STRINGSTRING
FZD9 FZD9 STK4 STK4 PRICKLE2 PRICKLE2 LEF1 LEF1 SOSTDC1 SOSTDC1 EDNRB EDNRB MAGI2 MAGI2 ENSCJAP00000059748 ENSCJAP00000059748 ETV2 ETV2 CSNK1G1 CSNK1G1 APC2 APC2 MCC MCC RYK RYK ENSCJAP00000061672 ENSCJAP00000061672 APCDD1 APCDD1 LOC100400880 LOC100400880 EDN1 EDN1 NKD2 NKD2 WNT2B WNT2B USP34 USP34 TCF7L1 TCF7L1 CSNK1A1L CSNK1A1L TLE1 TLE1 SHISA6 SHISA6 TRABD2B TRABD2B WWOX WWOX LDB1 LDB1 HIC1 HIC1 CCNY CCNY ENSCJAP00000064669 ENSCJAP00000064669 LGR6 LGR6 BARX1 BARX1 MBD2 MBD2 ENSCJAP00000065650 ENSCJAP00000065650 FZD2 FZD2 MARK4 MARK4 FRAT2 FRAT2 GPC4 GPC4 DISC1 DISC1 CTNNBIP1 CTNNBIP1 MESD MESD FZD1 FZD1 WNT4 WNT4 SOX9 SOX9 WNT9A WNT9A FZD10 FZD10 ENSCJAP00000068418 ENSCJAP00000068418 MED12 MED12 ENSCJAP00000068726 ENSCJAP00000068726 TGFB1I1 TGFB1I1 FOXO1 FOXO1 SIAH2 SIAH2 LRRK2 LRRK2 TMEM198 TMEM198 ENSCJAP00000069660 ENSCJAP00000069660 ENSCJAP00000070395 ENSCJAP00000070395 AMER2 AMER2 ENSCJAP00000071129 ENSCJAP00000071129 ENSCJAP00000071292 ENSCJAP00000071292 AMOTL1 AMOTL1 PLCG2 PLCG2 RSPO1 RSPO1 WNT3A WNT3A ENSCJAP00000071886 ENSCJAP00000071886 ENSCJAP00000071955 ENSCJAP00000071955 ENSCJAP00000071966 ENSCJAP00000071966 ENSCJAP00000072152 ENSCJAP00000072152 WNT7B WNT7B ENSCJAP00000072870 ENSCJAP00000072870 GRHL3 GRHL3 ENSCJAP00000073631 ENSCJAP00000073631 ENSCJAP00000073727 ENSCJAP00000073727 VPS35 VPS35 ENSCJAP00000073742 ENSCJAP00000073742 BMP2 BMP2 FZD8 FZD8 FGF9 FGF9 DKK2 DKK2 ENSCJAP00000075085 ENSCJAP00000075085 ENSCJAP00000075093 ENSCJAP00000075093 ENSCJAP00000075321 ENSCJAP00000075321 ENSCJAP00000075573 ENSCJAP00000075573 DACT3 DACT3 ENSCJAP00000075867 ENSCJAP00000075867 ENSCJAP00000076041 ENSCJAP00000076041 ENSCJAP00000076328 ENSCJAP00000076328 CDC73 CDC73 SOX17 SOX17 ENSCJAP00000076494 ENSCJAP00000076494 DKK1 DKK1 ENSCJAP00000076613 ENSCJAP00000076613 RNF146 RNF146 KLF4 KLF4 RSPO3 RSPO3 ENSCJAP00000077578 ENSCJAP00000077578 WNT16 WNT16 ENSCJAP00000077704 ENSCJAP00000077704 CELSR1 CELSR1 DVL3 DVL3 FOXD1 FOXD1 SENP2 SENP2 ENSCJAP00000078950 ENSCJAP00000078950 FRZB FRZB HMGXB4 HMGXB4 YAP1 YAP1 FZD4 FZD4 WNT5B WNT5B LEO1 LEO1 PPP1CA PPP1CA CYLD CYLD F7HFW4_CALJA F7HFW4_CALJA NKD1 NKD1 CCNE1 CCNE1 BRD7 BRD7 TMEM131L TMEM131L PYGO1 PYGO1 BCL9 BCL9 TNIK TNIK EDNRA EDNRA ADGRA2 ADGRA2 AMOTL2 AMOTL2 CELSR2 CELSR2 CSNK2B CSNK2B LY6G5B LY6G5B CELSR3 CELSR3 TLE4 TLE4 STRN STRN CCN4 CCN4 WNT2 WNT2 TMEM170B TMEM170B PTK7 PTK7 DVL1 DVL1 VANGL2 VANGL2 EXT1 EXT1 F7I8V5_CALJA F7I8V5_CALJA F7I8V2_CALJA F7I8V2_CALJA LGR4 LGR4 WNT8A WNT8A KLHL12 KLHL12 PKD2 PKD2 RSPO2 RSPO2 RTF1 RTF1 GRK6 GRK6 TLE3 TLE3 DLX3 DLX3 TAX1BP3 TAX1BP3 FERMT2 FERMT2 PRKAA1 PRKAA1 DAB2 DAB2 WNT5A WNT5A DKK4 DKK4 TNKS2 TNKS2 ARHGEF19 ARHGEF19 ARL6 ARL6 CTNND1 CTNND1 HHEX HHEX TIAM1 TIAM1 CHD8 CHD8 CTNND2 CTNND2 CPE CPE NDRG2 NDRG2 MYOC MYOC CCDC88A CCDC88A GID8 GID8 RECK RECK WDR61 WDR61 DAAM2 DAAM2 MACF1 MACF1 NDP NDP ISL1 ISL1 CTR9 CTR9 OTULIN OTULIN DIXDC1 DIXDC1 SFRP1 SFRP1 AMER3 AMER3 WNT6 WNT6 WNT10A WNT10A INVS INVS CSNK2A2 CSNK2A2 F6TG91_CALJA F6TG91_CALJA AXIN1 AXIN1 JUP JUP TNKS TNKS CUL3 CUL3 ZRANB1 ZRANB1 LRRFIP2 LRRFIP2 AMFR AMFR MITF MITF DRAXIN DRAXIN BCL9L BCL9L CCDC90B CCDC90B SDC1 SDC1 WIF1 WIF1 SLC9A3R1 SLC9A3R1 PIAS4 PIAS4 WNT11 WNT11 KREMEN2 KREMEN2 CDH3 CDH3 FZD3 FZD3 CXXC4 CXXC4 PLPP3 PLPP3 PRKAA2 PRKAA2 TLE5 TLE5 APC APC ROR1 ROR1 CTDNEP1 CTDNEP1 WNT3 WNT3 DVL2 DVL2 BCL7B BCL7B WNT7A WNT7A RNF43 RNF43 CSNK1G3 CSNK1G3 AXIN2 AXIN2 WLS WLS BTRC BTRC CELA1 CELA1 PRICKLE1 PRICKLE1 AMER1 AMER1 CCDC88C CCDC88C CTNNB1 CTNNB1 CSNK1D CSNK1D LRRC45 LRRC45 NOTUM NOTUM