(48 nodes) Mixed, incl. Clathrin coat, and Regulation of clathrin-dependent endocytosis network (Tinamus guttatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N309_03475	ADP-ribosylation factor-like 5B; Belongs to the small GTPase superfamily. Arf family. (166 aa)
	N309_07024	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa)
	N309_07808	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	N309_10142	Epidermal growth factor receptor substrate 15-like 1. (870 aa)
	N309_02298	AP-5 complex subunit mu-1. (468 aa)
	N309_13015	AP-3 complex subunit delta-1. (787 aa)
	N309_12260	FCH domain only protein 2. (631 aa)
	N309_08525	AP-2 complex subunit alpha-2. (918 aa)
	N309_05604	AP-3 complex subunit beta-2. (836 aa)
	N309_09946	Huntingtin-interacting protein 1. (867 aa)
	N309_03102	Intersectin-1. (1704 aa)
	N309_08734	Synaptotagmin-9. (442 aa)
	N309_02984	Adaptin ear-binding coat-associated protein 1. (240 aa)
	N309_06428	Intersectin-2. (1055 aa)
	N309_10665	Putative tyrosine-protein phosphatase auxilin. (574 aa)
	N309_07215	RalA-binding protein 1. (650 aa)
	N309_11967	Synaptotagmin-11. (417 aa)
	N309_01119	Clathrin coat assembly protein AP180. (443 aa)
	N309_03733	AP-3 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family. (396 aa)
	N309_05385	Huntingtin. (3058 aa)
	N309_12078	Phosphatidylinositol-binding clathrin assembly protein. (562 aa)
	N309_03020	Epsin-2. (529 aa)
	N309_08376	Synaptotagmin-2. (404 aa)
	N309_11697	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (165 aa)
	N309_08521	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (140 aa)
	N309_01816	AP-4 complex subunit beta-1. (269 aa)
	N309_00261	AP-1 complex subunit gamma. (818 aa)
	N309_04432	BMP-2-inducible protein kinase. (418 aa)
	N309_02065	Epsin-3. (463 aa)
	N309_04009	Proline-serine-threonine phosphatase-interacting protein 2. (310 aa)
	N309_15586	AP-2 complex subunit sigma. (64 aa)
	N309_10739	Clathrin heavy chain linker domain-containing protein 1. (566 aa)
	N309_12657	Synergin gamma. (1289 aa)
	N309_00646	RalBP1-associated Eps domain-containing protein 2. (340 aa)
	N309_14523	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (170 aa)
	N309_09918	Non-lysosomal glucosylceramidase. (787 aa)
	N309_04720	Huntingtin-interacting protein 1-related protein. (830 aa)
	N309_07702	Stonin-2; Belongs to the Stoned B family. (876 aa)
	N309_11414	Epidermal growth factor receptor substrate 15. (711 aa)
	N309_00899	Phosphatidylinositol-binding clathrin assembly protein. (438 aa)
	N309_03179	Uncharacterized protein FLJ45252. (315 aa)
	N309_05748	Clathrin heavy chain 1. (1662 aa)
	N309_03717	AP complex subunit beta. (955 aa)
	N309_13063	AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family. (433 aa)
	N309_15345	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (161 aa)
	N309_03180	AP2-associated protein kinase 1. (96 aa)
	N309_03797	VPS10 domain-containing receptor SorCS3. (822 aa)
	N309_06604	AP-3 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (382 aa)

Your Current Organism:

Tinamus guttatus

NCBI taxonomy Id: 94827
Other names: T. guttatus, white-throated tinamou

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N309_00261	N309_00646	A0A099ZAC1	A0A099ZIB9	AP-1 complex subunit gamma.	RalBP1-associated Eps domain-containing protein 2.	0.710
N309_00261	N309_00899	A0A099ZAC1	A0A099ZMA8	AP-1 complex subunit gamma.	Phosphatidylinositol-binding clathrin assembly protein.	0.731
N309_00261	N309_01119	A0A099ZAC1	A0A099Z4H2	AP-1 complex subunit gamma.	Clathrin coat assembly protein AP180.	0.731
N309_00261	N309_01816	A0A099ZAC1	A0A099ZAB7	AP-1 complex subunit gamma.	AP-4 complex subunit beta-1.	0.987
N309_00261	N309_02065	A0A099ZAC1	A0A099ZCA4	AP-1 complex subunit gamma.	Epsin-3.	0.801
N309_00261	N309_02298	A0A099ZAC1	A0A099YW61	AP-1 complex subunit gamma.	AP-5 complex subunit mu-1.	0.984
N309_00261	N309_02984	A0A099ZAC1	A0A099Z1F9	AP-1 complex subunit gamma.	Adaptin ear-binding coat-associated protein 1.	0.821
N309_00261	N309_03020	A0A099ZAC1	A0A099Z5J9	AP-1 complex subunit gamma.	Epsin-2.	0.867
N309_00261	N309_03102	A0A099ZAC1	A0A099Z0C8	AP-1 complex subunit gamma.	Intersectin-1.	0.982
N309_00261	N309_03179	A0A099ZAC1	A0A099ZNK7	AP-1 complex subunit gamma.	Uncharacterized protein FLJ45252.	0.668
N309_00261	N309_03180	A0A099ZAC1	A0A099ZT70	AP-1 complex subunit gamma.	AP2-associated protein kinase 1.	0.668
N309_00261	N309_03475	A0A099ZAC1	A0A099YR85	AP-1 complex subunit gamma.	ADP-ribosylation factor-like 5B; Belongs to the small GTPase superfamily. Arf family.	0.808
N309_00261	N309_03717	A0A099ZAC1	A0A099ZPE9	AP-1 complex subunit gamma.	AP complex subunit beta.	0.998
N309_00261	N309_03733	A0A099ZAC1	A0A099Z4M2	AP-1 complex subunit gamma.	AP-3 complex subunit mu-2; Belongs to the adaptor complexes medium subunit family.	0.911
N309_00261	N309_03797	A0A099ZAC1	A0A099ZVS0	AP-1 complex subunit gamma.	VPS10 domain-containing receptor SorCS3.	0.638
N309_00261	N309_04009	A0A099ZAC1	A0A099ZEA8	AP-1 complex subunit gamma.	Proline-serine-threonine phosphatase-interacting protein 2.	0.625
N309_00261	N309_04432	A0A099ZAC1	A0A099ZBY7	AP-1 complex subunit gamma.	BMP-2-inducible protein kinase.	0.668
N309_00261	N309_04720	A0A099ZAC1	A0A099ZJ47	AP-1 complex subunit gamma.	Huntingtin-interacting protein 1-related protein.	0.658
N309_00261	N309_05385	A0A099ZAC1	A0A099Z4W2	AP-1 complex subunit gamma.	Huntingtin.	0.470
N309_00261	N309_05604	A0A099ZAC1	A0A099YZC9	AP-1 complex subunit gamma.	AP-3 complex subunit beta-2.	0.978