(133 nodes) Forebrain development network (Tinamus guttatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N309_03491	T-box transcription factor TBX2-B. (559 aa)
	N309_05353	Homeobox protein DLX-1. (245 aa)
	N309_11401	Transcription factor RFX4. (721 aa)
	N309_08105	Amino acid transporter. (423 aa)
	PAFAH1B1	Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration; Belongs to the WD repeat LIS1/nudF family. (410 aa)
	N309_06543	Protein BTG2. (114 aa)
	N309_00290	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1252 aa)
	N309_01644	EF-hand domain-containing protein 1. (601 aa)
	N309_15233	G-protein coupled receptor 56; Belongs to the G-protein coupled receptor 2 family. (544 aa)
	N309_04218	Rap guanine nucleotide exchange factor 2. (448 aa)
	N309_10800	Tetratricopeptide repeat protein 21B. (1286 aa)
	N309_00621	Uncharacterized protein. (58 aa)
	N309_12385	D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (457 aa)
	N309_02080	Oligodendrocyte transcription factor 2. (164 aa)
	N309_12731	Fasciculation and elongation protein zeta-1. (227 aa)
	N309_02061	Oligodendrocyte transcription factor 3. (150 aa)
	N309_04540	Transmembrane protein 108. (357 aa)
	N309_05227	Akirin-2. (124 aa)
	N309_11579	LIM/homeobox protein Lhx3. (322 aa)
	N309_13918	Bardet-Biedl syndrome 2 protein. (682 aa)
	N309_15585	Rho GTPase-activating protein 35. (136 aa)
	N309_02355	Homeobox protein GHOX-7. (148 aa)
	N309_00932	Chromodomain-helicase-DNA-binding protein 8. (80 aa)
	N309_10505	Midkine. (142 aa)
	N309_09526	B-cell lymphoma/leukemia 11B. (864 aa)
	N309_09144	Sal-like 3. (1307 aa)
	N309_08071	Cyclic AMP-responsive element-binding protein 1. (350 aa)
	N309_00438	SUN domain-containing protein 2. (682 aa)
	N309_01527	POU domain protein. (148 aa)
	N309_01269	Homeobox protein EMX2. (247 aa)
	N309_07536	Cytoplasmic dynein 2 heavy chain 1. (670 aa)
	N309_09059	Lysine-specific histone demethylase 1A. (735 aa)
	N309_05142	Crk-like. (299 aa)
	N309_03826	Asparagine--tRNA ligase, cytoplasmic. (545 aa)
	N309_05650	Leucine-rich repeat-containing protein 45. (597 aa)
	N309_06995	T-box brain protein 1. (520 aa)
	N309_08441	Cytosolic carboxypeptidase 1. (986 aa)
	N309_00404	SCL-interrupting locus protein. (1306 aa)
	N309_06398	Nuclear receptor subfamily 4 group A member 2. (204 aa)
	N309_09230	Neuronal migration protein doublecortin. (351 aa)
	N309_05425	Transcription factor SOX-2. (315 aa)
	N309_11907	Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
	N309_11393	Transformer-2 protein beta. (251 aa)
	N309_10443	Patched domain-containing protein 4. (887 aa)
	N309_04259	SH3 and multiple ankyrin repeat domains protein 3. (146 aa)
	N309_09075	Janus kinase and microtubule-interacting protein 3. (830 aa)
	N309_08967	SUN domain-containing protein 1. (873 aa)
	N309_13630	Growth/differentiation factor 6. (307 aa)
	N309_04751	Janus kinase and microtubule-interacting protein 1. (834 aa)
	N309_08874	Macrophage colony-stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (951 aa)
	N309_03385	MAGUK p55 subfamily member 5. (483 aa)
	N309_13278	Neuroendocrine convertase 1; Belongs to the peptidase S8 family. (417 aa)
	N309_14730	Merlin. (524 aa)
	N309_00849	Centrosomal protein of 120 kDa. (975 aa)
	N309_13995	Tectonic-1. (512 aa)
	N309_12025	Homeobox protein goosecoid. (140 aa)
	N309_13808	Janus kinase and microtubule-interacting protein 2. (541 aa)
	N309_06695	LIM/homeobox protein Lhx4. (237 aa)