MARK2 MARK2 TLE2 TLE2 CALCOCO1 CALCOCO1 DAAM1 DAAM1 FBXW11 FBXW11 DDB1 DDB1 VAX2 VAX2 GRK5 GRK5 TRABD2A TRABD2A ZBED3 ZBED3 LRP4 LRP4 WNT9B WNT9B KREMEN1 KREMEN1 SHH SHH MARK1 MARK1 WNT10B WNT10B WNT1 WNT1 LMBR1L LMBR1L RSPO4 RSPO4 CSNK1A1 CSNK1A1 CPZ CPZ FZD5 FZD5 DACT1 DACT1 SIAH1 SIAH1 VANGL1 VANGL1 CDK14 CDK14 DDIT3 DDIT3 LATS2 LATS2 IFT80 IFT80 UBAC2 UBAC2 GSK3A GSK3A SFRP2 SFRP2 FZD6 FZD6 SCYL2 SCYL2 HBP1 HBP1 DKK3 DKK3 SFRP5 SFRP5 EPM2A EPM2A GSK3B GSK3B NLK NLK RARG RARG FBXW4 FBXW4 PORCN PORCN FGF10 FGF10 GATA3 GATA3 CCND1 CCND1 NXN NXN LRP6 LRP6 ENSCJAP00000054059 ENSCJAP00000054059 WNT8B WNT8B STK3 STK3 SMURF1 SMURF1 HESX1 HESX1 PTEN PTEN GSC GSC ENSCJAP00000054748 ENSCJAP00000054748 ZNRF3 ZNRF3 TCF7 TCF7 LZTS2 LZTS2 CCAR2 CCAR2 PAF1 PAF1 FZD7 FZD7 SFRP4 SFRP4 EDA EDA SMURF2 SMURF2 ENSCJAP00000057676 ENSCJAP00000057676 FAM53B FAM53B ENSCJAP00000057911 ENSCJAP00000057911 PYGO2 PYGO2 ENSCJAP00000058302 ENSCJAP00000058302
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
STK4Serine/threonine-protein kinase 4. (487 aa)
PRICKLE2Prickle planar cell polarity protein 2. (900 aa)
LEF1Lymphoid enhancer binding factor 1. (419 aa)
SOSTDC1CTCK domain-containing protein. (230 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (518 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1453 aa)
ENSCJAP00000059748DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (195 aa)
ETV2ETS variant 2. (370 aa)
CSNK1G1Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (474 aa)
APC2APC regulator of WNT signaling pathway 2. (2301 aa)
MCCUncharacterized protein. (1010 aa)
RYKReceptor like tyrosine kinase. (629 aa)
ENSCJAP00000061672Uncharacterized protein. (399 aa)
APCDD1APC down-regulated 1. (514 aa)
LOC100400880Uncharacterized protein C12orf43. (261 aa)
EDN1Endothelin-1 isoform 1 preproprotein. (213 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (400 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
USP34Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3545 aa)
TCF7L1HMG box domain-containing protein. (582 aa)
CSNK1A1LCasein kinase 1 alpha 1 like; Belongs to the protein kinase superfamily. (332 aa)
TLE1TLE family member 1, transcriptional corepressor. (804 aa)
SHISA6Shisa family member 6. (555 aa)
TRABD2BTraB domain containing 2B. (516 aa)
WWOXWW domain-containing oxidoreductase isoform 1. (414 aa)
LDB1LIM domain binding 1. (414 aa)
HIC1HIC ZBTB transcriptional repressor 1. (733 aa)
CCNYCyclin-Y isoform 1; Belongs to the cyclin family. (341 aa)
ENSCJAP00000064669Protein kinase domain-containing protein. (104 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (1075 aa)
BARX1BARX homeobox 1. (254 aa)
MBD2Methyl-CpG binding domain protein 2. (414 aa)
ENSCJAP00000065650Transcription factor 7 like 2. (649 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
MARK4Non-specific serine/threonine protein kinase. (752 aa)
FRAT2FRAT regulator of WNT signaling pathway 2. (230 aa)
GPC4Glypican-4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (556 aa)
DISC1Disrupted in schizophrenia 1 protein isoform L. (851 aa)
CTNNBIP1Beta-catenin-interacting protein 1. (81 aa)
MESDMesoderm development LRP chaperone. (232 aa)
FZD1Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (580 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (412 aa)
FZD10Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (582 aa)
ENSCJAP00000068418Uncharacterized protein. (85 aa)
MED12Mediator complex subunit 12. (2177 aa)
ENSCJAP00000068726TLE_N domain-containing protein. (118 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (469 aa)
