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F7HDR0_CALJA | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (453 aa) | ||||
TRIM28 | Tripartite motif containing 28. (835 aa) | ||||
RAD52 | RAD52 homolog, DNA repair protein. (419 aa) | ||||
F7HX86_CALJA | RAD51_interact domain-containing protein. (321 aa) | ||||
RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (569 aa) | ||||
YEATS4 | YEATS domain-containing protein 4. (227 aa) | ||||
ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) | ||||
NSD2 | Histone-lysine N-methyltransferase NSD2 isoform 1. (1365 aa) | ||||
MEAF6 | Chromatin modification-related protein MEAF6 isoform 1. (201 aa) | ||||
DPF2 | Uncharacterized protein. (430 aa) | ||||
SETD2 | SET domain containing 2, histone lysine methyltransferase. (2561 aa) | ||||
WAS | WASP actin nucleation promoting factor. (502 aa) | ||||
SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1105 aa) | ||||
RIF1 | Replication timing regulatory factor 1. (2463 aa) | ||||
KAT2B | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (832 aa) | ||||
EP400 | E1A binding protein p400. (3112 aa) | ||||
DMAP1 | DNA methyltransferase 1 associated protein 1. (569 aa) | ||||
FANCB | FA complementation group B. (863 aa) | ||||
PNKP | Polynucleotide kinase 3'-phosphatase. (521 aa) | ||||
DHX9 | DExH-box helicase 9. (1286 aa) | ||||
SPIRE1 | Protein spire homolog 1 isoform a. (757 aa) | ||||
DDX11 | DEAD/H-box helicase 11. (896 aa) | ||||
HELQ | Helicase, POLQ like. (1101 aa) | ||||
ABRAXAS1 | Abraxas 1, BRCA1 A complex subunit. (339 aa) | ||||
RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) | ||||
RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (486 aa) | ||||
TAF2 | TATA-box binding protein associated factor 2. (1323 aa) | ||||
KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (876 aa) | ||||
INO80D | INO80 complex subunit D. (1027 aa) | ||||
PARP3 | Poly [ADP-ribose] polymerase. (563 aa) | ||||
POLH | DNA polymerase eta. (709 aa) | ||||
SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1669 aa) | ||||
BRD8 | Uncharacterized protein. (1235 aa) | ||||
ENY2 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa) | ||||
F7HE85_CALJA | HMG box domain-containing protein. (411 aa) | ||||
PBRM1 | Polybromo 1. (1725 aa) | ||||
PPP4C | Serine/threonine-protein phosphatase. (307 aa) | ||||
CUL4A | Cullin 4A; Belongs to the cullin family. (763 aa) | ||||
DEK | DEK proto-oncogene. (381 aa) | ||||
INO80E | INO80 complex subunit E. (244 aa) | ||||
KAT7 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa) | ||||
UIMC1 | Ubiquitin interaction motif containing 1. (719 aa) | ||||
VPS72 | Vacuolar protein sorting 72 homolog. (375 aa) | ||||
ACTR8 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (630 aa) | ||||
UBQLN4 | Ubiquilin-4. (601 aa) | ||||
DTX3L | Deltex E3 ubiquitin ligase 3L. (745 aa) | ||||
PARP9 | Poly(ADP-ribose) polymerase family member 9. (835 aa) | ||||
FAM178B | Family with sequence similarity 178 member B. (678 aa) | ||||
RADX | RPA1 related single stranded DNA binding protein, X-linked. (855 aa) | ||||
POLQ | DNA polymerase theta. (2482 aa) | ||||
UCHL5 | Ubiquitin carboxyl-terminal hydrolase. (454 aa) | ||||
BABAM2 | BRISC and BRCA1 A complex member 2. (414 aa) | ||||
AUNIP | Aurora kinase A and ninein interacting protein. (369 aa) | ||||
EYA3 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (574 aa) | ||||
BABAM1 | BRISC and BRCA1-A complex member 1; Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'- linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. Component of the BRISC complex, a multiprotein complex that specifically cl [...] (329 aa) | ||||
WDR48 | WD repeat domain 48. (689 aa) | ||||
ARID1A | AT-rich interaction domain 1A. (2288 aa) | ||||
KHDC3L | KHDC3-like protein. (228 aa) | ||||
OOEP | Oocyte expressed protein homolog (Predicted). (149 aa) | ||||
CGAS | Cyclic GMP-AMP synthase. (547 aa) | ||||
