(85 nodes) Ribosome biogenesis in eukaryotes network (Tinamus guttatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N309_08868	Treacle domain-containing protein. (412 aa)
	N309_11653	Ribonuclease P protein subunit p38. (281 aa)
	N309_02435	Ribonuclease P protein subunit p40. (322 aa)
	N309_09202	Bromodomain-containing protein 4. (439 aa)
	N309_11900	Nucleolar protein 6. (884 aa)
	N309_13748	RNA-binding protein NOB1. (302 aa)
	N309_13866	HEAT repeat-containing protein 1. (2162 aa)
	N309_07132	Treslin. (216 aa)
	N309_07133	Treslin. (707 aa)
	N309_10007	WD repeat-containing protein 43. (597 aa)
	N309_07894	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (488 aa)
	N309_13878	Nucleolar GTP-binding protein 1. (618 aa)
	N309_14077	Ribosomal RNA small subunit methyltransferase NEP1. (188 aa)
	N309_15231	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (391 aa)
	N309_05893	Protein FAM134A. (478 aa)
	N309_07414	Exportin-1. (1073 aa)
	N309_04384	Ribosomal RNA-processing protein 7 A. (210 aa)
	N309_08434	Eukaryotic translation initiation factor 6. (206 aa)
	N309_04480	Ribonuclease P protein subunit p29. (199 aa)
	N309_07558	Deoxynucleotidyltransferase terminal-interacting protein 2. (713 aa)
	N309_05942	Uncharacterized protein KIAA2026. (1274 aa)
	N309_05952	RNA 3'-terminal phosphate cyclase-like. (329 aa)
	N309_05544	Transducin beta-like 3. (808 aa)
	N309_11524	WD repeat-containing protein 3. (934 aa)
	N309_08610	rRNA-processing protein FCF1. (150 aa)
	N309_14335	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (139 aa)
	N309_06761	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (217 aa)
	AK6	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily. (171 aa)
	N309_11076	U3 small nucleolar RNA-associated protein 18. (473 aa)
	N309_05941	Uncharacterized protein KIAA2026. (502 aa)
	N309_09140	U3 small nucleolar RNA-associated protein 6. (595 aa)
	N309_09762	Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (315 aa)
	N309_03702	Nuclear valosin-containing protein-like. (841 aa)
	N309_13247	Transmembrane protein 120B. (317 aa)
	N309_13945	Uncharacterized protein. (50 aa)
	N309_09084	Putative tRNA pseudouridine synthase 1. (240 aa)
	N309_06760	Putative G-protein coupled receptor 133. (481 aa)
	N309_09803	Von Willebrand factor C domain-containing protein 2-like. (222 aa)
	N309_07598	5'-3' exoribonuclease 1. (1692 aa)
	N309_13942	Periodic tryptophan protein 2. (879 aa)
	N309_13634	Protein FAM134C. (342 aa)
	N309_14460	Ribonuclease P protein subunit p30. (240 aa)
	N309_02334	Brorin. (177 aa)
	N309_08063	Nucleolar protein 58. (516 aa)
	N309_09455	Serine/threonine-protein kinase RIO1. (449 aa)
	N309_11124	WD repeat-containing protein 36. (840 aa)
	N309_03750	Putative RNA exonuclease NEF-sp. (736 aa)
	N309_11634	Ribosome biogenesis protein BMS1. (1274 aa)
	N309_02465	Colorectal mutant cancer protein. (962 aa)
	N309_10102	RNA exonuclease 1. (1172 aa)
	N309_08022	Protein FAM134B. (407 aa)
	N309_13668	Methyltransferase-like 9. (263 aa)
	N309_12826	Bromodomain-containing protein 4. (185 aa)
	N309_03456	NTF2-related export protein 2. (142 aa)
	N309_03325	Large subunit GTPase 1. (591 aa)
	N309_04125	Elongation factor Tu GTP-binding domain-containing protein 1. (1072 aa)
	N309_08417	Rho GTPase-activating protein 26. (695 aa)
	N309_09510	U3 small nucleolar ribonucleoprotein MPP10. (644 aa)
	N309_08021	Zinc finger protein 622. (471 aa)
	N309_11826	Ceramide-1-phosphate transfer protein. (107 aa)
	N309_10669	U3 small nucleolar RNA-associated protein 15. (493 aa)
	N309_15125	Ribonuclease P protein subunit p25-like. (138 aa)
	N309_05995	Transmembrane protein 120A. (318 aa)
	N309_06596	UPF0235 protein C15orf40. (74 aa)
	N309_03841	Ribonuclease 3. (819 aa)
	N309_14044	U3 small nucleolar RNA-associated protein 15. (497 aa)
	N309_08961	WD repeat-containing protein 75. (761 aa)
	N309_13081	Bromodomain testis-specific protein. (960 aa)
	N309_15455	Ribonuclease P protein subunit p25-like. (138 aa)
	N309_14676	U3 small nucleolar RNA-associated protein 14 A. (641 aa)
	N309_14623	5'-3' exoribonuclease 2. (895 aa)
	N309_06423	Spermatogenesis-associated protein 5; Belongs to the AAA ATPase family. (680 aa)
	N309_02245	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (127 aa)
	N309_08779	Ribonuclease P protein subunit p25. (138 aa)
	N309_11910	Bromodomain-containing protein 3. (722 aa)
	N309_08990	Exonuclease domain-containing protein. (170 aa)
	N309_01056	Protein kish; Involved in the early part of the secretory pathway. (37 aa)
	N309_04060	H/ACA ribonucleoprotein complex subunit 4. (459 aa)
	N309_00320	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (175 aa)
	N309_07263	Guanine nucleotide-binding protein-like 3. (565 aa)
	N309_13055	Ribosome maturation protein SBDS. (165 aa)
	N309_01185	Uncharacterized protein. (47 aa)
	N309_09476	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (637 aa)
	N309_00157	Ribonuclease P protein subunit p38. (281 aa)
	N309_15123	Rho GTPase-activating protein 42. (629 aa)

