(22 nodes) Mixed, incl. SAM / Pointed domain, and Core-binding factor complex network (Callithrix jacchus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RUNX1	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (480 aa)
	LHX2	LIM/homeobox protein Lhx2. (406 aa)
	MYB	MYB proto-oncogene, transcription factor. (761 aa)
	ETS2	Protein C-ets-2; Transcription factor; Belongs to the ETS family. (469 aa)
	ERG	Uncharacterized protein. (507 aa)
	ETS1	ETS proto-oncogene 1, transcription factor. (551 aa)
	FLI1	Uncharacterized protein. (453 aa)
	PAX5	Paired box 5. (393 aa)
	CDK10	Cyclin dependent kinase 10; Belongs to the protein kinase superfamily. (370 aa)
	GATA2	Endothelial transcription factor GATA-2 isoform 1. (480 aa)
	GATA3	GATA binding protein 3. (444 aa)
	RUNX3	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (430 aa)
	CBFB	Core-binding factor subunit beta isoform 1. (187 aa)
	LMO2	LIM domain only 2. (363 aa)
	GATA1	GATA binding protein 1. (413 aa)
	LDB1	LIM domain binding 1. (414 aa)
	TBX21	T-box transcription factor 21. (537 aa)
	ENSCJAP00000069099	Uncharacterized protein. (423 aa)
	TAL1	BHLH domain-containing protein. (406 aa)
	LDB2	LIM domain-binding protein 2 isoform a. (373 aa)
	LMO1	LIM domain only 1. (160 aa)
	ENSCJAP00000078049	Uncharacterized protein. (161 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBFB	ENSCJAP00000069099	ENSCJAP00000055772	ENSCJAP00000069099	Core-binding factor subunit beta isoform 1.	Uncharacterized protein.	0.408
CBFB	ENSCJAP00000078049	ENSCJAP00000055772	ENSCJAP00000078049	Core-binding factor subunit beta isoform 1.	Uncharacterized protein.	0.422
CBFB	ERG	ENSCJAP00000055772	ENSCJAP00000015085	Core-binding factor subunit beta isoform 1.	Uncharacterized protein.	0.602
CBFB	ETS1	ENSCJAP00000055772	ENSCJAP00000016543	Core-binding factor subunit beta isoform 1.	ETS proto-oncogene 1, transcription factor.	0.692
CBFB	ETS2	ENSCJAP00000055772	ENSCJAP00000014975	Core-binding factor subunit beta isoform 1.	Protein C-ets-2; Transcription factor; Belongs to the ETS family.	0.408
CBFB	FLI1	ENSCJAP00000055772	ENSCJAP00000016583	Core-binding factor subunit beta isoform 1.	Uncharacterized protein.	0.607
CBFB	GATA1	ENSCJAP00000055772	ENSCJAP00000060257	Core-binding factor subunit beta isoform 1.	GATA binding protein 1.	0.649
CBFB	GATA2	ENSCJAP00000055772	ENSCJAP00000038400	Core-binding factor subunit beta isoform 1.	Endothelial transcription factor GATA-2 isoform 1.	0.734
CBFB	GATA3	ENSCJAP00000055772	ENSCJAP00000053176	Core-binding factor subunit beta isoform 1.	GATA binding protein 3.	0.675
CBFB	LDB1	ENSCJAP00000055772	ENSCJAP00000064143	Core-binding factor subunit beta isoform 1.	LIM domain binding 1.	0.682
CBFB	LDB2	ENSCJAP00000055772	ENSCJAP00000070339	Core-binding factor subunit beta isoform 1.	LIM domain-binding protein 2 isoform a.	0.666
CBFB	LMO1	ENSCJAP00000055772	ENSCJAP00000073480	Core-binding factor subunit beta isoform 1.	LIM domain only 1.	0.572
CBFB	LMO2	ENSCJAP00000055772	ENSCJAP00000059468	Core-binding factor subunit beta isoform 1.	LIM domain only 2.	0.726
CBFB	PAX5	ENSCJAP00000055772	ENSCJAP00000019262	Core-binding factor subunit beta isoform 1.	Paired box 5.	0.561
CBFB	RUNX1	ENSCJAP00000055772	ENSCJAP00000005127	Core-binding factor subunit beta isoform 1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.989
CBFB	RUNX3	ENSCJAP00000055772	ENSCJAP00000053772	Core-binding factor subunit beta isoform 1.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.965
CBFB	TAL1	ENSCJAP00000055772	ENSCJAP00000069403	Core-binding factor subunit beta isoform 1.	BHLH domain-containing protein.	0.743
CDK10	ENSCJAP00000069099	ENSCJAP00000019835	ENSCJAP00000069099	Cyclin dependent kinase 10; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.536
CDK10	ETS2	ENSCJAP00000019835	ENSCJAP00000014975	Cyclin dependent kinase 10; Belongs to the protein kinase superfamily.	Protein C-ets-2; Transcription factor; Belongs to the ETS family.	0.536
ENSCJAP00000069099	CBFB	ENSCJAP00000069099	ENSCJAP00000055772	Uncharacterized protein.	Core-binding factor subunit beta isoform 1.	0.408