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OHU20741.1 OHU20741.1 OHU20730.1 OHU20730.1 OHU20724.1 OHU20724.1 OHU31491.1 OHU31491.1 OHU31224.1 OHU31224.1 OHU31217.1 OHU31217.1 OHU31204.1 OHU31204.1 OHU31159.1 OHU31159.1 gltA2 gltA2 OHU31127.1 OHU31127.1 OHU31101.1 OHU31101.1 OHU31467.1 OHU31467.1 OHU31017.1 OHU31017.1 OHU31453.1 OHU31453.1 OHU30916.1 OHU30916.1 glyA glyA purU purU OHU30749.1 OHU30749.1 OHU30742.1 OHU30742.1 mce mce OHU30692.1 OHU30692.1 OHU30664.1 OHU30664.1 OHU30658.1 OHU30658.1 OHU30577.1 OHU30577.1 OHU30444.1 OHU30444.1 accD6 accD6 OHU30402.1 OHU30402.1 OHU30355.1 OHU30355.1 gcvT gcvT glnA_2 glnA_2 OHU30384.1 OHU30384.1 OHU18259.1 OHU18259.1 OHU19337.1 OHU19337.1 gcvH gcvH gcvP gcvP glcB glcB OHU18981.1 OHU18981.1 OHU18980.1 OHU18980.1 OHU18965.1 OHU18965.1 OHU19375.1 OHU19375.1 OHU18736.1 OHU18736.1 OHU22573.1 OHU22573.1 OHU22905.1 OHU22905.1 OHU22235.1 OHU22235.1 OHU22219.1 OHU22219.1 OHU22056.1 OHU22056.1 OHU22021.1 OHU22021.1 hadB hadB OHU21848.1 OHU21848.1 OHU21847.1 OHU21847.1 aceA aceA OHU21817.1 OHU21817.1 OHU21781.1 OHU21781.1 OHU21647.1 OHU21647.1 OHU21617.1 OHU21617.1 OHU21613.1 OHU21613.1 OHU21590.1 OHU21590.1 OHU21516.1 OHU21516.1 OHU21446.1 OHU21446.1 OHU21321.1 OHU21321.1 OHU22718.1 OHU22718.1 OHU21272.1 OHU21272.1 OHU21155.1 OHU21155.1 OHU21142.1 OHU21142.1 OHU21054.1 OHU21054.1 OHU20936.1 OHU20936.1 acsA acsA OHU20754.1 OHU20754.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OHU20741.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (382 aa)
OHU20730.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (386 aa)
OHU20724.1Lipid-transfer protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
OHU31491.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (764 aa)
OHU31224.1Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
OHU31217.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
OHU31204.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
OHU31159.1Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (378 aa)
gltA2Citrate (Si)-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (425 aa)
OHU31127.1UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
OHU31101.1Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. (113 aa)
OHU31467.1Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (394 aa)
OHU31017.1acetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (673 aa)
OHU31453.1Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
OHU30916.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (487 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (299 aa)
OHU30749.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
OHU30742.1FAD-binding oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
mcemethylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
OHU30692.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
OHU30664.1Molybdopterin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (743 aa)
OHU30658.1Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
OHU30577.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (778 aa)
OHU30444.1Catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. (343 aa)
accD6propionyl-CoA carboxylase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
OHU30402.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
OHU30355.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycerate kinase type-1 family. (362 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (368 aa)
glnA_2Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
OHU30384.1Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (446 aa)
OHU18259.1Lipase; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
OHU19337.1Glutamine synthetase type III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (724 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (131 aa)
gcvPGlycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (945 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (731 aa)
OHU18981.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (759 aa)
OHU18980.1methylmalonyl-CoA mutase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (607 aa)
OHU18965.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (929 aa)
OHU19375.1Lipase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
OHU18736.1Mercuric reductase; Enables the enzymatic reduction of mercuric ions to elemental mercury; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
OHU22573.1Lipase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
OHU22905.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (445 aa)
OHU22235.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (536 aa)
OHU22219.1acetyl-/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)
OHU22056.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
OHU22021.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (726 aa)
hadB3-hydroxyacyl-ACP dehydratase; Functions as a heterodimer along with HadA or HadC in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
OHU21848.1Urea carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
OHU21847.1Urea carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
aceAIsocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
OHU21817.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
OHU21781.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
OHU21647.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (317 aa)
OHU21617.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (314 aa)
OHU21613.1Tartrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
OHU21590.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (443 aa)
OHU21516.1acetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (653 aa)
OHU21446.12-methylcitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (373 aa)
OHU21321.1Cupin; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
OHU22718.1(R)-hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
OHU21272.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
OHU21155.1Mycothione reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
OHU21142.1Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
OHU21054.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (517 aa)
OHU20936.1Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family. (487 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (648 aa)
OHU20754.1Formamidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
Your Current Organism:
Mycobacteroides franklinii
NCBI taxonomy Id: 948102
Other names: ATCC BAA-2149, DSM 45524, M. franklinii, Mycobacterium franklinii, Mycobacterium franklinii Nogueira et al. 2015, Mycobacterium sp. CV02, Mycobacteroides franklinii (Nogueira et al. 2015) Gupta et al. 2018, strain CV002
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