Your Current Organism:

Tinamus guttatus

NCBI taxonomy Id: 94827
Other names: T. guttatus, white-throated tinamou

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK6	N309_04480	A0A099ZD57	A0A099Z8C0	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	Ribonuclease P protein subunit p29.	0.443
AK6	N309_08610	A0A099ZD57	A0A099ZBQ7	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	rRNA-processing protein FCF1.	0.410
AK6	N309_09455	A0A099ZD57	A0A099ZHS3	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	Serine/threonine-protein kinase RIO1.	0.617
AK6	N309_10007	A0A099ZD57	A0A099Z358	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	WD repeat-containing protein 43.	0.446
AK6	N309_11634	A0A099ZD57	A0A099YW82	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	Ribosome biogenesis protein BMS1.	0.569
AK6	N309_13748	A0A099ZD57	A0A099Z0G5	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	RNA-binding protein NOB1.	0.680
AK6	N309_13866	A0A099ZD57	A0A099Z144	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	HEAT repeat-containing protein 1.	0.447
AK6	N309_13942	A0A099ZD57	A0A099ZGF1	Adenylate kinase isoenzyme 6; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation; Belongs to the adenylate kinase family. AK6 subfamily.	Periodic tryptophan protein 2.	0.477
N309_00157	N309_00320	A0A099ZVG6	A0A099ZRH1	Ribonuclease P protein subunit p38.	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.	0.916
N309_00157	N309_02435	A0A099ZVG6	A0A099YZL3	Ribonuclease P protein subunit p38.	Ribonuclease P protein subunit p40.	0.933
N309_00157	N309_02465	A0A099ZVG6	A0A099YVN9	Ribonuclease P protein subunit p38.	Colorectal mutant cancer protein.	0.664
N309_00157	N309_03325	A0A099ZVG6	A0A099YTI3	Ribonuclease P protein subunit p38.	Large subunit GTPase 1.	0.501
N309_00157	N309_03841	A0A099ZVG6	A0A099ZKZ8	Ribonuclease P protein subunit p38.	Ribonuclease 3.	0.428
N309_00157	N309_04060	A0A099ZVG6	A0A099ZRD2	Ribonuclease P protein subunit p38.	H/ACA ribonucleoprotein complex subunit 4.	0.876
N309_00157	N309_04125	A0A099ZVG6	A0A099YQQ8	Ribonuclease P protein subunit p38.	Elongation factor Tu GTP-binding domain-containing protein 1.	0.770
N309_00157	N309_04384	A0A099ZVG6	A0A099Z6M7	Ribonuclease P protein subunit p38.	Ribosomal RNA-processing protein 7 A.	0.928
N309_00157	N309_04480	A0A099ZVG6	A0A099Z8C0	Ribonuclease P protein subunit p38.	Ribonuclease P protein subunit p29.	0.990
N309_00157	N309_05544	A0A099ZVG6	A0A099ZA08	Ribonuclease P protein subunit p38.	Transducin beta-like 3.	0.895
N309_00157	N309_05893	A0A099ZVG6	A0A099Z5G1	Ribonuclease P protein subunit p38.	Protein FAM134A.	0.431
N309_00157	N309_05952	A0A099ZVG6	A0A099Z965	Ribonuclease P protein subunit p38.	RNA 3'-terminal phosphate cyclase-like.	0.664