	N309_13895	SH3 and multiple ankyrin repeat domains protein 3. (995 aa)
	N309_01597	Anion exchange protein. (929 aa)
	N309_14646	Pituitary homeobox 2. (253 aa)
	N309_03950	Zinc finger SWIM domain-containing protein 5. (979 aa)
	N309_01325	Microcephalin. (513 aa)
	N309_04263	Leucine-rich repeat serine/threonine-protein kinase 2. (2452 aa)
	N309_05637	Somatostatin receptor type 1; Belongs to the G-protein coupled receptor 1 family. (360 aa)
	N309_08478	Eomesodermin. (355 aa)
	N309_01248	Protein NDNF. (526 aa)
	N309_03357	Protein numb. (428 aa)
	N309_03359	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (388 aa)
	N309_03390	Neuroendocrine convertase 1. (684 aa)
	N309_04656	Coiled-coil domain-containing protein 85C. (242 aa)
	N309_07375	Fibroblast growth factor receptor substrate 2. (501 aa)
	N309_04679	Forkhead box protein G1. (99 aa)
	N309_14143	Transforming acidic coiled-coil-containing protein 2. (591 aa)
	N309_08187	Zinc finger SWIM domain-containing protein 6. (973 aa)
	N309_13426	Protein fantom. (1274 aa)
	N309_13720	Cystine/glutamate transporter. (467 aa)
	N309_02091	Uncharacterized protein C2orf66. (101 aa)
	N309_08467	Noggin. (216 aa)
	N309_01721	Thymocyte selection-associated high mobility group box protein TOX. (284 aa)
	N309_11646	VIP peptides. (161 aa)
	N309_13011	SUN domain-containing protein 3. (160 aa)
	N309_07735	Peroxisomal membrane protein PEX13. (379 aa)
	N309_13861	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa)
	N309_00248	Patched domain-containing protein 1. (771 aa)
	N309_03221	Sal-like 1. (1306 aa)
	N309_12178	Low-density lipoprotein receptor-related protein 8. (858 aa)
	N309_08153	MADS-box domain-containing protein. (336 aa)
	N309_13739	LIM/homeobox protein Lhx8. (347 aa)
	N309_12876	T-cell acute lymphocytic leukemia protein 2. (109 aa)
	N309_09423	Protein SZT2. (591 aa)
	N309_09424	Protein SZT2. (160 aa)
	N309_06625	Serine/threonine-protein kinase DCLK1. (165 aa)
	N309_06798	Nuclear receptor subfamily 4 group A member 3. (609 aa)
	N309_13445	LIM/homeobox protein Lhx5. (345 aa)
	N309_13836	ADP-ribosylation factor-like 13B. (349 aa)
	N309_12635	Uncharacterized protein C16orf45. (173 aa)
	N309_01394	Aldehyde dehydrogenase family 1 member A3; Belongs to the aldehyde dehydrogenase family. (479 aa)
	N309_15488	Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (279 aa)
	N309_04696	Amyloid beta A4 protein. (756 aa)
	N309_06320	Neurogenic differentiation factor. (337 aa)
	N309_11430	Tyrosine-protein kinase RYK. (277 aa)
	N309_00929	Slit 2 protein. (1154 aa)
	N309_01038	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (852 aa)
	N309_00508	SCY1-like 2. (868 aa)
	N309_13583	Catenin beta-1. (777 aa)
	N309_07438	Merlin. (439 aa)
	N309_07440	Uncharacterized protein. (179 aa)
	N309_07032	Homeobox protein ANF-1. (186 aa)
	N309_08440	Tyrosine-protein kinase receptor. (748 aa)
	N309_05600	Somatostatin receptor type 4; Belongs to the G-protein coupled receptor 1 family. (280 aa)
	N309_04740	Major facilitator superfamily domain-containing protein 2A. (449 aa)
	N309_04220	Protein DPCD. (182 aa)
	N309_08115	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin. (572 aa)
	N309_11263	Proto-oncogene Mas; Belongs to the G-protein coupled receptor 1 family. (329 aa)
	N309_04118	Lymphoid enhancer-binding factor 1. (345 aa)
	N309_15163	Pro-neuregulin-3, membrane-bound isoform. (434 aa)
	N309_00007	Uncharacterized protein. (38 aa)
	N309_05497	Semaphorin-7A. (104 aa)
