STRINGSTRING
PTSG_08327 PTSG_08327 PTSG_11414 PTSG_11414 PTSG_11054 PTSG_11054 PTSG_10131 PTSG_10131 PTSG_10686 PTSG_10686 PTSG_12929 PTSG_12929 PTSG_09795 PTSG_09795 PTSG_09838 PTSG_09838 PTSG_09240 PTSG_09240 PTSG_09425 PTSG_09425 PTSG_09625 PTSG_09625 PTSG_09587 PTSG_09587 PTSG_09548 PTSG_09548 PTSG_08755 PTSG_08755 PTSG_07351 PTSG_07351 PTSG_08178 PTSG_08178 PTSG_12682 PTSG_12682 PTSG_07708 PTSG_07708 PTSG_12615 PTSG_12615 PTSG_12614 PTSG_12614 PTSG_07867 PTSG_07867 PTSG_06509 PTSG_06509 PTSG_06446 PTSG_06446 PTSG_06653 PTSG_06653 PTSG_06600 PTSG_06600 PTSG_06959 PTSG_06959 PTSG_06005 PTSG_06005 PTSG_05863 PTSG_05863 PTSG_06378 PTSG_06378 PTSG_06185 PTSG_06185 PTSG_05423 PTSG_05423 PTSG_05287 PTSG_05287 PTSG_04856 PTSG_04856 PTSG_04787 PTSG_04787 PTSG_04778 PTSG_04778 PTSG_04718 PTSG_04718 PTSG_04870 PTSG_04870 PTSG_04502 PTSG_04502 PTSG_04394 PTSG_04394 PTSG_12111 PTSG_12111 PTSG_03929 PTSG_03929 PTSG_04107 PTSG_04107 PTSG_03575 PTSG_03575 PTSG_03861 PTSG_03861 PTSG_03851 PTSG_03851 PTSG_03344 PTSG_03344 PTSG_02970 PTSG_02970 PTSG_02927 PTSG_02927 PTSG_02784 PTSG_02784 PTSG_02440 PTSG_02440 PTSG_02311 PTSG_02311 PTSG_01164 PTSG_01164 PTSG_01558 PTSG_01558 PTSG_01532 PTSG_01532 PTSG_11717 PTSG_11717 PTSG_11784 PTSG_11784 PTSG_01696 PTSG_01696 PTSG_01650 PTSG_01650 PTSG_01619 PTSG_01619 PTSG_01602 PTSG_01602 PTSG_01030 PTSG_01030 PTSG_00991 PTSG_00991 PTSG_00700 PTSG_00700 PTSG_11626 PTSG_11626 PTSG_11579 PTSG_11579 PTSG_00079 PTSG_00079 PTSG_00023 PTSG_00023 PTSG_00014 PTSG_00014
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTSG_08327Uncharacterized protein. (461 aa)
PTSG_11414DUF547 domain-containing protein. (207 aa)
PTSG_11054Uncharacterized protein; Belongs to the adenylate kinase family. (211 aa)
PTSG_10131Thioredoxin; Belongs to the thioredoxin family. (103 aa)
PTSG_10686Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (303 aa)
PTSG_12929Uncharacterized protein. (391 aa)
PTSG_09795Thioredoxin h isoform 1. (209 aa)
PTSG_09838UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (196 aa)
PTSG_09240PRK domain-containing protein. (265 aa)
PTSG_09425Deoxycytidylate deaminase. (185 aa)
PTSG_09625Thymidylate synthase. (293 aa)
PTSG_09587Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (235 aa)
PTSG_09548NHL repeat protein. (1505 aa)
PTSG_08755Dihydroorotate dehydrogenase. (424 aa)
PTSG_07351Nucleoside diphosphate kinase; Belongs to the NDK family. (656 aa)
PTSG_08178Uncharacterized protein. (555 aa)
PTSG_12682GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (382 aa)
PTSG_07708Xpo1 domain-containing protein. (935 aa)
PTSG_12615Uncharacterized protein. (165 aa)
PTSG_12614Cytosolic purine 5'-nucleotidase. (399 aa)
PTSG_07867Thymidine kinase. (218 aa)
PTSG_06509Uncharacterized protein; Belongs to the adenylate kinase family. (557 aa)
PTSG_06446Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (524 aa)
PTSG_06653Deoxycytidylate deaminase. (237 aa)
PTSG_06600Uridine kinase; Belongs to the uridine kinase family. (492 aa)
