153 items (Salpingoeca rosetta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	PTSG_05511	40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family. (87 aa)
	PTSG_06405	Uncharacterized protein. (325 aa)
	PTSG_06324	Serine/Threonine protein kinase. (801 aa)
	PTSG_05801	Uncharacterized protein. (485 aa)
	PTSG_05810	KH_dom_type_1 domain-containing protein. (264 aa)
	PTSG_05816	Uncharacterized protein. (280 aa)
	PTSG_05821	Uncharacterized protein. (147 aa)
	PTSG_05853	Uncharacterized protein. (481 aa)
	PTSG_05854	CS domain-containing protein. (460 aa)
	PTSG_05907	N-acetyltransferase domain-containing protein. (746 aa)
	PTSG_06022	HIT-type domain-containing protein. (344 aa)
	PTSG_06069	PseudoU_synth_2 domain-containing protein. (224 aa)
	PTSG_06103	Uncharacterized protein. (732 aa)
	PTSG_07169	DEAD box polypeptide 47 isoform 1; Belongs to the DEAD box helicase family. (711 aa)
	PTSG_07198	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (318 aa)
	PTSG_07209	DRIM domain-containing protein. (510 aa)
	PTSG_07250	Uncharacterized protein; Belongs to the DEAD box helicase family. (751 aa)
	PTSG_06764	Ribosome production factor 1. (444 aa)
	PTSG_06814	RNase_PH domain-containing protein. (241 aa)
	PTSG_01466	Uncharacterized protein. (1170 aa)
	PTSG_06900	Squamous-cell carcinoma T-cell-recognized antigen. (725 aa)
	PTSG_06651	Uncharacterized protein. (837 aa)
	PTSG_11519	Uncharacterized protein. (126 aa)
	PTSG_11415	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (321 aa)
	PTSG_11309	Bms1-type G domain-containing protein. (1064 aa)
	PTSG_11198	WD repeats and SOF1 domain-containing protein. (511 aa)
	PTSG_11191	ATP-dependent RNA helicase DBP2; Belongs to the DEAD box helicase family. (553 aa)
	PTSG_11024	Uncharacterized protein. (255 aa)
	PTSG_10614	NUC153 domain-containing protein. (828 aa)
	PTSG_10839	WD_REPEATS_REGION domain-containing protein. (1090 aa)
	PTSG_10831	Uncharacterized protein. (914 aa)
	PTSG_10269	Uncharacterized protein. (93 aa)
	PTSG_10152	Riok3 protein. (741 aa)
	PTSG_13095	Utp12 domain-containing protein. (705 aa)
	PTSG_10085	Ribosome biogenesis protein BOP1 homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the WD repeat BOP1/ERB1 family. (1030 aa)
	PTSG_12966	Uncharacterized protein. (2005 aa)
	PTSG_09886	RNA helicase. (649 aa)
	PTSG_09834	Uncharacterized protein. (457 aa)
	PTSG_12845	Uncharacterized protein. (984 aa)
	PTSG_09438	Uncharacterized protein. (521 aa)
	PTSG_09333	Uncharacterized protein. (180 aa)
	PTSG_08940	Uncharacterized protein. (478 aa)
	PTSG_09667	Ribosomal_L30 domain-containing protein. (161 aa)
	PTSG_08905	Nucleolar protein 5. (516 aa)
	PTSG_08451	Peptidyl-prolyl cis-trans isomerase. (149 aa)
	PTSG_07367	HRDC domain-containing protein. (848 aa)
	PTSG_07506	Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences. (131 aa)
	PTSG_07492	G-patch domain-containing protein. (429 aa)
	PTSG_07428	Uncharacterized protein. (849 aa)
	PTSG_07411	Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (418 aa)
	PTSG_12681	Kri1_C domain-containing protein. (202 aa)
	PTSG_12680	Uncharacterized protein. (543 aa)
	PTSG_08109	Ribosomal protein L7A. (278 aa)
	PTSG_08089	Methyltransferase-like protein 5. (234 aa)
	PTSG_08053	Uncharacterized protein. (1011 aa)
	PTSG_08040	Uncharacterized protein. (312 aa)
	EIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (237 aa)
	PTSG_08008	RRM domain-containing protein. (341 aa)
	PTSG_12628	30S ribosomal protein S11. (244 aa)
	PTSG_07597	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
	PTSG_07573	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (207 aa)
	PTSG_06512	PINc domain-containing protein. (206 aa)
	PTSG_06452	Uncharacterized protein. (163 aa)
	PTSG_12503	WD_REPEATS_REGION domain-containing protein. (399 aa)
	PTSG_01520	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family. (611 aa)
	PTSG_13235	FDX-ACB domain-containing protein. (244 aa)
	PTSG_01177	rRNA 2'-O-methyltransferase fibrillarin. (323 aa)
	PTSG_11836	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (4118 aa)
	PTSG_02188	NUC153 domain-containing protein. (762 aa)
	PTSG_02202	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (510 aa)
	PTSG_02359	Rrp4-PA. (301 aa)
	PTSG_02517	DEAD/DEAH box helicase. (1034 aa)
	PTSG_02627	RNA exonuclease 4. (595 aa)
	PTSG_02697	Probable ribosome biogenesis protein PTSG_02697; Probable pre-rRNA processing protein involved in ribosome biogenesis. (333 aa)
	PTSG_02944	Uncharacterized protein. (233 aa)
