STRINGSTRING
SETD2 SETD2 MACROH2A1 MACROH2A1 LOC100415684 LOC100415684 LOC100385831 LOC100385831 KDM6B KDM6B LOC100396380 LOC100396380 H2AC20 H2AC20 LOC100394455 LOC100394455 LOC100388427 LOC100388427 LOC100394573 LOC100394573 LOC100413207 LOC100413207 H2BC21 H2BC21 H2AC21 H2AC21 H2BU1 H2BU1 LOC100388427-2 LOC100388427-2 LOC100396380-2 LOC100396380-2 H2AC6 H2AC6 ENSCJAP00000063804 ENSCJAP00000063804 LOC100385283 LOC100385283 LOC100415326 LOC100415326 H2BC3 H2BC3 ENSCJAP00000065541 ENSCJAP00000065541 ENSCJAP00000065716 ENSCJAP00000065716 HDAC5 HDAC5 H2BE1 H2BE1 LOC100390706 LOC100390706 LOC100388427-5 LOC100388427-5 LOC100388427-7 LOC100388427-7 LOC100388427-9 LOC100388427-9 LOC100386265 LOC100386265 LOC100388427-10 LOC100388427-10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SETD2SET domain containing 2, histone lysine methyltransferase. (2561 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
LOC100415684Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100385831Histone H3; Belongs to the histone H3 family. (135 aa)
KDM6BLysine-specific demethylase 6B. (1675 aa)
LOC100396380Histone H2A; Belongs to the histone H2A family. (130 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
LOC100394455Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100388427Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC100394573Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100413207Histone H3; Belongs to the histone H3 family. (135 aa)
H2BC21Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC21Histone H2A; Belongs to the histone H2A family. (130 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100388427-2Histone H4. (103 aa)
LOC100396380-2Histone H2A type 1. (130 aa)
H2AC6Histone H2A; Belongs to the histone H2A family. (130 aa)
ENSCJAP00000063804Histone H3; Belongs to the histone H3 family. (135 aa)
LOC100385283Histone H3; Belongs to the histone H3 family. (136 aa)
LOC100415326Histone H2B; Belongs to the histone H2B family. (126 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSCJAP00000065541Histone H3; Belongs to the histone H3 family. (136 aa)
ENSCJAP00000065716Histone H2B; Belongs to the histone H2B family. (126 aa)
HDAC5Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1124 aa)
H2BE1Histone H2B; Belongs to the histone H2B family. (122 aa)
LOC100390706Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC100388427-5Histone H4. (103 aa)
LOC100388427-7Histone H4. (103 aa)
LOC100388427-9Histone H4. (103 aa)
LOC100386265Histone domain-containing protein. (136 aa)
LOC100388427-10Histone H4. (103 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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