(56 nodes) Regulation of cold-induced thermogenesis network (Tinamus guttatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N309_15180	Phosphatidylethanolamine N-methyltransferase. (187 aa)
	N309_00784	Adiponectin receptor protein 2. (385 aa)
	N309_03187	Placenta-specific 8. (111 aa)
	N309_07934	Growth arrest and DNA damage-inducible protein GADD45 gamma. (84 aa)
	N309_15172	Dehydrogenase/reductase SDR family member 7B; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (322 aa)
	N309_05030	Paired mesoderm homeobox protein 2B. (141 aa)
	N309_15111	Retinoblastoma-associated protein. (849 aa)
	N309_10355	5'-AMP-activated protein kinase subunit beta-2. (274 aa)
	N309_03768	Endothelial PAS domain-containing protein 1. (59 aa)
	N309_05581	Peptidase_M48 domain-containing protein. (450 aa)
	N309_09619	Chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (347 aa)
	N309_07765	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha. (781 aa)
	N309_08739	Acyl-coenzyme A thioesterase 13. (140 aa)
	N309_07508	PR domain zinc finger protein 16. (110 aa)
	N309_07509	PR domain zinc finger protein 16. (968 aa)
	N309_01844	G0/G1 switch protein 2. (98 aa)
	N309_14701	A disintegrin and metalloproteinase with thrombospondin motifs 5. (657 aa)
	N309_10641	Mitofusin-2. (519 aa)
	N309_13661	DCC-interacting protein 13-beta. (607 aa)
	N309_00448	Cyclic AMP-dependent transcription factor ATF-4. (355 aa)
	N309_07099	Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (50 aa)
	N309_10896	Uncharacterized protein. (466 aa)
	N309_00526	Laminin subunit alpha-4. (1823 aa)
	N309_14819	Appetite-regulating hormone. (123 aa)
	N309_09059	Lysine-specific histone demethylase 1A. (735 aa)
	TSHR	Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (585 aa)
	N309_02866	Mesotocin-neurophysin MT; Belongs to the vasopressin/oxytocin family. (105 aa)
	N309_10835	Interleukin-18 receptor 1. (538 aa)
	N309_06227	Adiponectin. (204 aa)
	N309_00017	Cell death activator CIDE-A. (52 aa)
	N309_11962	Leucine-rich repeat-containing G-protein coupled receptor 4. (727 aa)
	N309_10291	Kinase; Belongs to the inositol phosphokinase (IPK) family. (433 aa)
	N309_02701	Alstrom syndrome protein 1. (261 aa)
	N309_04119	Uncharacterized protein. (243 aa)
	N309_09594	Uncharacterized protein. (226 aa)
	N309_12567	Adiponectin receptor protein 1. (302 aa)
	N309_02703	Alstrom syndrome protein 1. (356 aa)
	N309_02702	Uncharacterized protein. (60 aa)
	N309_08385	NAD-dependent protein deacetylase sirtuin-6. (336 aa)
	N309_08584	Oxysterols receptor LXR-alpha. (409 aa)
	N309_02699	Alstrom syndrome protein 1. (156 aa)
	N309_05450	Cell death activator CIDE-A. (160 aa)
	N309_03596	Endothelial PAS domain-containing protein 1. (802 aa)
	N309_13602	Interleukin; Belongs to the IL-15/IL-21 family. (163 aa)
	N309_01135	Uncharacterized protein. (313 aa)
	N309_04632	MDS1 and EVI1 complex locus protein MDS1. (117 aa)
	N309_15068	Solute carrier family 25 member 44; Belongs to the mitochondrial carrier (TC 2.A.29) family. (315 aa)
	N309_11120	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (116 aa)
	N309_09844	Interleukin-18. (194 aa)
	N309_12995	Free fatty acid receptor 4. (335 aa)
	N309_05399	Zinc finger protein 423. (1195 aa)
	N309_08801	Transient receptor potential cation channel subfamily V member 2. (713 aa)
	N309_02803	Monoacylglycerol lipase ABHD6. (337 aa)
	N309_15660	Atrial natriuretic peptide receptor 3. (188 aa)
	N309_03188	Placenta-specific 8. (90 aa)
	N309_15175	Folliculin. (581 aa)

Your Current Organism:

Tinamus guttatus

NCBI taxonomy Id: 94827
Other names: T. guttatus, white-throated tinamou

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N309_00526	N309_08385	A0A099ZCF6	A0A099ZP49	Laminin subunit alpha-4.	NAD-dependent protein deacetylase sirtuin-6.	0.420
N309_00784	N309_06227	A0A099YY05	A0A099ZV78	Adiponectin receptor protein 2.	Adiponectin.	0.920
N309_00784	N309_12567	A0A099YY05	A0A099ZPX6	Adiponectin receptor protein 2.	Adiponectin receptor protein 1.	0.826
N309_00784	N309_13661	A0A099YY05	A0A099ZB26	Adiponectin receptor protein 2.	DCC-interacting protein 13-beta.	0.908
N309_01135	N309_04119	A0A099ZIW1	A0A099ZS40	Uncharacterized protein.	Uncharacterized protein.	0.690
N309_02699	N309_02701	A0A099ZMH9	A0A099ZSC7	Alstrom syndrome protein 1.	Alstrom syndrome protein 1.	0.725
N309_02699	N309_02703	A0A099ZMH9	A0A099ZPE4	Alstrom syndrome protein 1.	Alstrom syndrome protein 1.	0.523
N309_02701	N309_02699	A0A099ZSC7	A0A099ZMH9	Alstrom syndrome protein 1.	Alstrom syndrome protein 1.	0.725
N309_02701	N309_02703	A0A099ZSC7	A0A099ZPE4	Alstrom syndrome protein 1.	Alstrom syndrome protein 1.	0.782
N309_02703	N309_02699	A0A099ZPE4	A0A099ZMH9	Alstrom syndrome protein 1.	Alstrom syndrome protein 1.	0.523
N309_02703	N309_02701	A0A099ZPE4	A0A099ZSC7	Alstrom syndrome protein 1.	Alstrom syndrome protein 1.	0.782
N309_02866	N309_12995	A0A099ZGB4	A0A099YZY6	Mesotocin-neurophysin MT; Belongs to the vasopressin/oxytocin family.	Free fatty acid receptor 4.	0.410
N309_02866	N309_14819	A0A099ZGB4	A0A099ZE13	Mesotocin-neurophysin MT; Belongs to the vasopressin/oxytocin family.	Appetite-regulating hormone.	0.603
N309_03187	N309_07765	A0A099YXQ2	A0A099Z498	Placenta-specific 8.	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha.	0.434
N309_03188	N309_07765	A0A099YZC7	A0A099Z498	Placenta-specific 8.	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha.	0.434
N309_03596	N309_08385	A0A099ZLR8	A0A099ZP49	Endothelial PAS domain-containing protein 1.	NAD-dependent protein deacetylase sirtuin-6.	0.697
N309_03768	N309_08385	A0A099YQL5	A0A099ZP49	Endothelial PAS domain-containing protein 1.	NAD-dependent protein deacetylase sirtuin-6.	0.697
N309_04119	N309_01135	A0A099ZS40	A0A099ZIW1	Uncharacterized protein.	Uncharacterized protein.	0.690
N309_04119	N309_08739	A0A099ZS40	A0A099Z7W7	Uncharacterized protein.	Acyl-coenzyme A thioesterase 13.	0.497
N309_04119	N309_10896	A0A099ZS40	A0A099ZBQ2	Uncharacterized protein.	Uncharacterized protein.	0.559