STRINGSTRING
FAM9B FAM9B SYCP3 SYCP3 DDX4 DDX4 DAZL DAZL BOLL BOLL NANOS3 NANOS3 PUM2 PUM2 NOBOX NOBOX SOHLH1 SOHLH1 ZBTB16 ZBTB16 STRA8 STRA8 AMH AMH GDF9 GDF9 SAMD4B SAMD4B DND1 DND1 ACR ACR AMHR2 AMHR2 FIGLA FIGLA LHX8 LHX8 NR5A1 NR5A1 NANOS2 NANOS2 FOXL2 FOXL2 BMP15 BMP15 NR0B1 NR0B1 NANOS1 NANOS1 SOX9 SOX9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FAM9BFamily with sequence similarity 9 member B. (235 aa)
SYCP3Cor1 domain-containing protein. (236 aa)
DDX4DEAD-box helicase 4; Belongs to the DEAD box helicase family. (724 aa)
DAZLDeleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts (By similarity). (316 aa)
BOLLBoule homolog, RNA binding protein. (295 aa)
NANOS3Nanos C2HC-type zinc finger 3; Belongs to the nanos family. (167 aa)
PUM2Pumilio homolog 2. (1066 aa)
NOBOXNOBOX oogenesis homeobox. (657 aa)
SOHLH1Spermatogenesis and oogenesis specific basic helix-loop-helix 1. (404 aa)
ZBTB16Zinc finger and BTB domain-containing protein 16. (673 aa)
STRA8Stimulated by retinoic acid 8. (330 aa)
AMHAnti-Mullerian hormone. (559 aa)
GDF9Growth differentiation factor 9. (455 aa)
SAMD4BSterile alpha motif domain containing 4B. (746 aa)
DND1DND microRNA-mediated repression inhibitor 1. (353 aa)
ACRAcrosin; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome. (402 aa)
AMHR2Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (568 aa)
FIGLAFolliculogenesis specific bHLH transcription factor. (219 aa)
LHX8LIM homeobox 8. (419 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
NANOS2Nanos C2HC-type zinc finger 2; Belongs to the nanos family. (141 aa)
FOXL2Forkhead box L2. (376 aa)
BMP15Bone morphogenetic protein 15. (392 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1; Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity). Belongs to the nuclear hormone receptor family. NR0 subfamily. (470 aa)
NANOS1Nanos C2HC-type zinc finger 1; Belongs to the nanos family. (413 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
Server load: low (18%) [HD]