STRINGSTRING
OHU21155.1 OHU21155.1 accD6 accD6 OHU30666.1 OHU30666.1 OHU30692.1 OHU30692.1 mce mce OHU30916.1 OHU30916.1 OHU30919.1 OHU30919.1 OHU30921.1 OHU30921.1 echA8_1 echA8_1 OHU30934.1 OHU30934.1 OHU31447.1 OHU31447.1 OHU31017.1 OHU31017.1 OHU31019.1 OHU31019.1 sucD sucD sucC sucC OHU31127.1 OHU31127.1 OHU31477.1 OHU31477.1 OHU31147.1 OHU31147.1 OHU31203.1 OHU31203.1 OHU31204.1 OHU31204.1 OHU31217.1 OHU31217.1 OHU31218.1 OHU31218.1 OHU31220.1 OHU31220.1 OHU31490.1 OHU31490.1 OHU31296.1 OHU31296.1 OHU28957.1 OHU28957.1 OHU20724.1 OHU20724.1 OHU20730.1 OHU20730.1 OHU20735.1 OHU20735.1 OHU20741.1 OHU20741.1 acsA acsA OHU20960.1 OHU20960.1 OHU20979.1 OHU20979.1 OHU21027.1 OHU21027.1 OHU21028.1 OHU21028.1 OHU21054.1 OHU21054.1 OHU22678.1 OHU22678.1 OHU21145.1 OHU21145.1 OHU21310.1 OHU21310.1 OHU21401.1 OHU21401.1 OHU21447.1 OHU21447.1 OHU22744.1 OHU22744.1 caiD_5 caiD_5 OHU21488.1 OHU21488.1 OHU21516.1 OHU21516.1 OHU21590.1 OHU21590.1 OHU21599.1 OHU21599.1 OHU21614.1 OHU21614.1 pta pta ackA ackA OHU22802.1 OHU22802.1 OHU21770.1 OHU21770.1 OHU21781.1 OHU21781.1 OHU21785.1 OHU21785.1 OHU21817.1 OHU21817.1 OHU21930.1 OHU21930.1 OHU22029.1 OHU22029.1 OHU22030.1 OHU22030.1 OHU22056.1 OHU22056.1 OHU22883.1 OHU22883.1 OHU22219.1 OHU22219.1 OHU22235.1 OHU22235.1 OHU22249.1 OHU22249.1 OHU22268.1 OHU22268.1 OHU22280.1 OHU22280.1 OHU22447.1 OHU22447.1 OHU22496.1 OHU22496.1 OHU18736.1 OHU18736.1 OHU18877.1 OHU18877.1 OHU18958.1 OHU18958.1 OHU18980.1 OHU18980.1 OHU18981.1 OHU18981.1 OHU19235.1 OHU19235.1 paaF_4 paaF_4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OHU21155.1Mycothione reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
accD6propionyl-CoA carboxylase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
OHU30666.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
OHU30692.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
mcemethylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
OHU30916.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (405 aa)
OHU30919.1Methylmalonate-semialdehyde dehydrogenase (acylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
OHU30921.13-hydroxyisobutyryl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
echA8_1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
OHU30934.1Peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
OHU31447.1Peroxidase; Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the tetrapyrrol ring intact. Belongs to the DyP-type peroxidase family. (408 aa)
OHU31017.1acetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (673 aa)
OHU31019.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa)
sucCsuccinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (387 aa)
OHU31127.1UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
OHU31477.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (243 aa)
OHU31147.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (439 aa)
OHU31203.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (719 aa)
OHU31204.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
OHU31217.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
OHU31218.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
OHU31220.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa)
OHU31490.14-aminobutyrate--2-oxoglutarate transaminase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (434 aa)
OHU31296.1Peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
OHU28957.1Peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
OHU20724.1Lipid-transfer protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
OHU20730.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (386 aa)
OHU20735.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
OHU20741.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (382 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (648 aa)
OHU20960.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
OHU20979.1Long-chain acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)
OHU21027.1Carboxyvinyl-carboxyphosphonate phosphorylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
OHU21028.1MmgE/PrpD family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
OHU21054.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (517 aa)
OHU22678.1Carboxylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
OHU21145.1Cyclohexanone monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (537 aa)
OHU21310.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (249 aa)
OHU21401.1Biotin carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)
OHU21447.1Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (304 aa)
OHU22744.12-methylcitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
caiD_5enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (252 aa)
OHU21488.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
OHU21516.1acetyl/propionyl-CoA carboxylase subuit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (653 aa)
OHU21590.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (443 aa)
OHU21599.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (265 aa)
OHU21614.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (425 aa)
ptaPhosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (693 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (372 aa)
OHU22802.14-aminobutyrate--2-oxoglutarate transaminase; Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (449 aa)
OHU21770.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
OHU21781.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
OHU21785.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
OHU21817.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
OHU21930.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
OHU22029.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
OHU22030.1enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
OHU22056.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
OHU22883.1L-lysine 6-transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (431 aa)
OHU22219.1acetyl-/propionyl-CoA carboxylase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)
OHU22235.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (536 aa)
OHU22249.1TIGR03089 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
OHU22268.1acyl-CoA oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (649 aa)
OHU22280.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (72 aa)
OHU22447.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
OHU22496.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
OHU18736.1Mercuric reductase; Enables the enzymatic reduction of mercuric ions to elemental mercury; Derived by automated computational analysis using gene prediction method: Protein Homology. (458 aa)
OHU18877.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
OHU18958.1enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (269 aa)
OHU18980.1methylmalonyl-CoA mutase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (607 aa)
OHU18981.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (759 aa)
OHU19235.1Carboxyvinyl-carboxyphosphonate phosphorylmutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
paaF_4enoyl-CoA hydratase; Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
Your Current Organism:
Mycobacteroides franklinii
NCBI taxonomy Id: 948102
Other names: ATCC BAA-2149, DSM 45524, M. franklinii, Mycobacterium franklinii, Mycobacterium franklinii Nogueira et al. 2015, Mycobacterium sp. CV02, Mycobacteroides franklinii (Nogueira et al. 2015) Gupta et al. 2018, strain CV002
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