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| | MAP2K6 | Dual specificity mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (482 aa) |
| | PPM1D | Protein phosphatase, Mg2+/Mn2+ dependent 1D. (605 aa) |
| | MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa) |
| | FOSL1 | FOS like 1, AP-1 transcription factor subunit. (271 aa) |
| | MAP3K11 | Mitogen-activated protein kinase kinase kinase. (847 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1. (1508 aa) |
| | MAP2K5 | Dual specificity mitogen-activated protein kinase kinase 5 isoform A; Belongs to the protein kinase superfamily. (448 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa) |
| | PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1. (1710 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1335 aa) |
| | AKT1S1 | Proline-rich AKT1 substrate 1 isoform a. (276 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (647 aa) |
| | SGK3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa) |
| | CCNL1 | Cyclin-L1; Belongs to the cyclin family. (528 aa) |
| | ARFGEF1 | ADP ribosylation factor guanine nucleotide exchange factor 1. (1849 aa) |
| | DEPTOR | DEP domain-containing mTOR-interacting protein. (409 aa) |
| | FOXO3 | Forkhead box protein O3. (672 aa) |
| | DUSP10 | Dual specificity protein phosphatase 10 isoform a; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (482 aa) |
| | YWHAQ | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta; Belongs to the 14-3-3 family. (245 aa) |
| | MAPKAP1 | Target of rapamycin complex 2 subunit MAPKAP1 isoform 1. (522 aa) |
| | DDIT4 | DNA damage-inducible transcript 4 protein. (232 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1732 aa) |
| | F7I4B4_CALJA | Uncharacterized protein. (85 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1481 aa) |
| | TCHP | Trichoplein keratin filament-binding protein. (498 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (441 aa) |
| | CCNL2 | Uncharacterized protein; Belongs to the cyclin family. (518 aa) |
| | MAPK8IP1 | Mitogen-activated protein kinase 8 interacting protein 1. (713 aa) |
| | F6TG91_CALJA | Uncharacterized protein. (159 aa) |
| | ARAF | Serine/threonine-protein kinase A-Raf isoform 1. (611 aa) |
| | FOSB | FosB proto-oncogene, AP-1 transcription factor subunit. (338 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (450 aa) |
| | ZFP36 | ZFP36 ring finger protein. (332 aa) |
| | AKT2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa) |
| | PDPK1 | 3-phosphoinositide-dependent protein kinase 1 isoform 1. (556 aa) |
| | PHLPP2 | PPM-type phosphatase domain-containing protein. (1357 aa) |
| | MLST8 | Target of rapamycin complex subunit LST8 isoform a. (326 aa) |
| | MAP2K2 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (401 aa) |
| | TSC2 | TSC complex subunit 2. (1794 aa) |
| | LOC100386005 | C-type lectin domain-containing protein. (255 aa) |
| | YWHAZ | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (314 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (668 aa) |
| | MDM4 | Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | SGK2 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (427 aa) |
| | TSC1 | Hamartin isoform 3. (1168 aa) |
| | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3. (580 aa) |
| | ATF7 | Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (494 aa) |
| | NAV3 | Neuron navigator 3. (2385 aa) |
| | RHEB | Ras homolog, mTORC1 binding. (184 aa) |
| | KLF6 | Krueppel-like factor 6 isoform A. (283 aa) |
| | RHEBL1 | GTPase RhebL1. (183 aa) |
| | CDC25B | Cell division cycle 25B. (588 aa) |
| | DUSP16 | Dual specificity protein phosphatase 16. (661 aa) |
| | CDK14 | Cyclin-dependent kinase 14; Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuro [...] (469 aa) |
| | HIPK3 | Homeodomain-interacting protein kinase 3 isoform 1. (1216 aa) |
| | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (255 aa) |
| | KSR1 | Kinase suppressor of ras 1. (928 aa) |
| | PTPN7 | Protein tyrosine phosphatase non-receptor type 7. (497 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa) |
| | CHEK2 | Uncharacterized protein. (543 aa) |
