(17 nodes) Mixed, incl. Response to amiloride, and E3 ubiquitin-protein ligase, SMURF1 type network (Callithrix jacchus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WWP1	E3 ubiquitin-protein ligase. (922 aa)
	SCNN1A	Sodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (726 aa)
	SGK1	Non-specific serine/threonine protein kinase. (725 aa)
	NUMB	NUMB endocytic adaptor protein. (651 aa)
	NUMBL	NUMB like endocytic adaptor protein. (595 aa)
	NDFIP1	Nedd4 family interacting protein 1. (242 aa)
	ITCH	E3 ubiquitin-protein ligase. (864 aa)
	SCNN1B	Sodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (683 aa)
	WWP2	E3 ubiquitin-protein ligase. (870 aa)
	DTX2	Putative E3 ubiquitin-protein ligase DTX2 isoform a. (620 aa)
	ARRDC3	Arrestin domain-containing protein 3. (414 aa)
	NEDD4L	NEDD4 like E3 ubiquitin protein ligase. (1254 aa)
	NEDD4	NEDD4 E3 ubiquitin protein ligase. (1319 aa)
	SCNN1G	Sodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (650 aa)
	ENSCJAP00000073251	HECT domain-containing protein. (58 aa)
	TPTE2	Uncharacterized protein. (505 aa)
	SCNN1D	Sodium channel epithelial 1 delta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (646 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARRDC3	ITCH	ENSCJAP00000062786	ENSCJAP00000033864	Arrestin domain-containing protein 3.	E3 ubiquitin-protein ligase.	0.489
ARRDC3	NEDD4	ENSCJAP00000062786	ENSCJAP00000066364	Arrestin domain-containing protein 3.	NEDD4 E3 ubiquitin protein ligase.	0.913
ARRDC3	NEDD4L	ENSCJAP00000062786	ENSCJAP00000066326	Arrestin domain-containing protein 3.	NEDD4 like E3 ubiquitin protein ligase.	0.676
ARRDC3	WWP2	ENSCJAP00000062786	ENSCJAP00000045321	Arrestin domain-containing protein 3.	E3 ubiquitin-protein ligase.	0.612
DTX2	ENSCJAP00000073251	ENSCJAP00000048050	ENSCJAP00000073251	Putative E3 ubiquitin-protein ligase DTX2 isoform a.	HECT domain-containing protein.	0.656
DTX2	ITCH	ENSCJAP00000048050	ENSCJAP00000033864	Putative E3 ubiquitin-protein ligase DTX2 isoform a.	E3 ubiquitin-protein ligase.	0.670
DTX2	NEDD4	ENSCJAP00000048050	ENSCJAP00000066364	Putative E3 ubiquitin-protein ligase DTX2 isoform a.	NEDD4 E3 ubiquitin protein ligase.	0.455
DTX2	NEDD4L	ENSCJAP00000048050	ENSCJAP00000066326	Putative E3 ubiquitin-protein ligase DTX2 isoform a.	NEDD4 like E3 ubiquitin protein ligase.	0.455
DTX2	WWP1	ENSCJAP00000048050	ENSCJAP00000000563	Putative E3 ubiquitin-protein ligase DTX2 isoform a.	E3 ubiquitin-protein ligase.	0.656
DTX2	WWP2	ENSCJAP00000048050	ENSCJAP00000045321	Putative E3 ubiquitin-protein ligase DTX2 isoform a.	E3 ubiquitin-protein ligase.	0.656
ENSCJAP00000073251	DTX2	ENSCJAP00000073251	ENSCJAP00000048050	HECT domain-containing protein.	Putative E3 ubiquitin-protein ligase DTX2 isoform a.	0.656
ENSCJAP00000073251	ITCH	ENSCJAP00000073251	ENSCJAP00000033864	HECT domain-containing protein.	E3 ubiquitin-protein ligase.	0.707
ENSCJAP00000073251	NDFIP1	ENSCJAP00000073251	ENSCJAP00000033846	HECT domain-containing protein.	Nedd4 family interacting protein 1.	0.558
ENSCJAP00000073251	NUMB	ENSCJAP00000073251	ENSCJAP00000026390	HECT domain-containing protein.	NUMB endocytic adaptor protein.	0.574
ENSCJAP00000073251	NUMBL	ENSCJAP00000073251	ENSCJAP00000027304	HECT domain-containing protein.	NUMB like endocytic adaptor protein.	0.574
ENSCJAP00000073251	SCNN1A	ENSCJAP00000073251	ENSCJAP00000001205	HECT domain-containing protein.	Sodium channel epithelial 1 alpha subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.408
ENSCJAP00000073251	SCNN1B	ENSCJAP00000073251	ENSCJAP00000038280	HECT domain-containing protein.	Sodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.444
ENSCJAP00000073251	SCNN1G	ENSCJAP00000073251	ENSCJAP00000072896	HECT domain-containing protein.	Sodium channel epithelial 1 gamma subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.	0.427
ENSCJAP00000073251	SGK1	ENSCJAP00000073251	ENSCJAP00000005050	HECT domain-containing protein.	Non-specific serine/threonine protein kinase.	0.463
ENSCJAP00000073251	TPTE2	ENSCJAP00000073251	ENSCJAP00000073397	HECT domain-containing protein.	Uncharacterized protein.	0.568