	PTSG_03052	C2f protein. (235 aa)
	PTSG_03076	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (593 aa)
	PTSG_03092	Sas10 domain-containing protein. (541 aa)
	PTSG_03107	Uncharacterized protein. (484 aa)
	PTSG_03192	WD_REPEATS_REGION domain-containing protein. (898 aa)
	PTSG_03193	CLP1_P domain-containing protein. (666 aa)
	PTSG_03196	RNA helicase. (857 aa)
	PTSG_03292	Atypical/RIO/RIO1 protein kinase. (713 aa)
	PTSG_03361	Uncharacterized protein. (269 aa)
	PTSG_03386	BING4CT domain-containing protein. (528 aa)
	PTSG_03489	Centromere/microtubule-binding protein cbf5. (495 aa)
	PTSG_03607	60S ribosomal protein L35. (123 aa)
	PTSG_03695	Uncharacterized protein. (2185 aa)
	PTSG_03712	Uncharacterized protein. (1339 aa)
	PTSG_03713	Methyltransferase WBSCR22. (282 aa)
	PTSG_03738	H/ACA ribonucleoprotein complex subunit 3. (64 aa)
	PTSG_04124	Uncharacterized protein. (632 aa)
	PTSG_04185	NUC173 domain-containing protein. (1361 aa)
	PTSG_04209	PseudoU_synth_2 domain-containing protein. (293 aa)
	PTSG_04211	zf-LYAR domain-containing protein. (368 aa)
	PTSG_04262	Ipi1_N domain-containing protein. (1082 aa)
	PTSG_03905	66S pre-ribosomal particle constituent. (146 aa)
	PTSG_12097	Uncharacterized protein. (476 aa)
	PTSG_03941	NLE domain-containing protein. (102 aa)
	PTSG_12108	DUF2431 domain-containing protein. (492 aa)
	PTSG_04011	DRIM domain-containing protein. (351 aa)
	PTSG_04026	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (301 aa)
	PTSG_04540	Uncharacterized protein. (382 aa)
	PTSG_04552	Brix domain-containing protein. (326 aa)
	PTSG_04612	Uncharacterized protein. (1110 aa)
	PTSG_04684	Atypical/RIO/RIO2 protein kinase. (590 aa)
	PTSG_04319	WD_REPEATS_REGION domain-containing protein. (532 aa)
	PTSG_04333	Ribosomal protein L7. (243 aa)
	PTSG_04398	Uncharacterized protein. (1275 aa)
	PTSG_04876	Uncharacterized protein. (348 aa)
	PTSG_04968	WD_REPEATS_REGION domain-containing protein. (565 aa)
	PTSG_05064	LSM domain-containing protein. (77 aa)
	PTSG_04729	BP28CT domain-containing protein. (2435 aa)
	PTSG_04794	WD_REPEATS_REGION domain-containing protein. (643 aa)
	PTSG_05342	Uncharacterized protein. (539 aa)
	PTSG_05089	Ribosomal RNA-processing protein 8; Probable methyltransferase required to silence rDNA. Belongs to the methyltransferase superfamily. RRP8 family. (485 aa)
	PTSG_12358	DRIM domain-containing protein. (2776 aa)
	PTSG_05475	Uncharacterized protein. (497 aa)
	PTSG_00069	Uncharacterized protein. (738 aa)
	PTSG_00124	RNA helicase. (522 aa)
	PTSG_00174	Uncharacterized protein; Belongs to the DEAD box helicase family. (321 aa)
	PTSG_00374	Uncharacterized protein. (852 aa)
	PTSG_00415	U3 small nucleolar ribonucleoprotein IMP3. (178 aa)
	PTSG_00419	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (262 aa)
	PTSG_00527	Uncharacterized protein. (378 aa)
	PTSG_00547	Uncharacterized protein. (154 aa)
	PTSG_00620	ZNHIT2 protein. (282 aa)
	PTSG_00624	ATP-dependent RNA helicase RhlE. (2578 aa)
	PTSG_00771	Uncharacterized protein. (258 aa)
	PTSG_00800	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (216 aa)
	PTSG_00813	Uncharacterized protein. (219 aa)
	PTSG_00829	Uncharacterized protein. (255 aa)
	PTSG_00863	DEAD box polypeptide 17 isoform 2; Belongs to the DEAD box helicase family. (629 aa)
	PTSG_00897	Uncharacterized protein. (304 aa)
	PTSG_00898	U3 small nucleolar ribonucleoprotein IMP4. (283 aa)
	PTSG_00909	WD_REPEATS_REGION domain-containing protein. (898 aa)
	PTSG_00948	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits. (934 aa)
	PTSG_00967	Protein MAK16 homolog; Belongs to the MAK16 family. (340 aa)
	PTSG_01067	RRM domain-containing protein. (590 aa)
	PTSG_01640	eIF4AIII-PA; Belongs to the DEAD box helicase family. (366 aa)
	PTSG_01779	Brix domain-containing protein. (461 aa)
	PTSG_01785	WD_REPEATS_REGION domain-containing protein. (498 aa)
	PTSG_01913	Uncharacterized protein. (381 aa)
	PTSG_01917	Uncharacterized protein. (739 aa)
	PTSG_01926	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (168 aa)
	PTSG_01945	RNA helicase. (845 aa)
	PTSG_01946	Uncharacterized protein. (628 aa)
	PTSG_02031	rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (310 aa)
	PTSG_01250	Uncharacterized protein. (859 aa)
	PTSG_01357	HIT-type domain-containing protein. (182 aa)
	PTSG_01365	WD_REPEATS_REGION domain-containing protein. (567 aa)
	PTSG_01377	CTCHY-type domain-containing protein. (575 aa)
	PTSG_11725	ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (818 aa)

