135 items (Salpingoeca rosetta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTSG_00003	Uncharacterized protein. (1146 aa)
	PTSG_00021	Uncharacterized protein. (554 aa)
	PTSG_00069	Uncharacterized protein. (738 aa)
	PTSG_00124	RNA helicase. (522 aa)
	PTSG_00174	Uncharacterized protein; Belongs to the DEAD box helicase family. (321 aa)
	PTSG_00374	Uncharacterized protein. (852 aa)
	PTSG_00415	U3 small nucleolar ribonucleoprotein IMP3. (178 aa)
	PTSG_00419	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (262 aa)
	PTSG_00435	Zinc finger protein. (174 aa)
	PTSG_00624	ATP-dependent RNA helicase RhlE. (2578 aa)
	PTSG_00829	Uncharacterized protein. (255 aa)
	PTSG_00863	DEAD box polypeptide 17 isoform 2; Belongs to the DEAD box helicase family. (629 aa)
	PTSG_00898	U3 small nucleolar ribonucleoprotein IMP4. (283 aa)
	PTSG_00909	WD_REPEATS_REGION domain-containing protein. (898 aa)
	PTSG_00948	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. (934 aa)
	PTSG_00967	Protein MAK16 homolog; Belongs to the MAK16 family. (340 aa)
	PTSG_01067	RRM domain-containing protein. (590 aa)
	PTSG_01779	Brix domain-containing protein. (461 aa)
	PTSG_01785	WD_REPEATS_REGION domain-containing protein. (498 aa)
	PTSG_01917	Uncharacterized protein. (739 aa)
	PTSG_01945	RNA helicase. (845 aa)
	PTSG_01946	Uncharacterized protein. (628 aa)
	PTSG_02034	CP-type G domain-containing protein. (495 aa)
	PTSG_01250	Uncharacterized protein. (859 aa)
	PTSG_11725	ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (818 aa)
	PTSG_01466	Uncharacterized protein. (1170 aa)
	PTSG_01520	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family. (611 aa)
	PTSG_01177	rRNA 2'-O-methyltransferase fibrillarin. (323 aa)
	PTSG_01207	CBF domain-containing protein. (1180 aa)
	PTSG_02188	NUC153 domain-containing protein. (762 aa)
	PTSG_02477	Nle1 protein. (504 aa)
	PTSG_02517	DEAD/DEAH box helicase. (1034 aa)
	PTSG_02548	Uncharacterized protein. (690 aa)
	PTSG_03014	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (880 aa)
	PTSG_03052	C2f protein. (235 aa)
	PTSG_03092	Sas10 domain-containing protein. (541 aa)
	PTSG_03107	Uncharacterized protein. (484 aa)
	PTSG_03185	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (463 aa)
	PTSG_03192	WD_REPEATS_REGION domain-containing protein. (898 aa)
	PTSG_03196	RNA helicase. (857 aa)
	PTSG_03252	CK1/VRK protein kinase. (643 aa)
	PTSG_03265	Glutamate-rich WD repeat containing 1. (475 aa)
	PTSG_03292	Atypical/RIO/RIO1 protein kinase. (713 aa)
	PTSG_03331	GTP binding protein 4; Belongs to the sterol desaturase family. (635 aa)
	PTSG_03333	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (679 aa)
	PTSG_03361	Uncharacterized protein. (269 aa)
	PTSG_03386	BING4CT domain-containing protein. (528 aa)
	PTSG_03403	Uncharacterized protein. (1027 aa)
	PTSG_03457	Uncharacterized protein. (654 aa)
	PTSG_03467	Uncharacterized protein. (536 aa)
	PTSG_03712	Uncharacterized protein. (1339 aa)
	PTSG_03713	Methyltransferase WBSCR22. (282 aa)
	PTSG_04124	Uncharacterized protein. (632 aa)
	PTSG_04154	Zinc finger protein. (411 aa)
	PTSG_04185	NUC173 domain-containing protein. (1361 aa)
	PTSG_04211	zf-LYAR domain-containing protein. (368 aa)
	PTSG_03905	66S pre-ribosomal particle constituent. (146 aa)
	PTSG_12097	Uncharacterized protein. (476 aa)
	PTSG_03941	NLE domain-containing protein. (102 aa)
	PTSG_04011	DRIM domain-containing protein. (351 aa)
	PTSG_04540	Uncharacterized protein. (382 aa)
	PTSG_04552	Brix domain-containing protein. (326 aa)
	PTSG_04612	Uncharacterized protein. (1110 aa)
	PTSG_04654	Ribosomal protein L24E. (158 aa)
	PTSG_04684	Atypical/RIO/RIO2 protein kinase. (590 aa)
	PTSG_04319	WD_REPEATS_REGION domain-containing protein. (532 aa)
	PTSG_04398	Uncharacterized protein. (1275 aa)
	PTSG_04415	RNA-binding protein PNO1. (288 aa)
