(12 nodes) Wnt, and Wnt protein secretion network (Callithrix jacchus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GPC3	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (580 aa)
	WNT8A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
	WNT6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
	WNT10A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
	WIF1	Wnt inhibitory factor 1. (379 aa)
	WNT3	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	WLS	Protein wntless homolog isoform 2. (545 aa)
	NOTUM	Notum, palmitoleoyl-protein carboxylesterase. (504 aa)
	PORCN	Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (525 aa)
	WNT2B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
	WNT9A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (412 aa)
	WNT3A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GPC3	NOTUM	ENSCJAP00000007662	ENSCJAP00000033755	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Notum, palmitoleoyl-protein carboxylesterase.	0.714
GPC3	WNT10A	ENSCJAP00000007662	ENSCJAP00000020974	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.911
GPC3	WNT2B	ENSCJAP00000007662	ENSCJAP00000062587	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.920
GPC3	WNT3	ENSCJAP00000007662	ENSCJAP00000030660	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.935
GPC3	WNT3A	ENSCJAP00000007662	ENSCJAP00000071797	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.956
GPC3	WNT6	ENSCJAP00000007662	ENSCJAP00000020947	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.918
GPC3	WNT8A	ENSCJAP00000007662	ENSCJAP00000011494	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.918
GPC3	WNT9A	ENSCJAP00000007662	ENSCJAP00000068212	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.913
NOTUM	GPC3	ENSCJAP00000033755	ENSCJAP00000007662	Notum, palmitoleoyl-protein carboxylesterase.	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.714
NOTUM	WIF1	ENSCJAP00000033755	ENSCJAP00000026960	Notum, palmitoleoyl-protein carboxylesterase.	Wnt inhibitory factor 1.	0.452
NOTUM	WNT10A	ENSCJAP00000033755	ENSCJAP00000020974	Notum, palmitoleoyl-protein carboxylesterase.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.919
NOTUM	WNT2B	ENSCJAP00000033755	ENSCJAP00000062587	Notum, palmitoleoyl-protein carboxylesterase.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.923
NOTUM	WNT3	ENSCJAP00000033755	ENSCJAP00000030660	Notum, palmitoleoyl-protein carboxylesterase.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.940
NOTUM	WNT3A	ENSCJAP00000033755	ENSCJAP00000071797	Notum, palmitoleoyl-protein carboxylesterase.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.922
NOTUM	WNT6	ENSCJAP00000033755	ENSCJAP00000020947	Notum, palmitoleoyl-protein carboxylesterase.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.926
NOTUM	WNT8A	ENSCJAP00000033755	ENSCJAP00000011494	Notum, palmitoleoyl-protein carboxylesterase.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.922
NOTUM	WNT9A	ENSCJAP00000033755	ENSCJAP00000068212	Notum, palmitoleoyl-protein carboxylesterase.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.927
PORCN	WLS	ENSCJAP00000052950	ENSCJAP00000032318	Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family.	Protein wntless homolog isoform 2.	0.665
PORCN	WNT10A	ENSCJAP00000052950	ENSCJAP00000020974	Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.948
PORCN	WNT2B	ENSCJAP00000052950	ENSCJAP00000062587	Porcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.953