(16 nodes) Mixed, incl. p21 activated kinase binding domain, and RasGAP C-terminus network (Callithrix jacchus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NCK1	Cytoplasmic protein. (377 aa)
	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor 6. (775 aa)
	IQGAP3	IQ motif containing GTPase activating protein 3. (1632 aa)
	PAK3	P21 (RAC1) activated kinase 3. (580 aa)
	NCK2	Cytoplasmic protein. (380 aa)
	TIAM1	T cell lymphoma invasion and metastasis 1. (1556 aa)
	GIT2	GIT ArfGAP 2. (759 aa)
	IQGAP1	IQ motif containing GTPase activating protein 1. (1657 aa)
	GIT1	ARF GTPase-activating protein GIT1 isoform 1. (770 aa)
	RAC3	Ras-related C3 botulinum toxin substrate 3. (192 aa)
	IQGAP2	IQ motif containing GTPase activating protein 2. (1575 aa)
	PAK5	Non-specific serine/threonine protein kinase. (719 aa)
	PAK1	Non-specific serine/threonine protein kinase. (554 aa)
	PAK2	Non-specific serine/threonine protein kinase. (524 aa)
	CDC42	Cell division control protein 42 homolog isoform 1. (191 aa)
	ARHGEF7	Uncharacterized protein. (862 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF6	ARHGEF7	ENSCJAP00000006648	ENSCJAP00000063810	Rac/Cdc42 guanine nucleotide exchange factor 6.	Uncharacterized protein.	0.968
ARHGEF6	CDC42	ENSCJAP00000006648	ENSCJAP00000063033	Rac/Cdc42 guanine nucleotide exchange factor 6.	Cell division control protein 42 homolog isoform 1.	0.716
ARHGEF6	GIT1	ENSCJAP00000006648	ENSCJAP00000025040	Rac/Cdc42 guanine nucleotide exchange factor 6.	ARF GTPase-activating protein GIT1 isoform 1.	0.992
ARHGEF6	GIT2	ENSCJAP00000006648	ENSCJAP00000017827	Rac/Cdc42 guanine nucleotide exchange factor 6.	GIT ArfGAP 2.	0.929
ARHGEF6	NCK1	ENSCJAP00000006648	ENSCJAP00000004536	Rac/Cdc42 guanine nucleotide exchange factor 6.	Cytoplasmic protein.	0.650
ARHGEF6	NCK2	ENSCJAP00000006648	ENSCJAP00000014923	Rac/Cdc42 guanine nucleotide exchange factor 6.	Cytoplasmic protein.	0.612
ARHGEF6	PAK1	ENSCJAP00000006648	ENSCJAP00000044445	Rac/Cdc42 guanine nucleotide exchange factor 6.	Non-specific serine/threonine protein kinase.	0.989
ARHGEF6	PAK2	ENSCJAP00000006648	ENSCJAP00000046282	Rac/Cdc42 guanine nucleotide exchange factor 6.	Non-specific serine/threonine protein kinase.	0.987
ARHGEF6	PAK3	ENSCJAP00000006648	ENSCJAP00000013437	Rac/Cdc42 guanine nucleotide exchange factor 6.	P21 (RAC1) activated kinase 3.	0.923
ARHGEF6	PAK5	ENSCJAP00000006648	ENSCJAP00000039733	Rac/Cdc42 guanine nucleotide exchange factor 6.	Non-specific serine/threonine protein kinase.	0.968
ARHGEF6	RAC3	ENSCJAP00000006648	ENSCJAP00000033666	Rac/Cdc42 guanine nucleotide exchange factor 6.	Ras-related C3 botulinum toxin substrate 3.	0.959
ARHGEF7	ARHGEF6	ENSCJAP00000063810	ENSCJAP00000006648	Uncharacterized protein.	Rac/Cdc42 guanine nucleotide exchange factor 6.	0.968
ARHGEF7	CDC42	ENSCJAP00000063810	ENSCJAP00000063033	Uncharacterized protein.	Cell division control protein 42 homolog isoform 1.	0.974
ARHGEF7	GIT1	ENSCJAP00000063810	ENSCJAP00000025040	Uncharacterized protein.	ARF GTPase-activating protein GIT1 isoform 1.	0.995
ARHGEF7	GIT2	ENSCJAP00000063810	ENSCJAP00000017827	Uncharacterized protein.	GIT ArfGAP 2.	0.941
ARHGEF7	NCK1	ENSCJAP00000063810	ENSCJAP00000004536	Uncharacterized protein.	Cytoplasmic protein.	0.575
ARHGEF7	NCK2	ENSCJAP00000063810	ENSCJAP00000014923	Uncharacterized protein.	Cytoplasmic protein.	0.715
ARHGEF7	PAK1	ENSCJAP00000063810	ENSCJAP00000044445	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.992
ARHGEF7	PAK2	ENSCJAP00000063810	ENSCJAP00000046282	Uncharacterized protein.	Non-specific serine/threonine protein kinase.	0.994
ARHGEF7	PAK3	ENSCJAP00000063810	ENSCJAP00000013437	Uncharacterized protein.	P21 (RAC1) activated kinase 3.	0.930