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KYNU KYNU PTSG_11822 PTSG_11822 PTSG_02619 PTSG_02619 PTSG_03349 PTSG_03349 PTSG_03836 PTSG_03836 PTSG_03628 PTSG_03628 PTSG_04446 PTSG_04446 PTSG_04447 PTSG_04447 PTSG_05426 PTSG_05426 PTSG_05774 PTSG_05774 PTSG_05665 PTSG_05665 PTSG_06292 PTSG_06292 PTSG_07214 PTSG_07214 PTSG_06450 PTSG_06450 PTSG_07579 PTSG_07579 PTSG_07452 PTSG_07452 PTSG_07353 PTSG_07353 PTSG_08382 PTSG_08382 PTSG_09009 PTSG_09009 PTSG_12968 PTSG_12968 PTSG_11030 PTSG_11030 PTSG_11163 PTSG_11163
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KYNUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (450 aa)
PTSG_11822Uncharacterized protein. (528 aa)
PTSG_02619Glutaryl-CoA dehydrogenase. (420 aa)
PTSG_03349Nitrile hydratase. (416 aa)
PTSG_03836Crotonase; Belongs to the enoyl-CoA hydratase/isomerase family. (287 aa)
PTSG_03628Uncharacterized protein. (246 aa)
PTSG_04446Aminotran_1_2 domain-containing protein. (297 aa)
PTSG_04447Aminotran_1_2 domain-containing protein. (313 aa)
PTSG_05426Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (560 aa)
PTSG_057743-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (281 aa)
PTSG_05665Kynurenine 3-monooxygenase. (365 aa)
PTSG_06292FAD_binding_3 domain-containing protein. (372 aa)
PTSG_07214Trifunctional enzyme subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (751 aa)
PTSG_06450Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (398 aa)
PTSG_07579Aldehyde dehydrogenase 7 family; Belongs to the aldehyde dehydrogenase family. (537 aa)
PTSG_07452Aminotran_1_2 domain-containing protein. (402 aa)
PTSG_07353Acetyl-Coenzyme A acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (415 aa)
PTSG_08382Dihydrolipoyl dehydrogenase. (506 aa)
PTSG_09009Aminotran_1_2 domain-containing protein. (308 aa)
PTSG_12968Dihydrolipoamide S-succinyltransferase. (442 aa)
PTSG_110302-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Belongs to the metallo-dependent hydrolases superfamily. (361 aa)
PTSG_11163Retinaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (885 aa)
Your Current Organism:
Salpingoeca rosetta
NCBI taxonomy Id: 946362
Other names: Proterospongia sp. ATCC 50818, S. rosetta, Salpingoeca rosetta ATCC 50818, Salpingoeca rosetta ATCC50818, Salpingoeca rosetta Dayel et al. 2011, Salpingoeca sp. ATCC 50818, Salpingoeca sp. ATCC50818
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