Your Current Organism:

Salpingoeca rosetta

NCBI taxonomy Id: 946362
Other names: Proterospongia sp. ATCC 50818, S. rosetta, Salpingoeca rosetta ATCC 50818, Salpingoeca rosetta ATCC50818, Salpingoeca rosetta Dayel et al. 2011, Salpingoeca sp. ATCC 50818, Salpingoeca sp. ATCC50818

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF6	PTSG_00124	F2UHR4	F2TVL2	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	RNA helicase.	0.861
EIF6	PTSG_00374	F2UHR4	F2TWA8	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Uncharacterized protein.	0.744
EIF6	PTSG_00419	F2UHR4	F2TWF3	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.	0.506
EIF6	PTSG_00547	F2UHR4	F2TWS8	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Uncharacterized protein.	0.471
EIF6	PTSG_00800	F2UHR4	F2TXI5	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.	0.985
EIF6	PTSG_00948	F2UHR4	F2TXY7	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Putative rRNA methyltransferase; Probable methyltransferase involved in the maturation of rRNA and in the biogenesis of ribosomal subunits.	0.936
EIF6	PTSG_00967	F2UHR4	F2TY05	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Protein MAK16 homolog; Belongs to the MAK16 family.	0.828
EIF6	PTSG_01067	F2UHR4	F2TYA7	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	RRM domain-containing protein.	0.968
EIF6	PTSG_01177	F2UHR4	F2U112	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	rRNA 2'-O-methyltransferase fibrillarin.	0.726
EIF6	PTSG_01365	F2UHR4	F2U048	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	WD_REPEATS_REGION domain-containing protein.	0.882
EIF6	PTSG_01520	F2UHR4	F2U0K9	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.	0.978
EIF6	PTSG_01640	F2UHR4	F2TYI7	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	eIF4AIII-PA; Belongs to the DEAD box helicase family.	0.603
EIF6	PTSG_01779	F2UHR4	F2TYY0	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Brix domain-containing protein.	0.924
EIF6	PTSG_01926	F2UHR4	F2TZC8	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.839
EIF6	PTSG_02202	F2UHR4	F2U1I3	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	0.555
EIF6	PTSG_02517	F2UHR4	F2U2F3	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	DEAD/DEAH box helicase.	0.511
EIF6	PTSG_03052	F2UHR4	F2U443	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	C2f protein.	0.489
EIF6	PTSG_03361	F2UHR4	F2U4Y4	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Uncharacterized protein.	0.946
EIF6	PTSG_03489	F2UHR4	F2U5R5	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	Centromere/microtubule-binding protein cbf5.	0.406
EIF6	PTSG_03607	F2UHR4	F2U630	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	60S ribosomal protein L35.	0.993

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