STRINGSTRING
OHU22338.1 OHU22338.1 OHU31659.1 OHU31659.1 OHU31334.1 OHU31334.1 trpD trpD OHU30351.1 OHU30351.1 OHU30361.1 OHU30361.1 glnA_2 glnA_2 OHU31342.1 OHU31342.1 OHU30384.1 OHU30384.1 OHU30401.1 OHU30401.1 OHU30504.1 OHU30504.1 proA proA proB proB OHU30593.1 OHU30593.1 OHU30661.1 OHU30661.1 thrB thrB OHU30716.1 OHU30716.1 OHU30717.1 OHU30717.1 lysA lysA OHU30794.1 OHU30794.1 dapD dapD OHU30800.1 OHU30800.1 glyA glyA OHU31435.1 OHU31435.1 OHU30911.1 OHU30911.1 cbs cbs eno eno lysA-2 lysA-2 prs prs rsmA rsmA OHU30984.1 OHU30984.1 OHU31036.1 OHU31036.1 OHU31042.1 OHU31042.1 OHU31099.1 OHU31099.1 OHU31143.1 OHU31143.1 OHU31145.1 OHU31145.1 gltA2 gltA2 OHU31159.1 OHU31159.1 serC serC OHU31207.1 OHU31207.1 OHU31273.1 OHU31273.1 OHU31503.1 OHU31503.1 ectB ectB OHU28977.1 OHU28977.1 OHU26767.1 OHU26767.1 OHU26773.1 OHU26773.1 OHU26888.1 OHU26888.1 hisE hisE hisG hisG OHU26897.1 OHU26897.1 OHU26826.1 OHU26826.1 OHU26856.1 OHU26856.1 OHU26875.1 OHU26875.1 OHU22634.1 OHU22634.1 OHU20877.1 OHU20877.1 OHU20886.1 OHU20886.1 asd asd OHU20942.1 OHU20942.1 leuA leuA eno-2 eno-2 OHU20974.1 OHU20974.1 OHU22661.1 OHU22661.1 pat pat OHU21025.1 OHU21025.1 OHU21026.1 OHU21026.1 OHU22663.1 OHU22663.1 OHU22666.1 OHU22666.1 pheA pheA OHU21127.1 OHU21127.1 gltD gltD OHU21132.1 OHU21132.1 OHU22710.1 OHU22710.1 OHU21351.1 OHU21351.1 metE metE OHU21446.1 OHU21446.1 ilvD ilvD OHU21574.1 OHU21574.1 OHU21633.1 OHU21633.1 OHU21679.1 OHU21679.1 OHU22794.1 OHU22794.1 OHU21730.1 OHU21730.1 OHU22803.1 OHU22803.1 gpmA gpmA proC proC OHU22092.1 OHU22092.1 metXA metXA OHU22878.1 OHU22878.1 OHU22233.1 OHU22233.1 aroA aroA OHU22905.1 OHU22905.1 OHU22291.1 OHU22291.1 OHU22299.1 OHU22299.1 OHU22360.1 OHU22360.1 OHU22926.1 OHU22926.1 OHU22494.1 OHU22494.1 pfkA pfkA OHU22522.1 OHU22522.1 OHU22524.1 OHU22524.1 OHU22525.1 OHU22525.1 ilvC ilvC OHU22539.1 OHU22539.1 leuB leuB leuC leuC leuD leuD OHU22554.1 OHU22554.1 OHU22576.1 OHU22576.1 OHU19360.1 OHU19360.1 OHU18843.1 OHU18843.1 OHU18865.1 OHU18865.1 aroC aroC aroK aroK aroB aroB aroQ aroQ metK metK OHU18897.1 OHU18897.1 OHU18925.1 OHU18925.1 pgk pgk tpiA tpiA tal tal OHU18937.1 OHU18937.1 OHU18965.1 OHU18965.1 OHU18988.1 OHU18988.1 ilvA ilvA hisD hisD hisC hisC hisB hisB hisH hisH priA-2 priA-2 hisF hisF hisI hisI trpE trpE trpC trpC trpB trpB trpA trpA OHU19041.1 OHU19041.1 OHU19091.1 OHU19091.1 argC argC argJ argJ argB argB argD argD OHU19115.1 OHU19115.1 argG argG argH argH ilvD-2 ilvD-2 OHU19236.1 OHU19236.1 OHU19237.1 OHU19237.1 OHU19246.1 OHU19246.1 OHU19271.1 OHU19271.1 OHU19337.1 OHU19337.1 dapF dapF OHU18141.1 OHU18141.1 OHU18262.1 OHU18262.1 OHU18264.1 OHU18264.1 dapA dapA dapB dapB OHU18192.1 OHU18192.1 OHU18285.1 OHU18285.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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OHU22338.1Histidinol-phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
OHU31659.1Ribose-phosphate pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
OHU31334.13-deoxy-7-phosphoheptulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (462 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (355 aa)
OHU30351.1Asparagine synthase (glutamine-hydrolyzing); Derived by automated computational analysis using gene prediction method: Protein Homology. (642 aa)
OHU30361.1Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
glnA_2Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
OHU31342.1Benzoylformate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (537 aa)
OHU30384.1Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (446 aa)
OHU30401.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
OHU30504.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (440 aa)
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (438 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (368 aa)
OHU30593.1Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
OHU30661.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (339 aa)
OHU30716.1Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (355 aa)
OHU30717.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (470 aa)
OHU30794.1Succinyl-diaminopimelate desuccinylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (315 aa)
OHU30800.1Succinyldiaminopimelate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (487 aa)
OHU31435.1Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
OHU30911.1Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
cbsCystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
lysA-2Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (448 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (328 aa)
rsmA16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (298 aa)
OHU30984.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
OHU31036.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)
OHU31042.1Dihydrodipicolinate synthase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (295 aa)
OHU31099.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
OHU31143.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
OHU31145.1Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
gltA2Citrate (Si)-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (425 aa)
OHU31159.1Citrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (378 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (371 aa)
OHU31207.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
OHU31273.1Dihydrodipicolinate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa)
OHU31503.1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
ectBDiaminobutyrate--2-oxoglutarate transaminase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa)
OHU28977.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
OHU26767.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
OHU26773.1Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
OHU26888.1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1251 aa)
hisEphosphoribosyl-ATP diphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (293 aa)
OHU26897.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (566 aa)
OHU26826.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
OHU26856.1Membrane protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
OHU26875.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (536 aa)
OHU22634.1Inhibition of morphological differentiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
OHU20877.1Lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
OHU20886.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (345 aa)
OHU20942.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (421 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (608 aa)
eno-2Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (424 aa)
