein.	0.698
PTSG_04795	PTSG_01465	F2U9Q3	F2U0F1	Uncharacterized protein.	NOTCH2 protein.	0.496
PTSG_04795	PTSG_01501	F2U9Q3	F2U0I9	Uncharacterized protein.	Uncharacterized protein.	0.496

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