STRINGSTRING
OHU22077.1 OHU22077.1 OHU22008.1 OHU22008.1 gpsA gpsA OHU21973.1 OHU21973.1 OHU22249.1 OHU22249.1 purE purE purK purK OHU22222.1 OHU22222.1 upp upp OHU22183.1 OHU22183.1 guaA guaA OHU22250.1 OHU22250.1 OHU22257.1 OHU22257.1 tmk tmk OHU22393.1 OHU22393.1 nrdF2 nrdF2 OHU22502.1 OHU22502.1 gpsA-2 gpsA-2 ddl ddl coaD coaD dut dut dxs dxs OHU18769.1 OHU18769.1 OHU18811.1 OHU18811.1 OHU18818.1 OHU18818.1 OHU18819.1 OHU18819.1 apt apt OHU18835.1 OHU18835.1 atpE-2 atpE-2 OHU19366.1 OHU19366.1 mltG mltG pyrB pyrB pyrC pyrC OHU18880.1 OHU18880.1 carA carA carB carB pyrF pyrF OHU18888.1 OHU18888.1 OHU19001.1 OHU19001.1 OHU19051.1 OHU19051.1 OHU31722.1 OHU31722.1 OHU31659.1 OHU31659.1 OHU31706.1 OHU31706.1 murC murC murG murG OHU30316.1 OHU30316.1 murD murD mraY mraY murF murF murE murE OHU31331.1 OHU31331.1 OHU31333.1 OHU31333.1 OHU30338.1 OHU30338.1 OHU30506.1 OHU30506.1 ndk ndk OHU30633.1 OHU30633.1 murI murI cyaB_1 cyaB_1 murA murA atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH atpF atpF atpE atpE atpB atpB OHU30745.1 OHU30745.1 OHU30787.1 OHU30787.1 OHU30799.1 OHU30799.1 fbiC fbiC mtnP mtnP galE_1 galE_1 OHU21921.1 OHU21921.1 OHU21911.1 OHU21911.1 mshA mshA OHU21875.1 OHU21875.1 murB murB OHU21838.1 OHU21838.1 OHU21836.1 OHU21836.1 OHU21833.1 OHU21833.1 OHU21832.1 OHU21832.1 OHU21831.1 OHU21831.1 ackA ackA pta pta OHU21718.1 OHU21718.1 purA purA pyrE pyrE OHU21701.1 OHU21701.1 OHU21678.1 OHU21678.1 dcd dcd OHU21675.1 OHU21675.1 OHU21674.1 OHU21674.1 OHU21640.1 OHU21640.1 OHU21633.1 OHU21633.1 OHU21556.1 OHU21556.1 OHU22755.1 OHU22755.1 OHU21518.1 OHU21518.1 OHU21453.1 OHU21453.1 OHU21392.1 OHU21392.1 OHU21384.1 OHU21384.1 OHU21383.1 OHU21383.1 OHU22732.1 OHU22732.1 OHU21336.1 OHU21336.1 OHU21318.1 OHU21318.1 OHU22719.1 OHU22719.1 OHU21279.1 OHU21279.1 OHU21244.1 OHU21244.1 OHU21230.1 OHU21230.1 OHU21222.1 OHU21222.1 OHU22697.1 OHU22697.1 OHU21175.1 OHU21175.1 OHU21174.1 OHU21174.1 OHU21060.1 OHU21060.1 OHU21032.1 OHU21032.1 tgt tgt OHU20979.1 OHU20979.1 OHU20956.1 OHU20956.1 OHU22650.1 OHU22650.1 OHU20939.1 OHU20939.1 OHU20887.1 OHU20887.1 mshB mshB OHU22637.1 OHU22637.1 acsA acsA OHU20829.1 OHU20829.1 hpt hpt coaX coaX kanF kanF mshC mshC uppP uppP pyrD pyrD tcrX_2 tcrX_2 purD purD OHU31310.1 OHU31310.1 purC purC purS purS purQ purQ purL purL purF purF OHU31281.1 OHU31281.1 purM purM mshD mshD OHU31227.1 OHU31227.1 OHU31164.1 OHU31164.1 OHU31468.1 OHU31468.1 OHU31083.1 OHU31083.1 OHU31079.1 OHU31079.1 OHU31078.1 OHU31078.1 purN purN purH purH OHU30987.1 OHU30987.1 prs prs glmU glmU purT purT coaA coaA OHU30843.1 OHU30843.1 OHU30822.1 OHU30822.1 purU purU OHU30813.1 OHU30813.1 OHU19052.1 OHU19052.1 OHU19056.1 OHU19056.1 OHU19058.1 OHU19058.1 OHU19059.1 OHU19059.1 OHU19060.1 OHU19060.1 coaE coaE pyrG pyrG OHU19155.1 OHU19155.1 OHU19156.1 OHU19156.1 OHU19199.1 OHU19199.1 uppP-2 uppP-2 OHU18128.1 OHU18128.1 thyX thyX thyA thyA OHU18171.1 OHU18171.1 OHU18282.1 OHU18282.1 OHU18284.1 OHU18284.1 pyrH pyrH OHU18240.1 OHU18240.1 guaB guaB OHU22145.1 OHU22145.1 glmS glmS OHU22098.1 OHU22098.1 OHU22097.1 OHU22097.1 adk adk
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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OHU22077.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (185 aa)
OHU22008.1Diacylglycerol kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
gpsANAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (340 aa)
OHU21973.1Alpha-mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
OHU22249.1TIGR03089 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
purE5-(carboxyamino)imidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (158 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (393 aa)
OHU22222.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (213 aa)
OHU22183.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (429 aa)
guaAGlutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. (522 aa)
OHU22250.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (282 aa)
OHU22257.1Mannose-6-phosphate isomerase, class I; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (212 aa)
OHU22393.1NAD-dependent dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
nrdF2Class 1b ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (324 aa)
OHU22502.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (623 aa)
gpsA-2Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (326 aa)
ddlD-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (381 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (156 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (641 aa)
OHU18769.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
OHU18811.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (527 aa)
OHU18818.1Phosphatidylinositol mannoside acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
OHU18819.1Alpha-(1-2)-phosphatidylinositol mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (177 aa)
OHU18835.1GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (787 aa)
atpE-2ATP synthase F0 subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (82 aa)
OHU19366.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (429 aa)
pyrBAspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (317 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (433 aa)
OHU18880.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (376 aa)
carBCarbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarB family. (1112 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily. (282 aa)
OHU18888.1Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (419 aa)