| | SIRT1 | Sirtuin 1. (753 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa) |
| | F6TK20_CALJA | Mitogen-activated protein kinase kinase 7. (428 aa) |
| | PTPRR | Receptor-type tyrosine-protein phosphatase R isoform 1. (657 aa) |
| | MAPK15 | Mitogen-activated protein kinase. (624 aa) |
| | TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) |
| | FOSL2 | FOS like 2, AP-1 transcription factor subunit. (326 aa) |
| | ENSCJAP00000052888 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (134 aa) |
| | ATF3 | Cyclic AMP-dependent transcription factor ATF-3 isoform 1. (181 aa) |
| | YWHAG | 14-3-3 protein gamma; Belongs to the 14-3-3 family. (247 aa) |
| | YWHAH | Uncharacterized protein. (70 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | APPBP2 | Amyloid beta precursor protein binding protein 2. (585 aa) |
| | YWHAB | 14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (246 aa) |
| | TBC1D7 | TBC1 domain family member 7 isoform a. (293 aa) |
| | SETD7 | Histone-lysine N-methyltransferase SETD7; Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes. (366 aa) |
| | MAP2K4 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (410 aa) |
| | ENSCJAP00000057830 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (246 aa) |
| | CTNNA3 | Catenin alpha 3. (895 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (381 aa) |
| | TP73 | Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (635 aa) |
| | MAP2K3 | Dual specificity mitogen-activated protein kinase kinase 3 isoform B; Belongs to the protein kinase superfamily. (347 aa) |
| | ENSCJAP00000060543 | Uncharacterized protein. (520 aa) |
| | BRAF | Uncharacterized protein. (805 aa) |
| | FOXO6 | Forkhead box O6. (830 aa) |
| | MARK3 | Non-specific serine/threonine protein kinase. (753 aa) |
| | CTNNA2 | Catenin alpha 2. (953 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (552 aa) |
| | ENSCJAP00000065499 | Uncharacterized protein. (77 aa) |
| | SFN | Stratifin; Belongs to the 14-3-3 family. (248 aa) |
| | ENSCJAP00000066270 | Protein kinase domain-containing protein. (213 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (396 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | ENSCJAP00000068152 | Uncharacterized protein. (132 aa) |
| | ENSCJAP00000068553 | 14_3_3 domain-containing protein. (105 aa) |
| | FOXO1 | Fork-head domain-containing protein. (654 aa) |
| | FOXO4 | Forkhead box O4. (508 aa) |
| | LRRK2 | Leucine rich repeat kinase 2. (2506 aa) |
| | ENSCJAP00000070008 | Uncharacterized protein. (89 aa) |
| | PTPN5 | Protein tyrosine phosphatase non-receptor type 5. (779 aa) |
| | DUSP1 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (459 aa) |
| | ENSCJAP00000071129 | Fork-head domain-containing protein. (540 aa) |
| | ENSCJAP00000071975 | Uncharacterized protein. (341 aa) |
| | ENSCJAP00000072152 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (274 aa) |
| | MAPKAPK2 | MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (439 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (466 aa) |
| | MAPK8IP2 | Mitogen-activated protein kinase 8 interacting protein 2. (835 aa) |
| | FOS | Proto-oncogene c-Fos. (380 aa) |
| | ENSCJAP00000073428 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (343 aa) |
| | ENSCJAP00000073727 | Uncharacterized protein. (122 aa) |
| | ENSCJAP00000073818 | Uncharacterized protein. (106 aa) |
| | DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa) |
| | ENSCJAP00000074681 | 14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (227 aa) |
| | LSP1 | Uncharacterized protein. (731 aa) |
| | ENSCJAP00000074868 | Protein kinase domain-containing protein. (245 aa) |
| | CDKN2A | Uncharacterized protein. (273 aa) |
| | ENSCJAP00000075085 | Uncharacterized protein. (120 aa) |
| | JUND | JunD proto-oncogene, AP-1 transcription factor subunit. (318 aa) |
| | ENSCJAP00000076896 | Uncharacterized protein. (567 aa) |
| | ENSCJAP00000077446 | Uncharacterized protein. (317 aa) |
| | MAPKAPK3 | MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (442 aa) |
| | ENSCJAP00000078920 | Uncharacterized protein. (247 aa) |
| | DUSP8 | Dual specificity phosphatase 8. (621 aa) |
