STRINGSTRING
metZ metZ ectB ectB OHU28939.1 OHU28939.1 OHU31503.1 OHU31503.1 OHU31269.1 OHU31269.1 OHU31490.1 OHU31490.1 OHU31207.1 OHU31207.1 serC serC OHU31147.1 OHU31147.1 OHU31108.1 OHU31108.1 lysA-2 lysA-2 OHU30911.1 OHU30911.1 OHU31435.1 OHU31435.1 glyA glyA OHU30847.1 OHU30847.1 OHU30800.1 OHU30800.1 lysA lysA OHU30716.1 OHU30716.1 OHU30688.1 OHU30688.1 cysM cysM OHU30504.1 OHU30504.1 OHU30503.1 OHU30503.1 OHU30486.1 OHU30486.1 OHU30437.1 OHU30437.1 OHU30401.1 OHU30401.1 OHU30311.1 OHU30311.1 hemL hemL OHU22851.1 OHU22851.1 OHU22140.1 OHU22140.1 OHU22141.1 OHU22141.1 OHU22179.1 OHU22179.1 OHU22883.1 OHU22883.1 OHU22443.1 OHU22443.1 OHU22488.1 OHU22488.1 OHU22521.1 OHU22521.1 OHU22554.1 OHU22554.1 OHU18844.1 OHU18844.1 OHU18950.1 OHU18950.1 ilvA ilvA bioA bioA OHU19003.1 OHU19003.1 hisC hisC OHU19050.1 OHU19050.1 OHU19400.1 OHU19400.1 argD argD OHU26812.1 OHU26812.1 OHU21679.1 OHU21679.1 OHU21614.1 OHU21614.1 OHU21404.1 OHU21404.1 OHU21023.1 OHU21023.1 OHU22802.1 OHU22802.1 pat pat OHU26826.1 OHU26826.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (410 aa)
ectBDiaminobutyrate--2-oxoglutarate transaminase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa)
OHU28939.1PPOX class F420-dependent enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
OHU31503.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
OHU31269.14-amino-4-deoxychorismate lyase; Catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
OHU31490.14-aminobutyrate--2-oxoglutarate transaminase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (434 aa)
OHU31207.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (371 aa)
OHU31147.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
OHU31108.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (486 aa)
lysA-2Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (448 aa)
OHU30911.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
OHU31435.1Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (487 aa)
OHU30847.1Pyridoxal-5'-phosphate-dependent protein subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
OHU30800.1Succinyldiaminopimelate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (470 aa)
OHU30716.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (355 aa)
OHU30688.1Glycogen phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (875 aa)
cysMCysteine synthase B; Catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
OHU30504.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (440 aa)
OHU30503.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
OHU30486.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (464 aa)
OHU30437.1Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (827 aa)
OHU30401.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
OHU30311.1YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. (236 aa)
hemLGlutamate-1-semialdehyde-2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
OHU22851.1Ornithine--oxo-acid transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (406 aa)
OHU22140.1Glutamate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the group II decarboxylase family. (472 aa)
OHU22141.1Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (397 aa)
OHU22179.1Bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
OHU22883.1L-lysine 6-transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (431 aa)
OHU22443.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
OHU22488.1Cysteine desulfurase NifS; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
OHU22521.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (461 aa)
OHU22554.1Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
OHU18844.1Glutamate-1-semialdehyde 2,1-aminomutase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (406 aa)
OHU18950.1Cysteine desulfurase; Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. (417 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (413 aa)
bioAAdenosylmethionine--8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (454 aa)
OHU19003.18-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
hisCHistidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (376 aa)
OHU19050.1Glutamate-1-semialdehyde 2,1-aminomutase; Catalyzes the formation of 5-aminovulinate from (S)-4-amino-5-oxopentanoate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (445 aa)
OHU19400.1Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
argDAspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (401 aa)
OHU26812.1MOSC domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
OHU21679.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
OHU21614.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (425 aa)
OHU21404.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
OHU21023.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (629 aa)
OHU22802.14-aminobutyrate--2-oxoglutarate transaminase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
patHistidinol-phosphate transaminase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (347 aa)
OHU26826.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
Your Current Organism:
Mycobacteroides franklinii
NCBI taxonomy Id: 948102
Other names: ATCC BAA-2149, DSM 45524, M. franklinii, Mycobacterium franklinii, Mycobacterium franklinii Nogueira et al. 2015, Mycobacterium sp. CV02, Mycobacteroides franklinii (Nogueira et al. 2015) Gupta et al. 2018, strain CV002
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