STRINGSTRING
BESB_045000 BESB_045000 BESB_045400 BESB_045400 BESB_022310 BESB_022310 BESB_022510 BESB_022510 BESB_014210 BESB_014210 BESB_085670 BESB_085670 BESB_079690 BESB_079690 BESB_070350 BESB_070350 BESB_064540 BESB_064540 BESB_031100 BESB_031100 BESB_030510 BESB_030510 FEN1 FEN1 BESB_025670 BESB_025670 BESB_072270 BESB_072270 BESB_023790 BESB_023790 BESB_012530 BESB_012530 BESB_011780 BESB_011780 BESB_068320 BESB_068320 BESB_077680 BESB_077680 BESB_062720 BESB_062720 BESB_009190 BESB_009190 BESB_036010 BESB_036010 BESB_049640 BESB_049640 BESB_034350 BESB_034350 BESB_044640 BESB_044640 BESB_050180 BESB_050180 BESB_045590 BESB_045590 BESB_007710 BESB_007710 BESB_005500 BESB_005500 BESB_005400 BESB_005400 BESB_009500 BESB_009500 BESB_008700 BESB_008700 BESB_060440 BESB_060440 BESB_059640 BESB_059640 BESB_068960 BESB_068960
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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BESB_045000Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (696 aa)
BESB_045400S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (402 aa)
BESB_022310Protein phosphatase; Belongs to the PP2C family. (522 aa)
BESB_022510Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (548 aa)
BESB_014210Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (224 aa)
BESB_085670Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis; Belongs to the adenylosuccinate synthetase family. (472 aa)
BESB_079690Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1362 aa)
BESB_070350Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (420 aa)
BESB_064540Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (230 aa)
BESB_031100Putative PP2C. (687 aa)
BESB_030510Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. (1137 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (539 aa)
BESB_025670Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (450 aa)
BESB_072270Protein phosphatase 2C domain-containing protein. (348 aa)
BESB_023790Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (4530 aa)
BESB_012530Protein phosphatase; Belongs to the PP2C family. (588 aa)
BESB_011780Pyruvate kinase; Belongs to the pyruvate kinase family. (935 aa)
BESB_068320Plasma membrane ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. (1051 aa)
BESB_077680Pyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
BESB_062720Inositol-1-monophosphatase. (297 aa)
BESB_009190Protein phosphatase 2C domain-containing protein. (578 aa)
BESB_036010PPM-type phosphatase domain-containing protein. (1010 aa)
BESB_049640Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (419 aa)
BESB_034350Protein phosphatase 2C domain-containing protein. (642 aa)
BESB_044640Putative PP2C. (538 aa)
BESB_050180PPM-type phosphatase domain-containing protein. (1116 aa)
BESB_045590Probable ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'Long' sub-subfamily. (1428 aa)
BESB_007710Magnesium transporter. (538 aa)
BESB_005500P-type phospholipid transporter. (2089 aa)
BESB_005400Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (2592 aa)
BESB_009500Uncharacterized protein. (3691 aa)
BESB_008700Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (663 aa)
BESB_060440Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (668 aa)
BESB_059640Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (1239 aa)
BESB_068960DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (631 aa)
Your Current Organism:
Besnoitia besnoiti
NCBI taxonomy Id: 94643
Other names: B. besnoiti
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