STRINGSTRING
OHU21028.1 OHU21028.1 OHU31341.1 OHU31341.1 korB korB korA korA kgd kgd aspA aspA sucD sucD sucC sucC gltA2 gltA2 OHU31159.1 OHU31159.1 ppc ppc OHU21446.1 OHU21446.1 OHU22744.1 OHU22744.1 OHU21609.1 OHU21609.1 OHU22772.1 OHU22772.1 OHU21655.1 OHU21655.1 OHU21751.1 OHU21751.1 OHU21809.1 OHU21809.1 OHU21817.1 OHU21817.1 aceA aceA OHU22878.1 OHU22878.1 sdhB_1 sdhB_1 OHU22187.1 OHU22187.1 OHU22188.1 OHU22188.1 OHU22189.1 OHU22189.1 OHU22359.1 OHU22359.1 OHU18965.1 OHU18965.1 mqo mqo OHU19424.1 OHU19424.1 glcB glcB mqo-2 mqo-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OHU21028.1MmgE/PrpD family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
OHU31341.12-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (583 aa)
korB2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
korA2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (653 aa)
kgdAlpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. (1232 aa)
aspAAspartate ammonia-lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (452 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa)
sucCsuccinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (387 aa)
gltA2Citrate (Si)-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (425 aa)
OHU31159.1Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (378 aa)
ppcHypothetical protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (929 aa)
OHU21446.12-methylcitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (373 aa)
OHU22744.12-methylcitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
OHU21609.1Succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
OHU22772.1NAD-dependent succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (471 aa)
OHU21655.1Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
OHU21751.1NAD-dependent succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (484 aa)
OHU21809.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (509 aa)
OHU21817.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
aceAIsocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
OHU22878.1Isocitrate dehydrogenase (NADP(+)); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (745 aa)
sdhB_1Succinate dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
OHU22187.1Succinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (592 aa)
OHU22188.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
OHU22189.1Succinate dehydrogenase, cytochrome b556 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa)
OHU22359.1NADP-dependent succinic semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
OHU18965.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (929 aa)
mqoMalate:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
OHU19424.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (516 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (731 aa)
mqo-2Malate:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
Your Current Organism:
Mycobacteroides franklinii
NCBI taxonomy Id: 948102
Other names: ATCC BAA-2149, DSM 45524, M. franklinii, Mycobacterium franklinii, Mycobacterium franklinii Nogueira et al. 2015, Mycobacterium sp. CV02, Mycobacteroides franklinii (Nogueira et al. 2015) Gupta et al. 2018, strain CV002
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