MRNIP | MRN complex interacting protein. (335 aa) | ||||
ATXN7L3 | Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...] (354 aa) | ||||
SLF1 | Ankyrin repeat domain-containing protein 32. (1059 aa) | ||||
SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1590 aa) | ||||
SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (409 aa) | ||||
TIMELESS | Timeless circadian regulator. (1212 aa) | ||||
BARD1 | BRCA1 associated RING domain 1. (853 aa) | ||||
SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1245 aa) | ||||
SHLD2 | Shieldin complex subunit 2. (932 aa) | ||||
SUPT3H | SPT3 homolog, SAGA and STAGA complex component. (328 aa) | ||||
F7I8E1_CALJA | Uncharacterized protein. (66 aa) | ||||
EPC2 | Enhancer of polycomb homolog. (807 aa) | ||||
BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1830 aa) | ||||
ACTL6A | Actin-like protein 6A isoform 1; Belongs to the actin family. (429 aa) | ||||
ARID2 | AT-rich interaction domain 2. (1836 aa) | ||||
TRIP12 | Uncharacterized protein. (2040 aa) | ||||
MAD2L2 | Mitotic spindle assembly checkpoint protein MAD2B. (211 aa) | ||||
MFSD11 | Major facilitator superfamily domain containing 11. (454 aa) | ||||
ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1490 aa) | ||||
DPF1 | Zinc finger protein neuro-d4 isoform a. (424 aa) | ||||
EPC1 | Enhancer of polycomb homolog. (836 aa) | ||||
SPIDR | DUF4503 domain-containing protein. (397 aa) | ||||
TAF10 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (217 aa) | ||||
TERF2IP | Telomeric repeat-binding factor 2-interacting protein 1. (399 aa) | ||||
RECQL5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (990 aa) | ||||
MGMT | Methylated-DNA--protein-cysteine methyltransferase. (238 aa) | ||||
HELB | DNA helicase B. (1076 aa) | ||||
KAT2A | Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa) | ||||
WRAP53 | WD repeat containing antisense to TP53. (549 aa) | ||||
PIAS4 | Protein inhibitor of activated STAT 4. (509 aa) | ||||
SIRT6 | NAD-dependent protein deacetylase sirtuin-6 isoform 1. (355 aa) | ||||
ACTL6B | Actin-like protein 6B; Belongs to the actin family. (426 aa) | ||||
TERF2 | Telomeric repeat-binding factor; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat. (535 aa) | ||||
ZCWPW1 | Zinc finger CW-type and PWWP domain containing 1. (647 aa) | ||||
ERCC8 | ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (401 aa) | ||||
RPS3 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (282 aa) | ||||
SETMAR | SET domain and mariner transposase fusion gene. (684 aa) | ||||
RNF169 | Ring finger protein 169. (710 aa) | ||||
KMT5B | Histone-lysine N-methyltransferase SUV420H1 isoform 1. (883 aa) | ||||
RMI2 | Uncharacterized protein. (84 aa) | ||||
UBR5 | Ubiquitin protein ligase E3 component n-recognin 5. (2801 aa) | ||||
TRRAP | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3859 aa) | ||||
OGG1 | 8-oxoguanine DNA glycosylase. (423 aa) | ||||
RAD51AP1 | Uncharacterized protein. (219 aa) | ||||
BCL7B | B-cell CLL/lymphoma 7 protein family member B isoform 1. (202 aa) | ||||
EYA2 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (590 aa) | ||||
ING3 | Inhibitor of growth protein. (418 aa) | ||||
FH | Fumarate hydratase, mitochondrial. (510 aa) | ||||
AXIN2 | Axin-2. (842 aa) | ||||
HDGFL2 | Hepatoma-derived growth factor-related protein 2 isoform 1. (672 aa) | ||||
POT1 | Protection of telomeres 1. (617 aa) | ||||
PML | Promyelocytic leukemia. (881 aa) | ||||
TAF5 | Transcription initiation factor TFIID subunit 5. (800 aa) | ||||
SIRT7 | NAD-dependent protein deacetylase sirtuin-7. (400 aa) | ||||
OTUB1 | Ubiquitin thioesterase. (280 aa) | ||||
MBTD1 | MBT domain-containing protein 1. (630 aa) | ||||
TFPT | TCF3 fusion partner. (254 aa) | ||||
FOXM1 | Forkhead box M1. (763 aa) | ||||
SMARCD2 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2. (531 aa) | ||||
SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (600 aa) | ||||
ATXN7 | SCA7 domain-containing protein. (944 aa) | ||||
WRNIP1 | WRN helicase interacting protein 1. (666 aa) | ||||
TMEM161A | Transmembrane protein 161A isoform 1. (479 aa) | ||||
F6REP8_CALJA | Uncharacterized protein. (264 aa) | ||||
CDK9 | Cyclin dependent kinase 9; Belongs to the protein kinase superfamily. (487 aa) | ||||
CCDC117 | Coiled-coil domain-containing protein 117. (278 aa) | ||||
FBH1 | F-box only protein 18 isoform 2. (1045 aa) | ||||
INO80 | INO80 complex ATPase subunit. (1556 aa) | ||||
RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa) | ||||
MCRS1 | Microspherule protein 1. (475 aa) | ||||
SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa) | ||||
NPAS2 | Neuronal PAS domain-containing protein 2. (824 aa) | ||||
ENSCJAP00000039892 | Heat shock transcription factor 1. (557 aa) | ||||
RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (462 aa) | ||||
USP51 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (711 aa) | ||||
F6RGJ8_CALJA | Uncharacterized protein. (229 aa) | ||||
KMT5C | Lysine methyltransferase 5C. (463 aa) | ||||
USP1 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (783 aa) | ||||
TP53BP1 | Tumor protein p53 binding protein 1. (1971 aa) | ||||
SMARCE1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1. (411 aa) | ||||
TAF6 | TATA-box binding protein associated factor 6. (713 aa) | ||||
EYA4 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (645 aa) | ||||
SIRT1 | Sirtuin 1. (753 aa) | ||||
EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (643 aa) | ||||
CEBPG | CCAAT enhancer binding protein gamma. (150 aa) | ||||
CCDC197 | Coiled-coil domain containing 197. (270 aa) | ||||
PRKCG | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (698 aa) | ||||
POGZ | Pogo transposable element with ZNF domain isoform 1. (1410 aa) | ||||
ENY2-2 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa) | ||||
FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa) | ||||
NFRKB | Nuclear factor related to kappaB binding protein. (1311 aa) | ||||
TAF6L | TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L. (622 aa) | ||||
ZNF365 | Zinc finger protein 365. (436 aa) | ||||
TAF5L | TATA-box binding protein associated factor 5 like. (589 aa) | ||||
PHF10 | PHD finger protein 10. (562 aa) | ||||
TIGAR | TP53 induced glycolysis regulatory phosphatase. (270 aa) | ||||
TAF12 | Transcription initiation factor TFIID subunit 12. (161 aa) | ||||
ENY2-3 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa) | ||||
LOC100385843 | Uncharacterized protein. (147 aa) | ||||
MRGBP | MRG domain binding protein. (204 aa) | ||||
NUDT16L1 | Protein syndesmos isoform 1. (211 aa) | ||||
SPIRE2 | KIND domain-containing protein. (109 aa) | ||||
ENSCJAP00000058536 | Uncharacterized protein. (331 aa) | ||||
TEX15 | Testis expressed 15, meiosis and synapsis associated. (3169 aa) | ||||
PPP4R2 | Protein phosphatase 4 regulatory subunit 2. (432 aa) | ||||
UBE2V2 | Ubiquitin conjugating enzyme E2 V2. (186 aa) | ||||
C5H20orf196 | Uncharacterized protein. (62 aa) | ||||
SLF2 | Protein FAM178A isoform 1. (1171 aa) | ||||
ENSCJAP00000060587 | WD_REPEATS_REGION domain-containing protein. (307 aa) | ||||
RTEL1 | Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1309 aa) | ||||
USP22 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (525 aa) | ||||
RBBP8 | RB binding protein 8, endonuclease. (872 aa) | ||||
IER3 | Radiation-inducible immediate-early gene IEX-1. (156 aa) | ||||
ENSCJAP00000063462 | RECA_2 domain-containing protein. (204 aa) | ||||
ACTR2 | Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa) | ||||
DPF3 | Double PHD fingers 3. (412 aa) | ||||
OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2. (234 aa) | ||||
ENSCJAP00000064549 | Uncharacterized protein. (118 aa) | ||||
ENSCJAP00000064692 | HORMA domain-containing protein. (211 aa) | ||||
