(29 nodes) Cytosolic DNA-sensing pathway network (Tinamus guttatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	N309_11771	DNA-directed RNA polymerase III subunit RPC2; Belongs to the RNA polymerase beta chain family. (803 aa)
	N309_04451	Caspase-1; Belongs to the peptidase C14A family. (384 aa)
	N309_01873	C-C motif chemokine. (91 aa)
	N309_14886	Proto-oncogene c-Rel. (587 aa)
	N309_15716	Double-stranded RNA-specific adenosine deaminase. (1066 aa)
	N309_07978	DNA-directed RNA polymerases I, II, and III subunit RPABC3. (126 aa)
	N309_12084	DNA-directed RNA polymerase III subunit RPC7. (215 aa)
	N309_10867	Interferon alpha-2. (184 aa)
	N309_14064	DNA-directed RNA polymerases I, II, and III subunit RPABC1. (183 aa)
	N309_10258	DNA-directed RNA polymerases I and III subunit RPAC1. (300 aa)
	N309_02250	DNA-directed RNA polymerase III subunit RPC8. (206 aa)
	N309_04791	DNA-directed RNA polymerases I, II, and III subunit RPABC2. (96 aa)
	N309_13796	DNA-directed RNA polymerases I and III subunit RPAC2. (86 aa)
	N309_05475	Serine/threonine-protein kinase TBK1. (716 aa)
	N309_15085	DNA-directed RNA polymerase III subunit RPC3. (54 aa)
	N309_12187	DNA-directed RNA polymerase III subunit RPC6. (299 aa)
	N309_05009	NF-kappa-B inhibitor alpha. (239 aa)
	N309_08225	DNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
	N309_09844	Interleukin-18. (194 aa)
	N309_07330	Stimulator of interferon genes protein. (375 aa)
	N309_01309	C-C motif chemokine. (65 aa)
	N309_15676	DNA-directed RNA polymerase III subunit RPC5. (702 aa)
	N309_12915	Nuclear factor NF-kappa-B p105 subunit. (880 aa)
	N309_05592	DNA-directed RNA polymerases I, II, and III subunit RPABC4. (55 aa)
	N309_14637	Inhibitor of nuclear factor kappa-B kinase subunit alpha. (670 aa)
	N309_01554	Inhibitor of nuclear factor kappa-B kinase subunit epsilon. (369 aa)
	N309_10832	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1375 aa)
	N309_03731	Inhibitor of nuclear factor kappa-B kinase subunit beta. (691 aa)
	N309_11199	Cyclic GMP-AMP synthase. (299 aa)

Your Current Organism:

Tinamus guttatus

NCBI taxonomy Id: 94827
Other names: T. guttatus, white-throated tinamou

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
N309_01309	N309_01873	A0A099ZH47	A0A099YTJ9	C-C motif chemokine.	C-C motif chemokine.	0.871
N309_01309	N309_05009	A0A099ZH47	A0A099ZK38	C-C motif chemokine.	NF-kappa-B inhibitor alpha.	0.820
N309_01309	N309_12915	A0A099ZH47	A0A099ZB38	C-C motif chemokine.	Nuclear factor NF-kappa-B p105 subunit.	0.848
N309_01309	N309_14886	A0A099ZH47	A0A099YU50	C-C motif chemokine.	Proto-oncogene c-Rel.	0.832
N309_01554	N309_03731	A0A099Z595	A0A099Z2S0	Inhibitor of nuclear factor kappa-B kinase subunit epsilon.	Inhibitor of nuclear factor kappa-B kinase subunit beta.	0.443
N309_01554	N309_05009	A0A099Z595	A0A099ZK38	Inhibitor of nuclear factor kappa-B kinase subunit epsilon.	NF-kappa-B inhibitor alpha.	0.761
N309_01554	N309_05475	A0A099Z595	A0A099ZKZ3	Inhibitor of nuclear factor kappa-B kinase subunit epsilon.	Serine/threonine-protein kinase TBK1.	0.817
N309_01554	N309_07330	A0A099Z595	A0A099ZHA4	Inhibitor of nuclear factor kappa-B kinase subunit epsilon.	Stimulator of interferon genes protein.	0.973
N309_01554	N309_12915	A0A099Z595	A0A099ZB38	Inhibitor of nuclear factor kappa-B kinase subunit epsilon.	Nuclear factor NF-kappa-B p105 subunit.	0.865
N309_01554	N309_14637	A0A099Z595	A0A099Z6A0	Inhibitor of nuclear factor kappa-B kinase subunit epsilon.	Inhibitor of nuclear factor kappa-B kinase subunit alpha.	0.480
N309_01554	N309_14886	A0A099Z595	A0A099YU50	Inhibitor of nuclear factor kappa-B kinase subunit epsilon.	Proto-oncogene c-Rel.	0.864
N309_01873	N309_01309	A0A099YTJ9	A0A099ZH47	C-C motif chemokine.	C-C motif chemokine.	0.871
N309_02250	N309_04791	A0A099ZNP6	A0A099ZMZ0	DNA-directed RNA polymerase III subunit RPC8.	DNA-directed RNA polymerases I, II, and III subunit RPABC2.	0.999
N309_02250	N309_05592	A0A099ZNP6	A0A099Z797	DNA-directed RNA polymerase III subunit RPC8.	DNA-directed RNA polymerases I, II, and III subunit RPABC4.	0.999
N309_02250	N309_07978	A0A099ZNP6	A0A099ZVB8	DNA-directed RNA polymerase III subunit RPC8.	DNA-directed RNA polymerases I, II, and III subunit RPABC3.	0.999
N309_02250	N309_08225	A0A099ZNP6	A0A099ZJF0	DNA-directed RNA polymerase III subunit RPC8.	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	0.999
N309_02250	N309_10258	A0A099ZNP6	A0A099ZRJ2	DNA-directed RNA polymerase III subunit RPC8.	DNA-directed RNA polymerases I and III subunit RPAC1.	0.999
N309_02250	N309_10832	A0A099ZNP6	A0A099Z476	DNA-directed RNA polymerase III subunit RPC8.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
N309_02250	N309_11771	A0A099ZNP6	A0A099Z131	DNA-directed RNA polymerase III subunit RPC8.	DNA-directed RNA polymerase III subunit RPC2; Belongs to the RNA polymerase beta chain family.	0.999
N309_02250	N309_12084	A0A099ZNP6	A0A099ZU22	DNA-directed RNA polymerase III subunit RPC8.	DNA-directed RNA polymerase III subunit RPC7.	0.998