(15 nodes) Mixed, incl. Cell proliferation in midbrain, and Wnt signaling pathway, calcium modulating pathway network (Callithrix jacchus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	FZD4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
	WNT5B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
	WNT2	Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	SFRP1	Secreted frizzled-related protein 1. (314 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (476 aa)
	FZD3	Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (681 aa)
	WNT1	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
	FZD6	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
	SFRP5	Secreted frizzled related protein 5. (315 aa)
	RYK	Receptor like tyrosine kinase. (629 aa)
	FZD2	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
	WNT4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
	FZD10	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
	WNT16	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FZD10	FZD3	ENSCJAP00000068385	ENSCJAP00000028677	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family.	0.430
FZD10	FZD6	ENSCJAP00000068385	ENSCJAP00000047621	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.	0.456
FZD10	RYK	ENSCJAP00000068385	ENSCJAP00000061311	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor like tyrosine kinase.	0.923
FZD10	SFRP1	ENSCJAP00000068385	ENSCJAP00000020434	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 1.	0.679
FZD10	SFRP5	ENSCJAP00000068385	ENSCJAP00000051114	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled related protein 5.	0.679
FZD10	WNT1	ENSCJAP00000068385	ENSCJAP00000038741	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.970
FZD10	WNT11	ENSCJAP00000068385	ENSCJAP00000028198	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.968
FZD10	WNT16	ENSCJAP00000068385	ENSCJAP00000077657	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.873
FZD10	WNT2	ENSCJAP00000068385	ENSCJAP00000009098	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity).	0.839
FZD10	WNT4	ENSCJAP00000068385	ENSCJAP00000067759	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.883
FZD10	WNT5A	ENSCJAP00000068385	ENSCJAP00000014370	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.971
FZD10	WNT5B	ENSCJAP00000068385	ENSCJAP00000001170	Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.975
FZD2	FZD3	ENSCJAP00000066438	ENSCJAP00000028677	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family.	0.444
FZD2	FZD6	ENSCJAP00000066438	ENSCJAP00000047621	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.	0.450
FZD2	RYK	ENSCJAP00000066438	ENSCJAP00000061311	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.	Receptor like tyrosine kinase.	0.928
FZD2	SFRP1	ENSCJAP00000066438	ENSCJAP00000020434	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 1.	0.830
FZD2	SFRP5	ENSCJAP00000066438	ENSCJAP00000051114	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled related protein 5.	0.702
FZD2	WNT1	ENSCJAP00000066438	ENSCJAP00000038741	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.978
FZD2	WNT11	ENSCJAP00000066438	ENSCJAP00000028198	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.975
FZD2	WNT16	ENSCJAP00000066438	ENSCJAP00000077657	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.832