STRINGSTRING
N309_03720 N309_03720 N309_02246 N309_02246 N309_12407 N309_12407 N309_12957 N309_12957 N309_00071 N309_00071 N309_03272 N309_03272 N309_13689 N309_13689 N309_01664 N309_01664 N309_14602 N309_14602 N309_03587 N309_03587 N309_12297 N309_12297 N309_07597 N309_07597 N309_06941 N309_06941 N309_01136 N309_01136 N309_00384 N309_00384 N309_04060 N309_04060 N309_00320 N309_00320 N309_12450 N309_12450 N309_13638 N309_13638 N309_04398 N309_04398 N309_08401 N309_08401 N309_00482 N309_00482 N309_00738 N309_00738 N309_09438 N309_09438 N309_02040 N309_02040 N309_06833 N309_06833 N309_10846 N309_10846 N309_02020 N309_02020 N309_02602 N309_02602 N309_05271 N309_05271 N309_12588 N309_12588 N309_08300 N309_08300 N309_14432 N309_14432 N309_07009 N309_07009 N309_05295 N309_05295 N309_03636 N309_03636 N309_06669 N309_06669 N309_08707 N309_08707 N309_12274 N309_12274
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
N309_03720DNA repair protein RAD51 4. (303 aa)
N309_02246X-ray repair cross-complementing protein 5. (609 aa)
N309_12407DNA repair protein XRCC3. (347 aa)
N309_12957ATP-dependent DNA helicase; Belongs to the helicase family. (398 aa)
N309_00071Serine/threonine-protein kinase atr. (58 aa)
N309_03272Breast cancer type 2 susceptibility protein. (3384 aa)
N309_13689Structural maintenance of chromosomes protein 6. (1095 aa)
N309_01664Uncharacterized protein. (249 aa)
N309_14602F-box only protein 4. (245 aa)
N309_03587Protein artemis. (657 aa)
N309_12297DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
N309_07597Serine/threonine-protein kinase ATR; Belongs to the PI3/PI4-kinase family. (2661 aa)
N309_06941DNA helicase INO80. (1195 aa)
N309_01136Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (762 aa)
N309_00384Protection of telomeres protein 1. (766 aa)
N309_04060H/ACA ribonucleoprotein complex subunit 4. (459 aa)
N309_00320H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (175 aa)
N309_12450Zinc finger protein 827. (558 aa)
N309_13638RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (409 aa)
N309_04398CST complex subunit CTC1. (116 aa)
N309_08401DNA repair protein RAD50. (1315 aa)
N309_00482INO80 complex subunit D. (929 aa)
N309_00738TP53RK-binding protein; Belongs to the CGI121/TPRKB family. (129 aa)
N309_09438Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1218 aa)
N309_02040Uncharacterized protein. (1076 aa)
N309_06833CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (362 aa)
N309_10846E3 SUMO-protein ligase NSE2. (227 aa)
N309_02020G1/S-specific cyclin-E2; Belongs to the cyclin family. (378 aa)
N309_02602Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (526 aa)
N309_05271Uncharacterized protein. (254 aa)
N309_12588Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (531 aa)
N309_08300Double-strand break repair protein MRE11; Belongs to the MRE11/RAD32 family. (622 aa)
N309_14432Microspherule protein 1. (74 aa)
N309_07009Werner syndrome ATP-dependent helicase. (1357 aa)
N309_05295Regulator of nonsense transcripts 1. (1024 aa)
N309_03636DNA repair protein RAD51 3. (342 aa)
N309_06669X-ray repair cross-complementing protein 5. (730 aa)
N309_08707CS domain-containing protein. (146 aa)
N309_12274Checkpoint protein; Belongs to the HUS1 family. (284 aa)
Your Current Organism:
Tinamus guttatus
NCBI taxonomy Id: 94827
Other names: T. guttatus, white-throated tinamou
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