OHU20974.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (393 aa)
OHU22661.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
patHistidinol-phosphate transaminase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (347 aa)
OHU21025.13-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LeuD family. (184 aa)
OHU21026.13-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
OHU22663.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
OHU22666.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
pheAPrephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
OHU21127.1PHP domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
OHU21132.1Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1534 aa)
OHU22710.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
OHU21351.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
metE5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (756 aa)
OHU21446.12-methylcitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (373 aa)
ilvDDihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (567 aa)
OHU21574.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
OHU21633.1Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (237 aa)
OHU21679.1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
OHU22794.1Class II fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (347 aa)
OHU21730.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
OHU22803.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (256 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (299 aa)
OHU22092.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (424 aa)
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (365 aa)
OHU22878.1Isocitrate dehydrogenase (NADP(+)); Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (745 aa)
OHU22233.1Septum formation inhibitor Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (565 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (432 aa)
OHU22905.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (445 aa)
OHU22291.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
OHU22299.1TIGR02569 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
OHU22360.1Acetolactate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (547 aa)
OHU22926.1Phosphoserine phosphatase SerB; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
OHU22494.1Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (343 aa)
OHU22522.1ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
OHU22524.1Acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (617 aa)
OHU22525.1Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa)
OHU22539.1Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (529 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (337 aa)
leuC3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (480 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (199 aa)
OHU22554.1Cystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
OHU22576.1Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1127 aa)
OHU19360.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
OHU18843.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
OHU18865.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the shikimate dehydrogenase family. (271 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (401 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (216 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (369 aa)
aroQType II 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (144 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (400 aa)
OHU18897.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (221 aa)
OHU18925.1Type I glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (340 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (412 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (375 aa)
OHU18937.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. (705 aa)
OHU18965.1Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (929 aa)
OHU18988.1Methyltransferase type 11; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (413 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (449 aa)
hisCHistidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (376 aa)
hisBImidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (216 aa)
priA-2Phosphoribosyl isomerase A; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family. (243 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (116 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (511 aa)
trpCIndole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (272 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (419 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (262 aa)
OHU19041.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (444 aa)
OHU19091.1Peptidase M20; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (347 aa)
argJBifunctional ornithine acetyltransferase/N-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (404 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (290 aa)
argDAspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (401 aa)
OHU19115.1Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (312 aa)
argGArgininosuccinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (406 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
ilvD-2Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (600 aa)
OHU19236.13-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
OHU19237.13-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (214 aa)
OHU19246.1Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (1759 aa)
OHU19271.1Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
OHU19337.1Glutamine synthetase type III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (724 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (295 aa)
OHU18141.14-amino-4-deoxychorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
OHU18262.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
OHU18264.1N-acetylglutamate synthase; Catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family. (162 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (281 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (227 aa)
OHU18192.1Hemin transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the globin family. (396 aa)
OHU18285.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
Your Current Organism:
Mycobacteroides franklinii
NCBI taxonomy Id: 948102
Other names: ATCC BAA-2149, DSM 45524, M. franklinii, Mycobacterium franklinii, Mycobacterium franklinii Nogueira et al. 2015, Mycobacterium sp. CV02, Mycobacteroides franklinii (Nogueira et al. 2015) Gupta et al. 2018, strain CV002
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