(23 nodes) Catecholamine metabolic process, and Synuclein network (Callithrix jacchus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	OTOP1	Otopetrin 1. (612 aa)
	HDC	Histidine decarboxylase. (662 aa)
	SNCB	Beta-synuclein; Belongs to the synuclein family. (134 aa)
	INMT	Uncharacterized protein. (287 aa)
	PNMT	Phenylethanolamine N-methyltransferase. (275 aa)
	F7EDZ9_CALJA	Stathmin; Belongs to the stathmin family. (149 aa)
	DBH	Dopamine beta-hydroxylase. (621 aa)
	DRD4	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (392 aa)
	LRTOMT	Uncharacterized protein. (258 aa)
	AOC1	Amine oxidase. (755 aa)
	DRD5	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (476 aa)
	DRD3	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
	MAOB	Amine oxidase. (520 aa)
	COMT	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (233 aa)
	MAOA	Amine oxidase. (930 aa)
	DDC	Dopa decarboxylase. (480 aa)
	HNMT	Histamine N-methyltransferase isoform 1. (292 aa)
	TH	Tyrosine hydroxylase. (623 aa)
	SLC6A3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (587 aa)
	NCS1	Uncharacterized protein. (392 aa)
	SNCA	Uncharacterized protein. (197 aa)
	SNCAIP	Synuclein alpha interacting protein. (1015 aa)
	SNCG	Gamma-synuclein; Belongs to the synuclein family. (201 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOC1	DDC	ENSCJAP00000037447	ENSCJAP00000056273	Amine oxidase.	Dopa decarboxylase.	0.943
AOC1	HDC	ENSCJAP00000037447	ENSCJAP00000002677	Amine oxidase.	Histidine decarboxylase.	0.955
AOC1	HNMT	ENSCJAP00000037447	ENSCJAP00000065187	Amine oxidase.	Histamine N-methyltransferase isoform 1.	0.980
AOC1	INMT	ENSCJAP00000037447	ENSCJAP00000016136	Amine oxidase.	Uncharacterized protein.	0.911
AOC1	MAOA	ENSCJAP00000037447	ENSCJAP00000053476	Amine oxidase.	Amine oxidase.	0.938
AOC1	MAOB	ENSCJAP00000037447	ENSCJAP00000043756	Amine oxidase.	Amine oxidase.	0.953
COMT	DBH	ENSCJAP00000050671	ENSCJAP00000018396	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Dopamine beta-hydroxylase.	0.681
COMT	DDC	ENSCJAP00000050671	ENSCJAP00000056273	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Dopa decarboxylase.	0.967
COMT	DRD3	ENSCJAP00000050671	ENSCJAP00000043693	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family.	0.724
COMT	DRD4	ENSCJAP00000050671	ENSCJAP00000022145	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	0.923
COMT	DRD5	ENSCJAP00000050671	ENSCJAP00000042994	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family.	0.438
COMT	LRTOMT	ENSCJAP00000050671	ENSCJAP00000028099	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Uncharacterized protein.	0.913
COMT	MAOA	ENSCJAP00000050671	ENSCJAP00000053476	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Amine oxidase.	0.994
COMT	MAOB	ENSCJAP00000050671	ENSCJAP00000043756	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Amine oxidase.	0.993
COMT	PNMT	ENSCJAP00000050671	ENSCJAP00000016192	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Phenylethanolamine N-methyltransferase.	0.952
COMT	SLC6A3	ENSCJAP00000050671	ENSCJAP00000073040	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.756
COMT	TH	ENSCJAP00000050671	ENSCJAP00000068563	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	Tyrosine hydroxylase.	0.824
DBH	COMT	ENSCJAP00000018396	ENSCJAP00000050671	Dopamine beta-hydroxylase.	Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.	0.681
DBH	DDC	ENSCJAP00000018396	ENSCJAP00000056273	Dopamine beta-hydroxylase.	Dopa decarboxylase.	0.599
DBH	DRD4	ENSCJAP00000018396	ENSCJAP00000022145	Dopamine beta-hydroxylase.	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family.	0.544