FOXO1Fork-head domain-containing protein. (654 aa)
SIAH2E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (324 aa)
LRRK2Leucine rich repeat kinase 2. (2506 aa)
TMEM198Transmembrane protein 198. (446 aa)
ENSCJAP00000069660annotation not available (118 aa)
ENSCJAP00000070395GAIN domain-containing protein. (157 aa)
AMER2APC membrane recruitment protein 2 isoform 2. (550 aa)
ENSCJAP00000071129Fork-head domain-containing protein. (540 aa)
ENSCJAP00000071292Uncharacterized protein. (550 aa)
AMOTL1Angiomotin like 1. (986 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1288 aa)
RSPO1R-spondin 1. (281 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
ENSCJAP00000071886Uncharacterized protein. (155 aa)
ENSCJAP00000071955GAIN domain-containing protein. (152 aa)
ENSCJAP00000071966E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (306 aa)
ENSCJAP00000072152Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (274 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
ENSCJAP00000072870Uncharacterized protein. (383 aa)
GRHL3Grainyhead like transcription factor 3. (623 aa)
ENSCJAP00000073631Homeobox domain-containing protein. (202 aa)
ENSCJAP00000073727Uncharacterized protein. (122 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (804 aa)
ENSCJAP00000073742CDC73_N domain-containing protein. (390 aa)
BMP2Bone morphogenetic protein 2. (401 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (680 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (332 aa)
DKK2Dickkopf_N domain-containing protein. (259 aa)
ENSCJAP00000075085Uncharacterized protein. (120 aa)
ENSCJAP00000075093KA1 domain-containing protein. (73 aa)
ENSCJAP00000075321Ig-like domain-containing protein. (197 aa)
ENSCJAP00000075573Protein kinase domain-containing protein. (310 aa)
DACT3Dishevelled binding antagonist of beta catenin 3. (719 aa)
ENSCJAP00000075867Sclerostin. (213 aa)
ENSCJAP00000076041DUF4203 domain-containing protein. (191 aa)
ENSCJAP00000076328KA1 domain-containing protein. (73 aa)
CDC73Cell division cycle 73. (550 aa)
SOX17SRY-box transcription factor 17. (414 aa)
ENSCJAP00000076494E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (293 aa)
DKK1Dickkopf_N domain-containing protein. (332 aa)
ENSCJAP00000076613Uncharacterized protein. (435 aa)
RNF146E3 ubiquitin-protein ligase RNF146 isoform b. (359 aa)
KLF4Kruppel like factor 4. (507 aa)
RSPO3R-spondin-3. (273 aa)
ENSCJAP00000077578Kringle domain-containing protein. (125 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
ENSCJAP00000077704HMG box domain-containing protein. (262 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (1940 aa)
DVL3Dishevelled segment polarity protein 3. (750 aa)
FOXD1Forkhead box D1. (474 aa)
SENP2SUMO specific peptidase 2. (650 aa)
ENSCJAP00000078950RGS domain-containing protein. (164 aa)
FRZBFrizzled related protein. (412 aa)
HMGXB4HMG-box containing 4. (621 aa)
YAP1Yes associated protein 1. (507 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
WNT5BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (359 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (666 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
CYLDUbiquitin carboxyl-terminal hydrolase CYLD isoform 1; Belongs to the peptidase C19 family. (956 aa)
F7HFW4_CALJAUncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (852 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (549 aa)
CCNE1G1/S-specific cyclin-E1; Belongs to the cyclin family. (410 aa)
BRD7Bromodomain containing 7. (652 aa)