OHU19001.1Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (726 aa)
OHU19051.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (436 aa)
OHU31722.1D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (273 aa)
OHU31659.1Ribose-phosphate pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
OHU31706.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0109 family. (80 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (490 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (373 aa)
OHU30316.1Cell division protein FtsW; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (524 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (485 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (359 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (505 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (519 aa)
OHU31331.1Cell division protein FtsI; Derived by automated computational analysis using gene prediction method: Protein Homology. (600 aa)
OHU31333.1DUF2029 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
OHU30338.1Alpha-(1-2)-phosphatidylinositol mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
OHU30506.1Nucleoside-diphosphate sugar epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (136 aa)
OHU30633.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (285 aa)
cyaB_1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (540 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (417 aa)
atpCF0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (121 aa)
atpDF0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (476 aa)
atpGF0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (310 aa)
atpAF0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (548 aa)
atpHF0F1 ATP synthase subunit B/delta; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction; Belongs to the ATPase delta chain family. (448 aa)
atpFF0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (177 aa)
atpEATP synthase F0 subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (83 aa)
atpBF0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (252 aa)
OHU30745.1Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
OHU30787.1NAD-dependent epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
OHU30799.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (655 aa)
fbiC7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase; catalyzes radical-mediated transfer of hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO); functions in F420 biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (857 aa)
mtnPMethylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (257 aa)
galE_1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
OHU21921.1Ribonucleotide-diphosphate reductase subunit beta; Catalyzes the rate-limiting step in dNTP synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
OHU21911.1Mycothiol conjugate amidase Mca; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
mshAD-inositol-3-phosphate glycosyltransferase; Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2- deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway. (443 aa)
OHU21875.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (361 aa)
OHU21838.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
OHU21836.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
OHU21833.1NAD-dependent dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
OHU21832.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
OHU21831.1Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (288 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (372 aa)
ptaPhosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (693 aa)
OHU21718.1Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate. Belongs to the PurK/PurT family. (489 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (431 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (190 aa)
OHU21701.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
OHU21678.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (446 aa)
dcddCTP deaminase; Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate. (189 aa)
OHU21675.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
OHU21674.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
OHU21640.1acetoacetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (627 aa)
OHU21633.1Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (237 aa)
OHU21556.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (74 aa)
OHU22755.1Adenylate/guanylate cyclase domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)
OHU21518.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
OHU21453.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
OHU21392.1Sterol 3-beta-glucosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
OHU21384.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
OHU21383.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
OHU22732.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
OHU21336.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
OHU21318.1Adenylate/guanylate cyclase domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
OHU22719.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
OHU21279.1acetoacetate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (657 aa)
OHU21244.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (793 aa)
OHU21230.1Pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
OHU21222.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family. (208 aa)
