STRINGSTRING
FZD4 FZD4 WNT5B WNT5B GPC3 GPC3 PRICKLE4 PRICKLE4 WNT2 WNT2 DVL1 DVL1 VANGL2 VANGL2 WNT8A WNT8A KLHL12 KLHL12 WNT5A WNT5A DKK4 DKK4 DAAM2 DAAM2 SFRP1 SFRP1 WNT6 WNT6 WNT10A WNT10A CER1 CER1 BAMBI BAMBI WIF1 WIF1 WNT11 WNT11 FZD3 FZD3 LRP5 LRP5 ROR1 ROR1 WNT3 WNT3 DVL2 DVL2 WNT7A WNT7A WLS WLS PRICKLE1 PRICKLE1 NOTUM NOTUM DAAM1 DAAM1 WNT9B WNT9B WNT10B WNT10B WNT1 WNT1 FZD5 FZD5 DACT1 DACT1 VANGL1 VANGL1 SFRP2 SFRP2 FZD6 FZD6 SFRP5 SFRP5 PORCN PORCN LRP6 LRP6 WNT8B WNT8B FZD7 FZD7 SFRP4 SFRP4 FZD9 FZD9 PRICKLE2 PRICKLE2 PRICKLE3 PRICKLE3 RYK RYK WNT2B WNT2B FZD2 FZD2 FZD1 FZD1 WNT4 WNT4 WNT9A WNT9A FZD10 FZD10 ENSCJAP00000070395 ENSCJAP00000070395 WNT3A WNT3A WNT7B WNT7B DKK2 DKK2 ENSCJAP00000075321 ENSCJAP00000075321 ENSCJAP00000075867 ENSCJAP00000075867 DKK1 DKK1 WNT16 WNT16 DVL3 DVL3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
PRICKLE4Prickle-like protein 4. (386 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
DVL1Dishevelled segment polarity protein 1. (695 aa)
VANGL2Vang-like protein. (521 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
KLHL12Kelch like family member 12. (638 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
DKK4Dickkopf WNT signaling pathway inhibitor 4. (224 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1126 aa)
SFRP1Secreted frizzled-related protein 1. (314 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
WIF1Wnt inhibitory factor 1. (379 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (476 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (681 aa)
LRP5Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1611 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2. (736 aa)
WNT7AProtein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (349 aa)
WLSProtein wntless homolog isoform 2. (545 aa)
PRICKLE1Prickle planar cell polarity protein 1. (831 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (504 aa)
DAAM1Disheveled-associated activator of morphogenesis 1 isoform 1. (1078 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (837 aa)
VANGL1Vang-like protein. (541 aa)
SFRP2Secreted frizzled related protein 2. (538 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
SFRP5Secreted frizzled related protein 5. (315 aa)
PORCNPorcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (525 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (620 aa)
SFRP4Secreted frizzled related protein 4. (346 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
PRICKLE2Prickle planar cell polarity protein 2. (900 aa)
PRICKLE3Prickle planar cell polarity protein 3. (611 aa)
RYKReceptor like tyrosine kinase. (629 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
FZD1Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (412 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
ENSCJAP00000070395GAIN domain-containing protein. (157 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
DKK2Dickkopf_N domain-containing protein. (259 aa)
ENSCJAP00000075321Ig-like domain-containing protein. (197 aa)
ENSCJAP00000075867Sclerostin. (213 aa)
DKK1Dickkopf_N domain-containing protein. (332 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
DVL3Dishevelled segment polarity protein 3. (750 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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