	N309_04222	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (203 aa)
	N309_15603	Mineralocorticoid receptor. (877 aa)
	N309_05053	Transforming acidic coiled-coil-containing protein 3. (906 aa)
	N309_08112	BTB/POZ domain-containing protein 3. (522 aa)
	N309_04852	Draxin. (308 aa)
	N309_14927	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1208 aa)
	N309_12819	Tetratricopeptide repeat protein 8. (470 aa)
	N309_01629	Cadherin-2; Cadherins are calcium-dependent cell adhesion proteins. (888 aa)
	N309_11618	Protein EURL. (293 aa)
	N309_01289	Cystine/glutamate transporter. (483 aa)
	N309_14845	Bardet-Biedl syndrome 4 protein. (510 aa)
	N309_06426	Transcription factor Sox-3. (205 aa)
	N309_04096	Ninein-like. (98 aa)
	N309_05197	Cholecystokinin receptor type A; Belongs to the G-protein coupled receptor 1 family. (430 aa)

Your Current Organism:

Tinamus guttatus

NCBI taxonomy Id: 94827
Other names: T. guttatus, white-throated tinamou

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N309_00007	N309_07735	A0A099ZUT1	A0A099Z5U7	Uncharacterized protein.	Peroxisomal membrane protein PEX13.	0.546
N309_00290	N309_00929	A0A099ZLV5	A0A099ZBI9	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Slit 2 protein.	0.444
N309_00290	N309_00932	A0A099ZLV5	A0A099ZIM9	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Chromodomain-helicase-DNA-binding protein 8.	0.443
N309_00290	N309_01325	A0A099ZLV5	A0A099Z0J1	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Microcephalin.	0.412
N309_00290	N309_04263	A0A099ZLV5	A0A099Z0N1	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Leucine-rich repeat serine/threonine-protein kinase 2.	0.444
N309_00290	N309_05650	A0A099ZLV5	A0A099ZDW7	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Leucine-rich repeat-containing protein 45.	0.526
N309_00290	N309_11393	A0A099ZLV5	A0A099YUT7	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Transformer-2 protein beta.	0.434
N309_00290	N309_12819	A0A099ZLV5	A0A099ZR51	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Tetratricopeptide repeat protein 8.	0.479
N309_00290	N309_14845	A0A099ZLV5	A0A099ZPY5	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Bardet-Biedl syndrome 4 protein.	0.483
N309_00404	N309_01325	A0A099YQJ4	A0A099Z0J1	SCL-interrupting locus protein.	Microcephalin.	0.564
N309_00404	N309_04222	A0A099YQJ4	A0A099ZU10	SCL-interrupting locus protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.812
N309_00404	N309_04259	A0A099YQJ4	A0A099YVH7	SCL-interrupting locus protein.	SH3 and multiple ankyrin repeat domains protein 3.	0.436
N309_00404	N309_05142	A0A099YQJ4	A0A099ZEB2	SCL-interrupting locus protein.	Crk-like.	0.620
N309_00404	N309_07375	A0A099YQJ4	A0A099Z1U3	SCL-interrupting locus protein.	Fibroblast growth factor receptor substrate 2.	0.758
N309_00404	N309_08440	A0A099YQJ4	A0A099ZDJ5	SCL-interrupting locus protein.	Tyrosine-protein kinase receptor.	0.505
N309_00404	N309_13583	A0A099YQJ4	A0A099ZCF7	SCL-interrupting locus protein.	Catenin beta-1.	0.499
N309_00404	N309_13895	A0A099YQJ4	A0A099YYM0	SCL-interrupting locus protein.	SH3 and multiple ankyrin repeat domains protein 3.	0.436
N309_00438	N309_08967	A0A099ZH05	A0A099YVU2	SUN domain-containing protein 2.	SUN domain-containing protein 1.	0.805
N309_00621	N309_07735	A0A099ZLB0	A0A099Z5U7	Uncharacterized protein.	Peroxisomal membrane protein PEX13.	0.546
N309_00849	N309_04096	A0A099YX36	A0A099ZPA3	Centrosomal protein of 120 kDa.	Ninein-like.	0.407