PTSG_06959Adenosine kinase b. (346 aa)
PTSG_06005Ectonucleoside triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family. (523 aa)
PTSG_05863AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (801 aa)
PTSG_063785'-nucleotidase domain containing 1. (667 aa)
PTSG_06185Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (438 aa)
PTSG_05423Uracil phosphoribosyltransferase. (217 aa)
PTSG_05287Thymidylate kinase. (213 aa)
PTSG_04856SAM domain-containing protein. (710 aa)
PTSG_04787GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (246 aa)
PTSG_04778CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (640 aa)
PTSG_04718Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (453 aa)
PTSG_04870Uncharacterized protein. (1699 aa)
PTSG_045025-aminoimidazole-4-carboxamide ribonucleotide transformylase. (601 aa)
PTSG_04394Uncharacterized protein; Belongs to the 5'-nucleotidase family. (647 aa)
PTSG_12111MutT/nudix family protein; Belongs to the Nudix hydrolase family. (372 aa)
PTSG_03929Deoxyuridine 5'-triphosphate nucleotidohydrolase. (187 aa)
PTSG_04107SAM domain and HD domain-containing protein 1. (580 aa)
PTSG_03575Glutaredoxin domain-containing protein. (119 aa)
PTSG_03861Adenylate kinase 2; Belongs to the adenylate kinase family. (222 aa)
PTSG_03851Ribonucleotide reductase M2 B. (408 aa)
PTSG_03344Orotidine 5'-monophosphate decarboxylase. (475 aa)
PTSG_02970Uncharacterized protein. (567 aa)
PTSG_02927Cytidylate kinase; Belongs to the adenylate kinase family. (228 aa)
PTSG_02784Nucleoside diphosphate kinase. (151 aa)
PTSG_02440Nudix-type domain-containing protein 6. (375 aa)
PTSG_02311CEP44 domain-containing protein. (867 aa)
PTSG_01164Glutaredoxin domain-containing protein. (137 aa)
PTSG_01558Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (779 aa)
PTSG_01532Nudix-type domain-containing protein 6. (310 aa)
PTSG_11717Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (416 aa)
PTSG_11784Uncharacterized protein. (652 aa)
PTSG_01696Uncharacterized protein. (226 aa)
PTSG_01650Guanylate kinase. (141 aa)
PTSG_01619Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (454 aa)
PTSG_01602Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (456 aa)
PTSG_01030GMP synthase. (662 aa)
PTSG_00991Pribosyltran domain-containing protein. (201 aa)
PTSG_00700Uncharacterized protein. (208 aa)
PTSG_11626Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (547 aa)
PTSG_11579Importin N-terminal domain-containing protein. (915 aa)
PTSG_00079Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (208 aa)
PTSG_00023Cytidine deaminase. (338 aa)
PTSG_00014Ecto-nucleosidase triphosphate diphosphohydrolase 5; Belongs to the GDA1/CD39 NTPase family. (513 aa)
Your Current Organism:
Salpingoeca rosetta
NCBI taxonomy Id: 946362
Other names: Proterospongia sp. ATCC 50818, S. rosetta, Salpingoeca rosetta ATCC 50818, Salpingoeca rosetta ATCC50818, Salpingoeca rosetta Dayel et al. 2011, Salpingoeca sp. ATCC 50818, Salpingoeca sp. ATCC50818
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