(6 nodes) ATF6-mediated unfolded protein response network (Callithrix jacchus)

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Your Input:
	ATF4	Activating transcription factor 4. (351 aa)
	ATF6	Activating transcription factor 6. (669 aa)
	XBP1	BZIP domain-containing protein. (371 aa)
	DDIT3	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
	ATF6B	Cyclic AMP-dependent transcription factor ATF-6 beta isoform a. (700 aa)
	ENSCJAP00000059748	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (195 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF4	ATF6	ENSCJAP00000004703	ENSCJAP00000008327	Activating transcription factor 4.	Activating transcription factor 6.	0.879
ATF4	ATF6B	ENSCJAP00000004703	ENSCJAP00000052186	Activating transcription factor 4.	Cyclic AMP-dependent transcription factor ATF-6 beta isoform a.	0.949
ATF4	DDIT3	ENSCJAP00000004703	ENSCJAP00000043609	Activating transcription factor 4.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.991
ATF4	ENSCJAP00000059748	ENSCJAP00000004703	ENSCJAP00000059748	Activating transcription factor 4.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.991
ATF4	XBP1	ENSCJAP00000004703	ENSCJAP00000037339	Activating transcription factor 4.	BZIP domain-containing protein.	0.890
ATF6	ATF4	ENSCJAP00000008327	ENSCJAP00000004703	Activating transcription factor 6.	Activating transcription factor 4.	0.879
ATF6	ATF6B	ENSCJAP00000008327	ENSCJAP00000052186	Activating transcription factor 6.	Cyclic AMP-dependent transcription factor ATF-6 beta isoform a.	0.916
ATF6	DDIT3	ENSCJAP00000008327	ENSCJAP00000043609	Activating transcription factor 6.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.986
ATF6	ENSCJAP00000059748	ENSCJAP00000008327	ENSCJAP00000059748	Activating transcription factor 6.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.986
ATF6	XBP1	ENSCJAP00000008327	ENSCJAP00000037339	Activating transcription factor 6.	BZIP domain-containing protein.	0.964
ATF6B	ATF4	ENSCJAP00000052186	ENSCJAP00000004703	Cyclic AMP-dependent transcription factor ATF-6 beta isoform a.	Activating transcription factor 4.	0.949
ATF6B	ATF6	ENSCJAP00000052186	ENSCJAP00000008327	Cyclic AMP-dependent transcription factor ATF-6 beta isoform a.	Activating transcription factor 6.	0.916
ATF6B	DDIT3	ENSCJAP00000052186	ENSCJAP00000043609	Cyclic AMP-dependent transcription factor ATF-6 beta isoform a.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.935
ATF6B	ENSCJAP00000059748	ENSCJAP00000052186	ENSCJAP00000059748	Cyclic AMP-dependent transcription factor ATF-6 beta isoform a.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.935
ATF6B	XBP1	ENSCJAP00000052186	ENSCJAP00000037339	Cyclic AMP-dependent transcription factor ATF-6 beta isoform a.	BZIP domain-containing protein.	0.712
DDIT3	ATF4	ENSCJAP00000043609	ENSCJAP00000004703	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	Activating transcription factor 4.	0.991
DDIT3	ATF6	ENSCJAP00000043609	ENSCJAP00000008327	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	Activating transcription factor 6.	0.986
DDIT3	ATF6B	ENSCJAP00000043609	ENSCJAP00000052186	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	Cyclic AMP-dependent transcription factor ATF-6 beta isoform a.	0.935
DDIT3	ENSCJAP00000059748	ENSCJAP00000043609	ENSCJAP00000059748	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.900
DDIT3	XBP1	ENSCJAP00000043609	ENSCJAP00000037339	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	BZIP domain-containing protein.	0.982