(23 nodes) G1/S DNA Damage Checkpoints network (Tinamus guttatus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N309_05402	Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily. (322 aa)
	N309_00009	Uncharacterized protein. (39 aa)
	N309_12258	Cyclin-A2; Belongs to the cyclin family. (280 aa)
	N309_09396	26S proteasome non-ATPase regulatory subunit 1. (951 aa)
	N309_14214	Zinc finger protein 385B. (382 aa)
	N309_06685	E3 ubiquitin-protein ligase RFWD2. (580 aa)
	N309_00706	Cyclin-dependent kinase inhibitor 1B. (48 aa)
	N309_12073	26S proteasome non-ATPase regulatory subunit 10. (189 aa)
	N309_04525	Serine/threonine-protein kinase Chk2. (458 aa)
	N309_00708	Cyclin-dependent kinase inhibitor 1B. (198 aa)
	N309_00346	KxDL motif-containing protein 1. (141 aa)
	N309_10738	Ubiquitin-40S ribosomal protein S27a. (158 aa)
	N309_12355	Cyclin-A1; Belongs to the cyclin family. (364 aa)
	N309_04144	E3 ubiquitin-protein ligase Mdm2. (486 aa)
	N309_15634	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (478 aa)
	N309_09302	Proteasome endopeptidase complex. (216 aa)
	N309_03761	Zinc finger protein 385B. (96 aa)
	N309_07156	G1/S-specific cyclin-E1; Belongs to the cyclin family. (380 aa)
	N309_05665	Polyubiquitin-C. (228 aa)
	N309_13527	26S protease regulatory subunit 4; Belongs to the AAA ATPase family. (439 aa)
	N309_00329	Proteasome activator complex subunit 3. (157 aa)
	N309_02020	G1/S-specific cyclin-E2; Belongs to the cyclin family. (378 aa)
	N309_02167	Cyclin-dependent kinase inhibitor 1. (54 aa)

Your Current Organism:

Tinamus guttatus

NCBI taxonomy Id: 94827
Other names: T. guttatus, white-throated tinamou

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N309_00009	N309_00329	A0A099ZWR8	A0A099YXY8	Uncharacterized protein.	Proteasome activator complex subunit 3.	0.677
N309_00009	N309_02020	A0A099ZWR8	A0A099YZ19	Uncharacterized protein.	G1/S-specific cyclin-E2; Belongs to the cyclin family.	0.921
N309_00009	N309_04144	A0A099ZWR8	A0A099ZMI0	Uncharacterized protein.	E3 ubiquitin-protein ligase Mdm2.	0.480
N309_00009	N309_05402	A0A099ZWR8	A0A099Z9I5	Uncharacterized protein.	Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily.	0.855
N309_00009	N309_05665	A0A099ZWR8	A0A099ZFY2	Uncharacterized protein.	Polyubiquitin-C.	0.790
N309_00009	N309_07156	A0A099ZWR8	A0A099ZH74	Uncharacterized protein.	G1/S-specific cyclin-E1; Belongs to the cyclin family.	0.922
N309_00009	N309_09302	A0A099ZWR8	A0A099ZJM5	Uncharacterized protein.	Proteasome endopeptidase complex.	0.592
N309_00009	N309_10738	A0A099ZWR8	A0A099ZB74	Uncharacterized protein.	Ubiquitin-40S ribosomal protein S27a.	0.789
N309_00009	N309_12073	A0A099ZWR8	A0A099Z585	Uncharacterized protein.	26S proteasome non-ATPase regulatory subunit 10.	0.420
N309_00009	N309_12258	A0A099ZWR8	A0A099ZUF7	Uncharacterized protein.	Cyclin-A2; Belongs to the cyclin family.	0.907
N309_00009	N309_12355	A0A099ZWR8	A0A099ZNJ7	Uncharacterized protein.	Cyclin-A1; Belongs to the cyclin family.	0.891
N309_00009	N309_13527	A0A099ZWR8	A0A099YWF2	Uncharacterized protein.	26S protease regulatory subunit 4; Belongs to the AAA ATPase family.	0.553
N309_00009	N309_15634	A0A099ZWR8	A0A099ZM81	Uncharacterized protein.	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.	0.417
N309_00329	N309_00009	A0A099YXY8	A0A099ZWR8	Proteasome activator complex subunit 3.	Uncharacterized protein.	0.677
N309_00329	N309_00706	A0A099YXY8	A0A099Z4P8	Proteasome activator complex subunit 3.	Cyclin-dependent kinase inhibitor 1B.	0.677
N309_00329	N309_00708	A0A099YXY8	A0A099Z6S3	Proteasome activator complex subunit 3.	Cyclin-dependent kinase inhibitor 1B.	0.677
N309_00329	N309_02167	A0A099YXY8	A0A099YZ37	Proteasome activator complex subunit 3.	Cyclin-dependent kinase inhibitor 1.	0.677
N309_00329	N309_05402	A0A099YXY8	A0A099Z9I5	Proteasome activator complex subunit 3.	Cyclin-dependent kinase 3; Belongs to the protein kinase superfamily.	0.570
N309_00329	N309_05665	A0A099YXY8	A0A099ZFY2	Proteasome activator complex subunit 3.	Polyubiquitin-C.	0.644
N309_00329	N309_09302	A0A099YXY8	A0A099ZJM5	Proteasome activator complex subunit 3.	Proteasome endopeptidase complex.	0.990