STRINGSTRING
RNF112 RNF112 IL6ST IL6ST MTOR MTOR SOX8 SOX8 NKX6-1 NKX6-1 TTBK1 TTBK1 LRP2 LRP2 UFL1 UFL1 NKX6-2 NKX6-2 LIF LIF F6SK74_CALJA F6SK74_CALJA NOTCH1 NOTCH1 MDK MDK SERPINE2 SERPINE2 F7IMV6_CALJA F7IMV6_CALJA TNFRSF1B TNFRSF1B MECP2 MECP2 TENM4 TENM4 LOC100410496 LOC100410496 IL1B IL1B PRPF19 PRPF19 PLAG1 PLAG1 LYN LYN PTPRZ1 PTPRZ1 E2F1 E2F1 GSX2 GSX2 TGFB1 TGFB1 RHEB RHEB SHH SHH F7FT97_CALJA F7FT97_CALJA IL34 IL34 SYNJ1 SYNJ1 GJC2 GJC2 IL6 IL6 F7FS90_CALJA F7FS90_CALJA F7GTI5_CALJA F7GTI5_CALJA DICER1 DICER1 PPP1CC PPP1CC TNF TNF VEGFC VEGFC ENSCJAP00000053892 ENSCJAP00000053892 PTN PTN ZNF365 ZNF365 PRKCI PRKCI MAG MAG OLIG2 OLIG2 TP73 TP73 NTN1 NTN1 NTF3 NTF3 CLCF1 CLCF1 GFAP GFAP SPINT1 SPINT1 ENSCJAP00000067889 ENSCJAP00000067889 TSPO TSPO DAG1 DAG1 ENSCJAP00000070626 ENSCJAP00000070626 ASPA ASPA ENSCJAP00000072238 ENSCJAP00000072238 BMP2 BMP2 SOX10 SOX10 EGR2 EGR2 HDAC2 HDAC2 ZNF488 ZNF488 SLC7A5 SLC7A5 ACY3 ACY3 ENSCJAP00000077270 ENSCJAP00000077270 HDAC1 HDAC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RNF112RING finger protein 112. (631 aa)
IL6STInterleukin-6 receptor subunit beta isoform 1. (915 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
SOX8SRY-box transcription factor 8. (538 aa)
NKX6-1NK6 homeobox 1. (366 aa)
TTBK1Tau tubulin kinase 1. (1320 aa)
LRP2LDL receptor related protein 2. (4656 aa)
UFL1UFM1 specific ligase 1. (791 aa)
NKX6-2NK6 homeobox 2. (278 aa)
LIFLIF interleukin 6 family cytokine. (241 aa)
F6SK74_CALJAUncharacterized protein. (593 aa)
NOTCH1Notch receptor 1. (2551 aa)
MDKMidkine isoform a. (144 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
F7IMV6_CALJAUncharacterized protein. (146 aa)
TNFRSF1BTNF receptor superfamily member 1B. (462 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (497 aa)
TENM4Teneurin transmembrane protein 4. (2769 aa)
LOC100410496Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (268 aa)
PRPF19Pre-mRNA-processing factor 19. (504 aa)
PLAG1PLAG1 zinc finger. (500 aa)
LYNTyrosine-protein kinase. (491 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2279 aa)
E2F1E2F transcription factor 1. (439 aa)
GSX2GS homeobox 2. (305 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (477 aa)
F7FT97_CALJAHomeobox domain-containing protein. (286 aa)
IL34Interleukin 34. (242 aa)
SYNJ1Synaptojanin 1. (1610 aa)
GJC2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (439 aa)
IL6Interleukin 6. (212 aa)
F7FS90_CALJAUncharacterized protein. (314 aa)
F7GTI5_CALJAUncharacterized protein. (599 aa)
DICER1Endoribonuclease Dicer isoform 1; Belongs to the helicase family. Dicer subfamily. (1922 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (337 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (232 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (402 aa)
ENSCJAP00000053892BAR domain-containing protein. (420 aa)
PTNUncharacterized protein. (182 aa)
ZNF365Zinc finger protein 365. (436 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa)
MAGMyelin associated glycoprotein. (637 aa)
OLIG2Oligodendrocyte lineage transcription factor 2 (Predicted). (323 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (635 aa)
NTN1Netrin-1. (604 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (292 aa)
CLCF1Cardiotrophin-like cytokine factor 1 isoform 1. (225 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (504 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (531 aa)
ENSCJAP00000067889Hist_deacetyl domain-containing protein. (209 aa)
TSPOTranslocator protein. (203 aa)
DAG1Dystroglycan preproprotein. (895 aa)
ENSCJAP00000070626Uncharacterized protein. (225 aa)
ASPAAspartoacylase. (313 aa)
ENSCJAP00000072238Homeobox domain-containing protein. (270 aa)
BMP2Bone morphogenetic protein 2. (401 aa)
SOX10Transcription factor SOX-10. (467 aa)
EGR2Early growth response 2. (486 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (491 aa)
ZNF488Zinc finger protein 488. (233 aa)
SLC7A5Solute carrier family 7 member 5. (328 aa)
ACY3Aminoacylase 3. (202 aa)
ENSCJAP00000077270Homeobox domain-containing protein. (263 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (540 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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