OHU22697.1Murein biosynthesis protein MurJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (1141 aa)
OHU21175.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
OHU21174.1Cell division protein FtsW; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (481 aa)
OHU21060.1Diacylglycerol acyltransferase/mycolyltransferase Ag85A; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
OHU21032.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (662 aa)
tgttRNA-guanine(34) transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form [...] (406 aa)
OHU20979.1Long-chain acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)
OHU20956.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)
OHU22650.1UDP-N-acetylmuramyl peptide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
OHU20939.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (161 aa)
OHU20887.1Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
mshBN-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase; Catalyzes the deacetylation of 1D-myo-inositol 2-acetamido-2- deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway. (278 aa)
OHU22637.1Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (648 aa)
OHU20829.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
hptHypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (193 aa)
coaXPantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (271 aa)
kanFGlycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
mshCcysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (416 aa)
uppPUndecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (276 aa)
pyrDDihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (353 aa)
tcrX_2DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
purDPhosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (419 aa)
OHU31310.1Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (472 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SAICAR synthetase family. (297 aa)
purSPhosphoribosylformylglycinamidine synthase subunit PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] (79 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (224 aa)
purLPhosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (761 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (504 aa)
OHU31281.1Epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
mshDMycothiol synthase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol. (296 aa)
OHU31227.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
OHU31164.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (628 aa)
OHU31468.13-beta hydroxysteroid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
OHU31083.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
OHU31079.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
OHU31078.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (223 aa)
purHBifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (517 aa)
OHU30987.1Dolichyl-phosphate-mannose--protein mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (328 aa)
glmUUDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (482 aa)
purTPhosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (402 aa)
coaAType I pantothenate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
OHU30843.1Glycosyl transferase family 39; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa)
OHU30822.1Alpha-(1-2)-phosphatidylinositol mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (299 aa)
OHU30813.1Monoacyl phosphatidylinositol tetramannoside-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (597 aa)
OHU19052.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (308 aa)
OHU19056.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
OHU19058.1dTDP-4-dehydrorhamnose 3,5-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
OHU19059.1NAD-dependent dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
OHU19060.1PIG-L family deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (395 aa)
pyrGCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (568 aa)
OHU19155.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
OHU19156.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
OHU19199.1Glycosyl transferase family 39; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
uppP-2Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (295 aa)
OHU18128.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (323 aa)
thyXFAD-dependent thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (250 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (266 aa)
OHU18171.1Riboflavin biosynthesis protein RibF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (320 aa)
OHU18282.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
OHU18284.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa)
OHU18240.1Aminodeoxychorismate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (515 aa)
OHU22145.1Ribosomal-protein-alanine N-acetyltransferase; Acetylates the N-terminal alanine of ribosomal protein S18. (155 aa)
glmSGlutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (621 aa)
OHU22098.1dTDP-glucose 4,6-dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (331 aa)
OHU22097.1dTDP-4-dehydrorhamnose 3,5-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (181 aa)
Your Current Organism:
Mycobacteroides franklinii
NCBI taxonomy Id: 948102
Other names: ATCC BAA-2149, DSM 45524, M. franklinii, Mycobacterium franklinii, Mycobacterium franklinii Nogueira et al. 2015, Mycobacterium sp. CV02, Mycobacteroides franklinii (Nogueira et al. 2015) Gupta et al. 2018, strain CV002
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