(42 nodes) TCR signaling network (Tinamus guttatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N309_11764	Mitogen-activated protein kinase kinase kinase 7. (585 aa)
	N309_02288	IGv domain-containing protein. (81 aa)
	N309_00082	Serine/threonine-protein kinase PAK 1. (59 aa)
	N309_15464	Phosphatidylinositol 3-kinase regulatory subunit beta. (550 aa)
	N309_01149	F-box/WD repeat-containing protein 11. (552 aa)
	N309_05849	Receptor-type tyrosine-protein phosphatase C. (1219 aa)
	N309_07610	Receptor-type tyrosine-protein phosphatase eta. (1145 aa)
	N309_09396	26S proteasome non-ATPase regulatory subunit 1. (951 aa)
	N309_02962	Receptor-interacting serine/threonine-protein kinase 2. (201 aa)
	N309_11175	Non-specific serine/threonine protein kinase. (527 aa)
	N309_11570	Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (212 aa)
	N309_02885	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family. (1069 aa)
	N309_08110	TNF receptor-associated factor 6. (544 aa)
	N309_10368	annotation not available (376 aa)
	N309_09302	Proteasome endopeptidase complex. (216 aa)
	N309_01281	3-phosphoinositide-dependent protein kinase 1. (514 aa)
	N309_07175	Mitogen-activated protein kinase kinase kinase MLT. (798 aa)
	N309_06070	Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1. (1177 aa)
	N309_13509	S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
	N309_09497	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1. (298 aa)
	N309_03830	Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (222 aa)
	N309_05665	Polyubiquitin-C. (228 aa)
	N309_13141	Ubiquitin-conjugating enzyme E2 variant 1. (221 aa)
	N309_06819	T-cell surface glycoprotein CD3 zeta chain. (126 aa)
	N309_10738	Ubiquitin-40S ribosomal protein S27a. (158 aa)
	N309_12915	Nuclear factor NF-kappa-B p105 subunit. (880 aa)
	N309_03061	T-cell surface glycoprotein CD3 epsilon chain. (177 aa)
	N309_08946	Non-specific protein-tyrosine kinase. (615 aa)
	N309_10601	H-2 class II histocompatibility antigen, A-Q beta chain. (112 aa)
	N309_05460	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2. (698 aa)
	N309_15195	Cullin-1; Belongs to the cullin family. (785 aa)
	N309_00346	KxDL motif-containing protein 1. (141 aa)
	N309_10751	Receptor-interacting serine/threonine-protein kinase 2. (510 aa)
	N309_02418	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (91 aa)
	N309_09801	Phosphoinositide phospholipase C. (1092 aa)
	N309_12073	26S proteasome non-ATPase regulatory subunit 10. (189 aa)
	N309_14089	T-cell surface glycoprotein CD4. (400 aa)
	N309_10880	Non-specific serine/threonine protein kinase. (547 aa)
	N309_05622	Mucosa-associated lymphoid tissue lymphoma translocation protein 1. (222 aa)
	N309_03088	B-cell lymphoma/leukemia 10. (219 aa)
	N309_09232	Serine/threonine-protein kinase PAK 3; Belongs to the protein kinase superfamily. (383 aa)
	N309_12127	Phosphoinositide phospholipase C. (997 aa)

Your Current Organism:

Tinamus guttatus

NCBI taxonomy Id: 94827
Other names: T. guttatus, white-throated tinamou

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N309_00082	N309_02418	A0A099ZV88	A0A099Z5P5	Serine/threonine-protein kinase PAK 1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family.	0.495
N309_00082	N309_02885	A0A099ZV88	A0A099ZMR4	Serine/threonine-protein kinase PAK 1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family.	0.453
N309_00082	N309_07175	A0A099ZV88	A0A099ZIF3	Serine/threonine-protein kinase PAK 1.	Mitogen-activated protein kinase kinase kinase MLT.	0.407
N309_00082	N309_08946	A0A099ZV88	A0A099Z8T8	Serine/threonine-protein kinase PAK 1.	Non-specific protein-tyrosine kinase.	0.510
N309_00082	N309_09801	A0A099ZV88	A0A099Z5M8	Serine/threonine-protein kinase PAK 1.	Phosphoinositide phospholipase C.	0.542
N309_00082	N309_11175	A0A099ZV88	A0A099ZNZ4	Serine/threonine-protein kinase PAK 1.	Non-specific serine/threonine protein kinase.	0.755
N309_00082	N309_11764	A0A099ZV88	A0A099ZLV2	Serine/threonine-protein kinase PAK 1.	Mitogen-activated protein kinase kinase kinase 7.	0.429
N309_00082	N309_12127	A0A099ZV88	A0A099YV34	Serine/threonine-protein kinase PAK 1.	Phosphoinositide phospholipase C.	0.541
N309_00082	N309_15464	A0A099ZV88	A0A099ZUP0	Serine/threonine-protein kinase PAK 1.	Phosphatidylinositol 3-kinase regulatory subunit beta.	0.421
N309_00346	N309_05665	A0A099Z7V5	A0A099ZFY2	KxDL motif-containing protein 1.	Polyubiquitin-C.	0.743
N309_00346	N309_10738	A0A099Z7V5	A0A099ZB74	KxDL motif-containing protein 1.	Ubiquitin-40S ribosomal protein S27a.	0.857
N309_01149	N309_05665	A0A099ZUA4	A0A099ZFY2	F-box/WD repeat-containing protein 11.	Polyubiquitin-C.	0.793
N309_01149	N309_10738	A0A099ZUA4	A0A099ZB74	F-box/WD repeat-containing protein 11.	Ubiquitin-40S ribosomal protein S27a.	0.738
N309_01149	N309_12915	A0A099ZUA4	A0A099ZB38	F-box/WD repeat-containing protein 11.	Nuclear factor NF-kappa-B p105 subunit.	0.825
N309_01149	N309_13509	A0A099ZUA4	A0A099ZGX0	F-box/WD repeat-containing protein 11.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.996
N309_01149	N309_15195	A0A099ZUA4	A0A099Z853	F-box/WD repeat-containing protein 11.	Cullin-1; Belongs to the cullin family.	0.989
N309_01281	N309_02418	A0A099ZIY5	A0A099Z5P5	3-phosphoinositide-dependent protein kinase 1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family.	0.865
N309_01281	N309_02885	A0A099ZIY5	A0A099ZMR4	3-phosphoinositide-dependent protein kinase 1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family.	0.865
N309_01281	N309_02962	A0A099ZIY5	A0A099ZPM8	3-phosphoinositide-dependent protein kinase 1.	Receptor-interacting serine/threonine-protein kinase 2.	0.646
N309_01281	N309_05460	A0A099ZIY5	A0A099Z8F0	3-phosphoinositide-dependent protein kinase 1.	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2.	0.559