(42 nodes) Mixed, incl. ERAD pathway, and Sel1-like repeat network (Tinamus guttatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N309_06051	Ubiquitin fusion degradation protein 1. (306 aa)
	N309_07989	Ubiquilin-1. (531 aa)
	N309_05737	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase. (611 aa)
	N309_12850	Ubiquitin conjugation factor E4 A. (850 aa)
	N309_10962	UBX domain-containing protein 7. (468 aa)
	N309_00234	FAS-associated factor 1. (635 aa)
	N309_13403	E3 ubiquitin-protein ligase RNF185. (193 aa)
	N309_15116	Nuclear protein localization protein 4. (561 aa)
	N309_15697	UV excision repair protein RAD23 B. (356 aa)
	N309_04758	Fidgetin; Belongs to the AAA ATPase family. (749 aa)
	N309_03434	Uncharacterized protein. (127 aa)
	N309_04997	Ataxin-3. (343 aa)
	N309_06525	RING finger protein 145. (674 aa)
	N309_06994	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (811 aa)
	N309_11696	FAS-associated factor 2. (429 aa)
	N309_09495	IQ and AAA domain-containing protein 1. (682 aa)
	N309_05130	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (209 aa)
	N309_01965	E3 ubiquitin-protein ligase synoviolin. (77 aa)
	N309_03702	Nuclear valosin-containing protein-like. (841 aa)
	N309_06100	Ubiquitin-associated domain-containing protein 2. (333 aa)
	N309_09988	Protein sel-1 3. (896 aa)
	N309_14867	NSFL1 cofactor p47. (276 aa)
	N309_10587	Ubiquitin-conjugating enzyme E2 G2; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
	N309_13180	E3 ubiquitin-protein ligase CHFR. (599 aa)
	N309_07701	Protein sel-1 1. (769 aa)
	N309_14814	Putative fidgetin-like 2. (96 aa)
	N309_13915	E3 ubiquitin-protein ligase AMFR. (558 aa)
	N309_02330	Fidgetin-like 1; Belongs to the AAA ATPase family. (691 aa)
	N309_02177	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (249 aa)
	N309_14560	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (239 aa)
	N309_06423	Spermatogenesis-associated protein 5; Belongs to the AAA ATPase family. (680 aa)
	N309_14498	Deubiquitinating protein VCIP135. (1123 aa)
	N309_02104	Phospholipase A-2-activating protein. (783 aa)
	N309_14306	RING finger protein 145. (212 aa)
	N309_00622	Ancient ubiquitous protein 1. (401 aa)
	N309_03142	LRP2-binding protein. (292 aa)
	N309_11542	Ubiquitin thioesterase OTU1. (236 aa)
	N309_07287	Sel1 repeat-containing protein 1B. (216 aa)
	N309_12557	Erlin-2. (290 aa)
	N309_01159	Death ligand signal enhancer. (201 aa)
	N309_00414	UBX domain-containing protein 11. (257 aa)
	N309_06107	UBX domain-containing protein 2B. (269 aa)

Your Current Organism:

Tinamus guttatus

NCBI taxonomy Id: 94827
Other names: T. guttatus, white-throated tinamou

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N309_00234	N309_00414	A0A099YXE1	A0A099ZUU6	FAS-associated factor 1.	UBX domain-containing protein 11.	0.781
N309_00234	N309_01159	A0A099YXE1	A0A099ZUB5	FAS-associated factor 1.	Death ligand signal enhancer.	0.550
N309_00234	N309_01965	A0A099YXE1	A0A099Z9U4	FAS-associated factor 1.	E3 ubiquitin-protein ligase synoviolin.	0.599
N309_00234	N309_02104	A0A099YXE1	A0A099ZPF2	FAS-associated factor 1.	Phospholipase A-2-activating protein.	0.882
N309_00234	N309_02177	A0A099YXE1	A0A099ZMC9	FAS-associated factor 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.652
N309_00234	N309_02330	A0A099YXE1	A0A099ZLD8	FAS-associated factor 1.	Fidgetin-like 1; Belongs to the AAA ATPase family.	0.670
N309_00234	N309_03142	A0A099YXE1	A0A099ZRL4	FAS-associated factor 1.	LRP2-binding protein.	0.550
N309_00234	N309_03434	A0A099YXE1	A0A099Z4L7	FAS-associated factor 1.	Uncharacterized protein.	0.550
N309_00234	N309_03702	A0A099YXE1	A0A099ZE11	FAS-associated factor 1.	Nuclear valosin-containing protein-like.	0.666
N309_00234	N309_04758	A0A099YXE1	A0A099Z3E5	FAS-associated factor 1.	Fidgetin; Belongs to the AAA ATPase family.	0.670
N309_00234	N309_05130	A0A099YXE1	A0A099Z9J9	FAS-associated factor 1.	Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.	0.652
N309_00234	N309_06051	A0A099YXE1	A0A099YUK7	FAS-associated factor 1.	Ubiquitin fusion degradation protein 1.	0.986
N309_00234	N309_06100	A0A099YXE1	A0A099ZF74	FAS-associated factor 1.	Ubiquitin-associated domain-containing protein 2.	0.915
N309_00234	N309_06107	A0A099YXE1	A0A099ZVF4	FAS-associated factor 1.	UBX domain-containing protein 2B.	0.989
N309_00234	N309_06423	A0A099YXE1	A0A099ZNH4	FAS-associated factor 1.	Spermatogenesis-associated protein 5; Belongs to the AAA ATPase family.	0.940
N309_00234	N309_06525	A0A099YXE1	A0A099Z735	FAS-associated factor 1.	RING finger protein 145.	0.599
N309_00234	N309_06994	A0A099YXE1	A0A099Z7K8	FAS-associated factor 1.	Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family.	0.998
N309_00234	N309_07287	A0A099YXE1	A0A099ZT83	FAS-associated factor 1.	Sel1 repeat-containing protein 1B.	0.489
N309_00234	N309_07701	A0A099YXE1	A0A099ZJ56	FAS-associated factor 1.	Protein sel-1 1.	0.550
N309_00234	N309_07989	A0A099YXE1	A0A099YVS3	FAS-associated factor 1.	Ubiquilin-1.	0.416