	PTSG_04968	WD_REPEATS_REGION domain-containing protein. (565 aa)
	PTSG_05013	Uncharacterized protein. (488 aa)
	PTSG_04729	BP28CT domain-containing protein. (2435 aa)
	PTSG_12213	Uncharacterized protein. (1010 aa)
	PTSG_04794	WD_REPEATS_REGION domain-containing protein. (643 aa)
	PTSG_05295	Brix domain-containing protein. (532 aa)
	PTSG_05094	Uncharacterized protein. (860 aa)
	PTSG_05728	Nucleolar protein 5A. (518 aa)
	PTSG_12358	DRIM domain-containing protein. (2776 aa)
	PTSG_05555	CK1/TTBK protein kinase. (1124 aa)
	PTSG_05591	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (590 aa)
	PTSG_05637	Peptidase_M24 domain-containing protein. (372 aa)
	PTSG_06405	Uncharacterized protein. (325 aa)
	PTSG_06419	PUM-HD domain-containing protein. (759 aa)
	PTSG_06324	Serine/Threonine protein kinase. (801 aa)
	PTSG_05801	Uncharacterized protein. (485 aa)
	PTSG_05845	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (455 aa)
	PTSG_05853	Uncharacterized protein. (481 aa)
	PTSG_05907	N-acetyltransferase domain-containing protein. (746 aa)
	PTSG_06025	RNA terminal phosphate cyclase domain 1. (368 aa)
	PTSG_07198	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (318 aa)
	PTSG_07209	DRIM domain-containing protein. (510 aa)
	PTSG_06701	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (718 aa)
	PTSG_06764	Ribosome production factor 1. (444 aa)
	PTSG_12503	WD_REPEATS_REGION domain-containing protein. (399 aa)
	PTSG_06978	Nsun6 protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (477 aa)
	PTSG_06596	CP-type G domain-containing protein. (760 aa)
	PTSG_06651	Uncharacterized protein. (837 aa)
	PTSG_06665	Proliferation-associated protein 2G4. (369 aa)
	PTSG_06452	Uncharacterized protein. (163 aa)
	PTSG_06512	PINc domain-containing protein. (206 aa)
	PTSG_07885	CK1/CK1/CK1-D protein kinase; Belongs to the protein kinase superfamily. (337 aa)
	PTSG_07591	Uncharacterized protein. (354 aa)
	PTSG_07597	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
	PTSG_08008	RRM domain-containing protein. (341 aa)
	PTSG_08012	60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
	EIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (237 aa)
	PTSG_08053	Uncharacterized protein. (1011 aa)
	PTSG_12680	Uncharacterized protein. (543 aa)
	PTSG_12681	Kri1_C domain-containing protein. (202 aa)
	PTSG_08255	Uncharacterized protein. (344 aa)
	PTSG_07428	Uncharacterized protein. (849 aa)
	PTSG_07289	GRIP domain-containing protein. (766 aa)
	PTSG_07360	Uncharacterized protein. (511 aa)
	PTSG_08869	ATP-dependent RNA helicase. (637 aa)
	PTSG_08905	Nucleolar protein 5. (516 aa)
	PTSG_09496	Uncharacterized protein. (642 aa)
	PTSG_08940	Uncharacterized protein. (478 aa)
	PTSG_09438	Uncharacterized protein. (521 aa)
	PTSG_12845	Uncharacterized protein. (984 aa)
	PTSG_09283	Uncharacterized protein; Belongs to the DEAD box helicase family. (448 aa)
	PTSG_09834	Uncharacterized protein. (457 aa)
	PTSG_09886	RNA helicase. (649 aa)
	PTSG_10085	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (1030 aa)
	PTSG_10088	WD_REPEATS_REGION domain-containing protein. (688 aa)
	PTSG_13095	Utp12 domain-containing protein. (705 aa)
	PTSG_10691	Uncharacterized protein. (1075 aa)
	PTSG_10152	Riok3 protein. (741 aa)
	PTSG_10186	MI domain-containing protein. (869 aa)
	PTSG_10269	Uncharacterized protein. (93 aa)
	PTSG_10831	Uncharacterized protein. (914 aa)
	PTSG_10839	WD_REPEATS_REGION domain-containing protein. (1090 aa)
	PTSG_10614	NUC153 domain-containing protein. (828 aa)
	PTSG_11198	WD repeats and SOF1 domain-containing protein. (511 aa)
	PTSG_11309	Bms1-type G domain-containing protein. (1064 aa)
	PTSG_11352	Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (180 aa)
	PTSG_11491	DEAD-box ATP-dependent RNA helicase 26; Belongs to the DEAD box helicase family. (648 aa)