BCL7A | B-cell CLL/lymphoma 7 protein family member A isoform a. (231 aa) | ||||
ENSCJAP00000065525 | SWIB domain-containing protein. (481 aa) | ||||
SF3B5 | Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa) | ||||
ENY2-4 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (101 aa) | ||||
SUPT7L | SPT7 like, STAGA complex gamma subunit. (414 aa) | ||||
PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) | ||||
ENSCJAP00000067786 | Uncharacterized protein. (109 aa) | ||||
ENSCJAP00000067926 | HELICc2 domain-containing protein. (128 aa) | ||||
ENSCJAP00000067987 | Uncharacterized protein. (74 aa) | ||||
ENSCJAP00000068008 | Uncharacterized protein. (129 aa) | ||||
FAM168A | Family with sequence similarity 168 member A. (303 aa) | ||||
ENSCJAP00000068123 | SGF29 C-terminal domain-containing protein. (234 aa) | ||||
ENSCJAP00000068219 | SMC hinge domain-containing protein. (465 aa) | ||||
ENY2-5 | Transcription and mRNA export factor ENY2; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for trans [...] (90 aa) | ||||
ENSCJAP00000068469 | Uncharacterized protein. (113 aa) | ||||
ENSCJAP00000068891 | Uncharacterized protein. (94 aa) | ||||
ENSCJAP00000069100 | Uncharacterized protein. (104 aa) | ||||
SGF29 | SGF29 C-terminal domain-containing protein. (428 aa) | ||||
SMCHD1 | SMC hinge domain-containing protein. (2007 aa) | ||||
ENSCJAP00000069435 | HMG box domain-containing protein. (110 aa) | ||||
ENSCJAP00000069511 | DUF1725 domain-containing protein. (142 aa) | ||||
ENSCJAP00000070453 | Uncharacterized protein. (466 aa) | ||||
ENSCJAP00000070597 | Uncharacterized protein. (87 aa) | ||||
MMS19 | MMS19 homolog, cytosolic iron-sulfur assembly component. (1040 aa) | ||||
KLHL15 | Kelch-like protein 15. (604 aa) | ||||
PARP1 | Poly [ADP-ribose] polymerase. (1040 aa) | ||||
PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4134 aa) | ||||
BCL7C | BAF chromatin remodeling complex subunit BCL7C. (324 aa) | ||||
ENSCJAP00000073702 | Uncharacterized protein. (153 aa) | ||||
PARG | Poly(ADP-ribose) glycohydrolase. (976 aa) | ||||
ENSCJAP00000074162 | CtIP_N domain-containing protein. (468 aa) | ||||
ENSCJAP00000074278 | Endo/exonuclease/phosphatase domain-containing protein. (186 aa) | ||||
ENSCJAP00000074283 | DUF1725 domain-containing protein. (79 aa) | ||||
ENSCJAP00000074514 | Reverse transcriptase domain-containing protein. (251 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1210 aa) | ||||
ENSCJAP00000075018 | DUF1725 domain-containing protein. (128 aa) | ||||
ARID1B | AT-rich interaction domain 1B. (2420 aa) | ||||
ENSCJAP00000075323 | DUF4502 domain-containing protein. (122 aa) | ||||
ENSCJAP00000075433 | HMG box domain-containing protein. (137 aa) | ||||
ENSCJAP00000075493 | DUF1725 domain-containing protein. (103 aa) | ||||
ENSCJAP00000075765 | Uncharacterized protein. (260 aa) | ||||
BRCC3 | Lys-63-specific deubiquitinase BRCC36; Metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not have activity toward 'Lys-48'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX, antagonizing the RNF8-dependent ubiquitination at double- [...] (344 aa) | ||||
ENSCJAP00000076525 | Uncharacterized protein. (94 aa) | ||||
ENSCJAP00000076709 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (103 aa) | ||||
ENSCJAP00000076803 | FUS RNA binding protein. (607 aa) | ||||
ENSCJAP00000077244 | Uncharacterized protein. (89 aa) | ||||
ENSCJAP00000077268 | Uncharacterized protein. (146 aa) | ||||
ENSCJAP00000077481 | DUF4502 domain-containing protein. (67 aa) | ||||
ENSCJAP00000077645 | MOEP19 domain-containing protein. (161 aa) | ||||
KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (556 aa) | ||||
TAF4 | TATA-box binding protein associated factor 4. (1085 aa) | ||||
HDAC10 | Histone deacetylase 10. (695 aa) | ||||
ENSCJAP00000078638 | Uncharacterized protein. (134 aa) | ||||
PARPBP | PARP1 binding protein. (655 aa) |