STRINGSTRING
BMPR2 BMPR2 NBL1 NBL1 BMPR1B BMPR1B GDF7 GDF7 GDF11 GDF11 ACVR2B ACVR2B INHA INHA GDF2 GDF2 CHRD CHRD ACVR1 ACVR1 NODAL NODAL GDF5 GDF5 ACVRL1 ACVRL1 ACVR1B ACVR1B BMP10 BMP10 ENG ENG BMP6 BMP6 BMP8A BMP8A INHBE INHBE BMPR1A BMPR1A NOG NOG GREM2 GREM2 FST FST ACVR1C ACVR1C INHBB INHBB INHBA INHBA BMP4 BMP4 BMP7 BMP7 ACVR2A ACVR2A BMP5 BMP5 BMP2 BMP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
NBL1NBL1, DAN family BMP antagonist. (216 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GDF7Growth differentiation factor 7. (449 aa)
GDF11Growth differentiation factor 11. (408 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (370 aa)
GDF2Growth differentiation factor 2. (426 aa)
CHRDChordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (967 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
NODALNodal growth differentiation factor. (346 aa)
GDF5Growth differentiation factor 5. (501 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (517 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
ENGEndoglin. (655 aa)
BMP6Bone morphogenetic protein 6. (504 aa)
BMP8ABone morphogenetic protein 8B preproprotein. (402 aa)
INHBEInhibin subunit beta E. (350 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
GREM2Gremlin. (168 aa)
FSTFollistatin isoform FST344. (344 aa)
ACVR1CTGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (579 aa)
INHBBInhibin subunit beta B. (407 aa)
INHBAInhibin subunit beta A. (426 aa)
BMP4Bone morphogenetic protein 4 preproprotein. (408 aa)
BMP7Bone morphogenetic protein 7. (430 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
BMP5Bone morphogenetic protein 5. (472 aa)
BMP2Bone morphogenetic protein 2. (401 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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