Your Current Organism:

Salpingoeca rosetta

NCBI taxonomy Id: 946362
Other names: Proterospongia sp. ATCC 50818, S. rosetta, Salpingoeca rosetta ATCC 50818, Salpingoeca rosetta ATCC50818, Salpingoeca rosetta Dayel et al. 2011, Salpingoeca sp. ATCC 50818, Salpingoeca sp. ATCC50818

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF6	PTSG_00124	F2UHR4	F2TVL2	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	RNA helicase.	0.861
EIF6	PTSG_00374	F2UHR4	F2TWA8	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Uncharacterized protein.	0.744
EIF6	PTSG_00419	F2UHR4	F2TWF3	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.506
EIF6	PTSG_00435	F2UHR4	F2TWG9	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Zinc finger protein.	0.979
EIF6	PTSG_00948	F2UHR4	F2TXY7	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.	0.936
EIF6	PTSG_00967	F2UHR4	F2TY05	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Protein MAK16 homolog; Belongs to the MAK16 family.	0.828
EIF6	PTSG_01067	F2UHR4	F2TYA7	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	RRM domain-containing protein.	0.968
EIF6	PTSG_01177	F2UHR4	F2U112	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	rRNA 2'-O-methyltransferase fibrillarin.	0.726
EIF6	PTSG_01520	F2UHR4	F2U0K9	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.	0.978
EIF6	PTSG_01779	F2UHR4	F2TYY0	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Brix domain-containing protein.	0.924
EIF6	PTSG_02034	F2UHR4	F2TZP2	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	CP-type G domain-containing protein.	0.963
EIF6	PTSG_02477	F2UHR4	F2U2B2	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Nle1 protein.	0.862
EIF6	PTSG_02517	F2UHR4	F2U2F3	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	DEAD/DEAH box helicase.	0.511
EIF6	PTSG_02548	F2UHR4	F2U2I1	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Uncharacterized protein.	0.911
EIF6	PTSG_03014	F2UHR4	F2U406	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.827
EIF6	PTSG_03052	F2UHR4	F2U443	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	C2f protein.	0.489
EIF6	PTSG_03185	F2UHR4	F2U4G7	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.	0.986
EIF6	PTSG_03331	F2UHR4	F2U4V4	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	GTP binding protein 4; Belongs to the sterol desaturase family.	0.900
EIF6	PTSG_03333	F2UHR4	F2U4V6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.900
EIF6	PTSG_03361	F2UHR4	F2U4Y4	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Uncharacterized protein.	0.946

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