node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HGF | HGFAC | ENSCJAP00000006156 | ENSCJAP00000025782 | Hepatocyte growth factor; Belongs to the peptidase S1 family. | HGF activator. | 0.651 |
HGF | MET | ENSCJAP00000006156 | ENSCJAP00000009442 | Hepatocyte growth factor; Belongs to the peptidase S1 family. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.999 |
HGF | MST1R | ENSCJAP00000006156 | ENSCJAP00000008287 | Hepatocyte growth factor; Belongs to the peptidase S1 family. | Macrophage stimulating 1 receptor. | 0.903 |
HGF | PTPRJ | ENSCJAP00000006156 | ENSCJAP00000038282 | Hepatocyte growth factor; Belongs to the peptidase S1 family. | Protein tyrosine phosphatase receptor type J. | 0.668 |
HGFAC | HGF | ENSCJAP00000025782 | ENSCJAP00000006156 | HGF activator. | Hepatocyte growth factor; Belongs to the peptidase S1 family. | 0.651 |
HGFAC | MET | ENSCJAP00000025782 | ENSCJAP00000009442 | HGF activator. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.894 |
HGFAC | MST1 | ENSCJAP00000025782 | ENSCJAP00000007513 | HGF activator. | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. | 0.554 |
HGFAC | MST1R | ENSCJAP00000025782 | ENSCJAP00000008287 | HGF activator. | Macrophage stimulating 1 receptor. | 0.857 |
MET | HGF | ENSCJAP00000009442 | ENSCJAP00000006156 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Hepatocyte growth factor; Belongs to the peptidase S1 family. | 0.999 |
MET | HGFAC | ENSCJAP00000009442 | ENSCJAP00000025782 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | HGF activator. | 0.894 |
MET | MST1 | ENSCJAP00000009442 | ENSCJAP00000007513 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. | 0.855 |
MET | MST1R | ENSCJAP00000009442 | ENSCJAP00000008287 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Macrophage stimulating 1 receptor. | 0.740 |
MET | PTPRJ | ENSCJAP00000009442 | ENSCJAP00000038282 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Protein tyrosine phosphatase receptor type J. | 0.936 |
MST1 | HGFAC | ENSCJAP00000007513 | ENSCJAP00000025782 | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. | HGF activator. | 0.554 |
MST1 | MET | ENSCJAP00000007513 | ENSCJAP00000009442 | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.855 |
MST1 | MST1R | ENSCJAP00000007513 | ENSCJAP00000008287 | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. | Macrophage stimulating 1 receptor. | 0.981 |
MST1 | PTPRJ | ENSCJAP00000007513 | ENSCJAP00000038282 | Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. | Protein tyrosine phosphatase receptor type J. | 0.410 |
MST1R | HGF | ENSCJAP00000008287 | ENSCJAP00000006156 | Macrophage stimulating 1 receptor. | Hepatocyte growth factor; Belongs to the peptidase S1 family. | 0.903 |
MST1R | HGFAC | ENSCJAP00000008287 | ENSCJAP00000025782 | Macrophage stimulating 1 receptor. | HGF activator. | 0.857 |
MST1R | MET | ENSCJAP00000008287 | ENSCJAP00000009442 | Macrophage stimulating 1 receptor. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.740 |