(62 nodes) Notch signaling pathway network (Tinamus guttatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N309_12724	Gamma-secretase subunit APH-1A. (214 aa)
	N309_08210	Recombining binding protein suppressor of hairless-like. (432 aa)
	N309_04459	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1203 aa)
	N309_12721	Hairy/enhancer-of-split related with YRPW motif protein 1. (222 aa)
	N309_06230	Von Willebrand factor D and EGF domain-containing protein. (504 aa)
	N309_15693	Putative E3 ubiquitin-protein ligase DTX2. (594 aa)
	N309_13704	Transducin-like enhancer protein 2. (729 aa)
	N309_13703	Amino-terminal enhancer of split. (178 aa)
	N309_08683	Nuclear receptor coactivator 7. (149 aa)
	N309_06232	Von Willebrand factor D and EGF domain-containing protein. (138 aa)
	N309_07187	Histone acetyltransferase KAT2B. (710 aa)
	N309_13953	Histone acetyltransferase KAT2A. (719 aa)
	N309_06229	Von Willebrand factor D and EGF domain-containing protein. (472 aa)
	N309_03806	Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe. (230 aa)
	N309_06231	Von Willebrand factor D and EGF domain-containing protein. (155 aa)
	N309_11032	Protein eyes shut. (391 aa)
	N309_08113	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1193 aa)
	N309_01167	Histone deacetylase 3. (410 aa)
	N309_11552	Mastermind-like 2. (472 aa)
	N309_02966	CREB-binding protein. (2401 aa)
	N309_03871	Histone deacetylase 8. (330 aa)
	N309_10452	Von Willebrand factor D and EGF domain-containing protein. (520 aa)
	N309_08001	Ataxin-1. (802 aa)
	N309_09168	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (458 aa)
	N309_14331	Protein canopy 3. (115 aa)
	N309_01462	Histone deacetylase 1. (440 aa)
	N309_01082	C-terminal-binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (417 aa)
	N309_00262	Ataxin-1-like. (554 aa)
	N309_03357	Protein numb. (428 aa)
	N309_03359	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (388 aa)
	N309_12771	Uncharacterized protein. (101 aa)
	N309_02879	Neurogenic locus notch protein 2. (557 aa)
	N309_04182	Nicastrin. (654 aa)
	N309_14028	C-terminal-binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (375 aa)
	N309_02095	Oxidation resistance protein 1. (150 aa)
	N309_02921	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (665 aa)
	N309_11337	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (604 aa)
	N309_11551	Mastermind-like 2. (433 aa)
	N309_00390	Transducin-like enhancer protein 4. (725 aa)
	N309_15580	Protein eyes shut. (185 aa)
	N309_09546	Receptor-type tyrosine-protein phosphatase epsilon. (618 aa)
	N309_05653	Beta-1,3-N-acetylglucosaminyltransferase radical fringe. (216 aa)
	N309_05220	C-terminal-binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (413 aa)
	N309_08074	Transcription cofactor HES-6. (207 aa)
	N309_09582	Mastermind-like 3. (927 aa)
	N309_08548	Transducin-like enhancer protein 1. (729 aa)
	N309_05795	Segment polarity protein dishevelled DVL-1. (63 aa)
	N309_11827	Segment polarity protein dishevelled DVL-1. (465 aa)
	N309_02753	Histone deacetylase 2. (477 aa)
	N309_08363	Receptor-type tyrosine-protein phosphatase kappa. (367 aa)
	N309_09925	Neurogenic locus notch protein 1. (380 aa)
	N309_12792	Protein eyes shut. (230 aa)
	N309_05196	Suppressor of hairless protein. (468 aa)
	N309_15037	Disintegrin and metalloproteinase domain-containing protein 17. (792 aa)
	N309_08364	Receptor-type tyrosine-protein phosphatase alpha. (91 aa)
	N309_04775	Beta-1,3-N-acetylglucosaminyltransferase. (351 aa)
	N309_14204	SNW domain-containing protein 1. (538 aa)
	N309_03570	Transcription factor HES-5. (160 aa)
	N309_07194	Protein FAM188A. (420 aa)
	N309_13976	Corepressor interacting with RBPJ 1. (304 aa)
	N309_02051	Transducin-like enhancer protein 3. (702 aa)
	N309_06896	E3 ubiquitin-protein ligase DTX3L. (672 aa)

Your Current Organism:

Tinamus guttatus

NCBI taxonomy Id: 94827
Other names: T. guttatus, white-throated tinamou

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N309_00262	N309_05196	A0A099ZCB5	A0A099ZLU4	Ataxin-1-like.	Suppressor of hairless protein.	0.864
N309_00262	N309_08001	A0A099ZCB5	A0A099ZAU1	Ataxin-1-like.	Ataxin-1.	0.872
N309_00262	N309_08210	A0A099ZCB5	A0A099YUL3	Ataxin-1-like.	Recombining binding protein suppressor of hairless-like.	0.857
N309_00390	N309_01082	A0A099ZUT8	A0A099ZB48	Transducin-like enhancer protein 4.	C-terminal-binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.573
N309_00390	N309_01167	A0A099ZUT8	A0A099ZW53	Transducin-like enhancer protein 4.	Histone deacetylase 3.	0.649
N309_00390	N309_01462	A0A099ZUT8	A0A099ZB17	Transducin-like enhancer protein 4.	Histone deacetylase 1.	0.649
N309_00390	N309_02753	A0A099ZUT8	A0A099ZJP0	Transducin-like enhancer protein 4.	Histone deacetylase 2.	0.649
N309_00390	N309_02966	A0A099ZUT8	A0A099ZAD6	Transducin-like enhancer protein 4.	CREB-binding protein.	0.625
N309_00390	N309_03570	A0A099ZUT8	A0A099ZS02	Transducin-like enhancer protein 4.	Transcription factor HES-5.	0.406
N309_00390	N309_03871	A0A099ZUT8	A0A099ZAM0	Transducin-like enhancer protein 4.	Histone deacetylase 8.	0.649
N309_00390	N309_05196	A0A099ZUT8	A0A099ZLU4	Transducin-like enhancer protein 4.	Suppressor of hairless protein.	0.657
N309_00390	N309_05220	A0A099ZUT8	A0A099ZDP7	Transducin-like enhancer protein 4.	C-terminal-binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.573
N309_00390	N309_08074	A0A099ZUT8	A0A099ZFD0	Transducin-like enhancer protein 4.	Transcription cofactor HES-6.	0.645
N309_00390	N309_08210	A0A099ZUT8	A0A099YUL3	Transducin-like enhancer protein 4.	Recombining binding protein suppressor of hairless-like.	0.657
N309_00390	N309_12721	A0A099ZUT8	A0A099YV28	Transducin-like enhancer protein 4.	Hairy/enhancer-of-split related with YRPW motif protein 1.	0.406
N309_00390	N309_14028	A0A099ZUT8	A0A099Z488	Transducin-like enhancer protein 4.	C-terminal-binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.573
N309_01082	N309_00390	A0A099ZB48	A0A099ZUT8	C-terminal-binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Transducin-like enhancer protein 4.	0.573
N309_01082	N309_01167	A0A099ZB48	A0A099ZW53	C-terminal-binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 3.	0.667
N309_01082	N309_01462	A0A099ZB48	A0A099ZB17	C-terminal-binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 1.	0.809
N309_01082	N309_02051	A0A099ZB48	A0A099YRK7	C-terminal-binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Transducin-like enhancer protein 3.	0.573