(39 nodes) Catalytic step 2 spliceosome network (Salpingoeca rosetta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PTSG_12784	Uncharacterized protein. (670 aa)
	PTSG_09527	Glutaredoxin-like protein; Belongs to the glutaredoxin family. (131 aa)
	PTSG_08050	Ppil2 protein. (526 aa)
	PTSG_09295	PSP domain-containing protein. (627 aa)
	PTSG_09200	Uncharacterized protein. (204 aa)
	PTSG_10832	Peptidyl-prolyl cis-trans isomerase. (601 aa)
	PTSG_11080	Dgcr14 protein. (649 aa)
	PTSG_11337	Uncharacterized protein. (208 aa)
	PTSG_07671	Pre-mRNA-splicing factor SYF1. (832 aa)
	PTSG_03123	Splicing factor 3b. (1242 aa)
	PTSG_12016	Peptidyl-prolyl cis-trans isomerase. (326 aa)
	PTSG_03391	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (165 aa)
	PTSG_12027	Pre-mRNA-processing factor 17. (554 aa)
	PTSG_04630	Small nuclear ribonucleoprotein G. (76 aa)
	PTSG_05432	Uncharacterized protein. (1211 aa)
	PTSG_05437	Aqr protein. (1659 aa)
	PTSG_05731	Uncharacterized protein. (231 aa)
	PTSG_12357	Sm domain-containing protein. (212 aa)
	PTSG_07630	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (161 aa)
	PTSG_06970	Sm domain-containing protein. (107 aa)
	PTSG_01085	Cyclophilin-16. (513 aa)
	LSM3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (91 aa)
	PTSG_02030	U5 snRNP-specific protein. (356 aa)
	PTSG_00931	PRP6 pre-mRNA processing factor 6. (926 aa)
	PTSG_00580	Uncharacterized protein. (283 aa)
	PTSG_00490	Mitogen-activated protein kinase organizer 1. (301 aa)
	PTSG_00373	Pinin_SDK_memA domain-containing protein. (300 aa)
	PTSG_00232	CMGC/DYRK/PRP4 protein kinase. (905 aa)
	PTSG_07246	Uncharacterized protein. (231 aa)
	PTSG_12691	Pre-mRNA-splicing factor RBM22. (336 aa)
	PTSG_08163	Splicing factor 3a. (233 aa)
	PTSG_07502	Crooked neck protein. (732 aa)
	PTSG_07503	SnRNP Sm protein F. (70 aa)
	PTSG_07115	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (295 aa)
	PTSG_00100	Splicing factor Prp8. (2525 aa)
	PTSG_05894	MI domain-containing protein. (981 aa)
	PTSG_02762	Eftud2 protein. (961 aa)
	PTSG_02543	Pre-mRNA-splicing factor prp46. (446 aa)
	PTSG_01137	Uncharacterized protein. (266 aa)

Your Current Organism:

Salpingoeca rosetta

NCBI taxonomy Id: 946362
Other names: Proterospongia sp. ATCC 50818, S. rosetta, Salpingoeca rosetta ATCC 50818, Salpingoeca rosetta ATCC50818, Salpingoeca rosetta Dayel et al. 2011, Salpingoeca sp. ATCC 50818, Salpingoeca sp. ATCC50818

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSM3	PTSG_00100	F2TZT7	F2TVI8	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Splicing factor Prp8.	0.992
LSM3	PTSG_00931	F2TZT7	F2TXX0	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	PRP6 pre-mRNA processing factor 6.	0.964
LSM3	PTSG_02030	F2TZT7	F2TZN8	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	U5 snRNP-specific protein.	0.562
LSM3	PTSG_02762	F2TZT7	F2U388	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Eftud2 protein.	0.992
LSM3	PTSG_03123	F2TZT7	F2U4A8	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Splicing factor 3b.	0.844
LSM3	PTSG_04630	F2TZT7	F2U7Z6	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein G.	0.980
LSM3	PTSG_05731	F2TZT7	F2UB24	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.621
LSM3	PTSG_06970	F2TZT7	F2UFC0	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Sm domain-containing protein.	0.999
LSM3	PTSG_07502	F2TZT7	F2UIX0	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Crooked neck protein.	0.961
LSM3	PTSG_07503	F2TZT7	F2UIX1	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	SnRNP Sm protein F.	0.978
LSM3	PTSG_07630	F2TZT7	F2UHB4	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.971
LSM3	PTSG_07671	F2TZT7	F2UHF7	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Pre-mRNA-splicing factor SYF1.	0.431
LSM3	PTSG_08163	F2TZT7	F2UI66	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Splicing factor 3a.	0.853
LSM3	PTSG_09295	F2TZT7	F2UM79	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	PSP domain-containing protein.	0.895
LSM3	PTSG_12357	F2TZT7	F2UB56	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Sm domain-containing protein.	0.991
LSM3	PTSG_12691	F2TZT7	F2UI61	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Pre-mRNA-splicing factor RBM22.	0.441
LSM3	PTSG_12784	F2TZT7	F2UKJ4	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.908
PTSG_00100	LSM3	F2TVI8	F2TZT7	Splicing factor Prp8.	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.992
PTSG_00100	PTSG_00232	F2TVI8	F2TVW5	Splicing factor Prp8.	CMGC/DYRK/PRP4 protein kinase.	0.845
PTSG_00100	PTSG_00373	F2TVI8	F2TWA7	Splicing factor Prp8.	Pinin_SDK_memA domain-containing protein.	0.457

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