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BESB_024810 BESB_024810 BESB_019460 BESB_019460 BESB_021400 BESB_021400 BESB_032930 BESB_032930 BESB_026270 BESB_026270 BESB_018090 BESB_018090 BESB_026560 BESB_026560 BESB_019840 BESB_019840 BESB_075210 BESB_075210 BESB_017140 BESB_017140 BESB_066080 BESB_066080 BESB_068780 BESB_068780 BESB_082320 BESB_082320 BESB_014040 BESB_014040 BESB_014830 BESB_014830 BESB_052700 BESB_052700 BESB_079330 BESB_079330 BESB_070350 BESB_070350 BESB_056450 BESB_056450 BESB_074140 BESB_074140 BESB_068300 BESB_068300 BESB_059840 BESB_059840 BESB_040130 BESB_040130 BESB_040230 BESB_040230 BESB_050360 BESB_050360 BESB_034720 BESB_034720 BESB_052140 BESB_052140 BESB_011200 BESB_011200 BESB_044880 BESB_044880 BESB_056580 BESB_056580 BESB_006800 BESB_006800 BESB_043990 BESB_043990 BESB_049640 BESB_049640 BESB_034400 BESB_034400 BESB_004220 BESB_004220 BESB_039800 BESB_039800 BESB_001120 BESB_001120 BESB_006140 BESB_006140 BESB_009180 BESB_009180
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
BESB_0248102-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (414 aa)
BESB_019460Lactate dehydrogenase LDH2; Belongs to the LDH/MDH superfamily. (326 aa)
BESB_021400FAD Malate-dehydrogenase (MDH-FAD). (551 aa)
BESB_032930Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (462 aa)
BESB_026270Uncharacterized protein. (795 aa)
BESB_018090Pyruvate dehydrogenase complex subunit PDH-E3I. (651 aa)
BESB_026560Cyclic nucleotide-binding domain-containing protein. (3295 aa)
BESB_019840Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (332 aa)
BESB_075210Putative pyruvate dehydrogenase E1 component, beta subunit. (423 aa)
BESB_017140Carboxyvinyl-carboxyphosphonate phosphorylmutase. (308 aa)
BESB_066080Citrate synthase; Belongs to the citrate synthase family. (502 aa)
BESB_068780Putative dihydrolipoamide acyltransferase. (437 aa)
BESB_0823202-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (468 aa)
BESB_014040PH domain-containing protein. (1423 aa)
BESB_014830Putative 2-oxoglutarate dehydrogenase e1 component. (1119 aa)
BESB_052700Lipoyl-binding domain-containing protein. (738 aa)
BESB_079330Putative ATP-citrate lyase. (1320 aa)
BESB_070350Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (420 aa)
BESB_056450Dihydrolipoyl dehydrogenase. (528 aa)
BESB_074140Isocitrate dehydrogenase. (533 aa)
BESB_068300Ribose-phosphate diphosphokinase subfamily protein. (588 aa)
BESB_059840Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (978 aa)
BESB_040130Dihydrolipoyllysine-residue succinyltransferase component of oxoglutarate dehydrogenase. (471 aa)
BESB_040230Protein-serine/threonine kinase. (821 aa)
BESB_050360Fumarate hydratase. (615 aa)
BESB_034720Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (357 aa)
BESB_052140Citrate synthase; Belongs to the citrate synthase family. (555 aa)
BESB_011200Protein-serine/threonine kinase. (1129 aa)
BESB_044880Malate dehydrogenase MDH; Belongs to the LDH/MDH superfamily. (316 aa)
BESB_056580Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (968 aa)
BESB_006800Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (626 aa)
BESB_043990Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (511 aa)
BESB_049640Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (419 aa)
BESB_034400Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (674 aa)
BESB_004220Glutamate/leucine/phenylalanine/valine dehydrogenase family protein. (1116 aa)
BESB_039800NADPH-glutathione reductase. (622 aa)
BESB_001120Citrate synthase; Belongs to the citrate synthase family. (453 aa)
BESB_006140Glutathione reductase. (487 aa)
BESB_009180Lactate dehydrogenase LDH1; Belongs to the LDH/MDH superfamily. (329 aa)
Your Current Organism:
Besnoitia besnoiti
NCBI taxonomy Id: 94643
Other names: B. besnoiti
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