TMEM131LTransmembrane 131 like. (1610 aa)
PYGO1Pygopus family PHD finger 1. (420 aa)
BCL9BCL9 transcription coactivator. (1426 aa)
TNIKTRAF2 and NCK-interacting protein kinase isoform 1. (1360 aa)
EDNRAEndothelin-1 receptor isoform a; Belongs to the G-protein coupled receptor 1 family. (427 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1328 aa)
AMOTL2Angiomotin like 2. (835 aa)
CELSR2Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2929 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (234 aa)
LY6G5BLymphocyte antigen 6 family member G5B. (200 aa)
CELSR3Cadherin EGF LAG seven-pass G-type receptor 3; Belongs to the G-protein coupled receptor 2 family. (3318 aa)
TLE4TLE family member 4, transcriptional corepressor. (771 aa)
STRNStriatin. (780 aa)
CCN4Cellular communication network factor 4. (400 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
TMEM170BTransmembrane protein 170B. (132 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1075 aa)
DVL1Dishevelled segment polarity protein 1. (695 aa)
VANGL2Vang-like protein. (521 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
F7I8V5_CALJAUncharacterized protein. (74 aa)
F7I8V2_CALJAUncharacterized protein. (78 aa)
LGR4Leucine-rich repeat-containing G-protein coupled receptor 4. (951 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
KLHL12Kelch like family member 12. (638 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (973 aa)
RSPO2R-spondin-2. (243 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (712 aa)
GRK6G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (589 aa)
TLE3TLE family member 3, transcriptional corepressor. (829 aa)
DLX3Distal-less homeobox 3. (287 aa)
TAX1BP3Tax1-binding protein 3; May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. (124 aa)
FERMT2PH domain-containing protein. (687 aa)
PRKAA1Non-specific serine/threonine protein kinase. (574 aa)
DAB2Disabled homolog 2 isoform 1. (767 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
DKK4Dickkopf WNT signaling pathway inhibitor 4. (224 aa)
TNKS2Poly [ADP-ribose] polymerase. (1166 aa)
ARHGEF19Rho guanine nucleotide exchange factor 19. (805 aa)
ARL6ADP ribosylation factor like GTPase 6; Belongs to the small GTPase superfamily. Arf family. (272 aa)
CTNND1Catenin delta 1. (983 aa)
HHEXHematopoietically-expressed homeobox protein HHEX. (270 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1556 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2584 aa)
CTNND2Catenin delta-2. (1225 aa)
CPECarboxypeptidase E preproprotein. (476 aa)
NDRG2NDRG family member 2. (371 aa)
MYOCMyocilin. (504 aa)
CCDC88ACoiled-coil domain containing 88A. (1870 aa)
GID8Glucose-induced degradation protein 8 homolog. (228 aa)
RECKReversion-inducing cysteine-rich protein with Kazal motifs. (971 aa)
WDR61WD repeat-containing protein 61. (305 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1126 aa)
MACF1Microtubule actin crosslinking factor 1. (7595 aa)
NDPNorrin cystine knot growth factor NDP. (133 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
OTULINOTU deubiquitinase with linear linkage specificity. (352 aa)
DIXDC1DIX domain containing 1. (683 aa)
SFRP1Secreted frizzled-related protein 1. (314 aa)
AMER3APC membrane recruitment protein 3. (861 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
WNT10AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
INVSInversin. (1079 aa)
CSNK2A2Casein kinase II subunit alpha; Belongs to the protein kinase superfamily. (350 aa)
F6TG91_CALJAUncharacterized protein. (159 aa)
AXIN1Axin-1 isoform a. (867 aa)
JUPJunction plakoglobin. (745 aa)
TNKSPoly [ADP-ribose] polymerase. (1325 aa)
CUL3Cullin-3 isoform 1; Belongs to the cullin family. (768 aa)
ZRANB1Zinc finger RANBP2-type containing 1. (734 aa)
LRRFIP2Uncharacterized protein. (720 aa)
AMFRAutocrine motility factor receptor. (765 aa)
MITFMicrophthalmia-associated transcription factor isoform 1. (526 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (348 aa)
BCL9LB-cell CLL/lymphoma 9-like protein. (1497 aa)
CCDC90BCoiled-coil domain-containing protein 90B, mitochondrial. (254 aa)
SDC1Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (310 aa)
WIF1Wnt inhibitory factor 1. (379 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (358 aa)
PIAS4Protein inhibitor of activated STAT 4. (509 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (476 aa)
KREMEN2Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (462 aa)
CDH3Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (831 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (681 aa)
CXXC4CXXC finger protein 4. (373 aa)
PLPP3Lipid phosphate phosphohydrolase 3. (311 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
TLE5TLE family member 5, transcriptional modulator. (191 aa)
APCAdenomatous polyposis coli protein isoform b. (2842 aa)
ROR1Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
CTDNEP1CTD nuclear envelope phosphatase 1. (244 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2. (736 aa)
BCL7BB-cell CLL/lymphoma 7 protein family member B isoform 1. (202 aa)
WNT7AProtein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (349 aa)
RNF43E3 ubiquitin-protein ligase RNF43. (783 aa)
CSNK1G3Casein kinase I isoform gamma-3 isoform 4; Belongs to the protein kinase superfamily. (455 aa)
AXIN2Axin-2. (842 aa)
WLSProtein wntless homolog isoform 2. (545 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
CELA1Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (254 aa)
PRICKLE1Prickle planar cell polarity protein 1. (831 aa)
AMER1APC membrane recruitment protein 1. (1134 aa)
CCDC88CCoiled-coil domain containing 88C. (2029 aa)
CTNNB1Catenin beta 1. (774 aa)
CSNK1DCasein kinase 1 delta; Belongs to the protein kinase superfamily. (427 aa)
LRRC45Leucine-rich repeat-containing protein 45. (676 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (504 aa)
MARK2Non-specific serine/threonine protein kinase. (788 aa)
TLE2TLE family member 2, transcriptional corepressor. (745 aa)
CALCOCO1Calcium-binding and coiled-coil domain-containing protein 1 isoform 1. (691 aa)
DAAM1Disheveled-associated activator of morphogenesis 1 isoform 1. (1078 aa)
FBXW11F-box and WD repeat domain containing 11. (564 aa)
DDB1Damage specific DNA binding protein 1. (1140 aa)
VAX2Ventral anterior homeobox 2. (286 aa)
GRK5G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (590 aa)
TRABD2ATraB domain containing 2A. (505 aa)
ZBED3Zinc finger BED domain-containing protein 3. (231 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1905 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (491 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (477 aa)
MARK1Non-specific serine/threonine protein kinase. (824 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
LMBR1LLimb development membrane protein 1 like; Belongs to the LIMR family. (489 aa)
RSPO4R-spondin 4. (210 aa)
CSNK1A1Casein kinase I isoform alpha isoform 1; Belongs to the protein kinase superfamily. (365 aa)
CPZCarboxypeptidase Z. (643 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (837 aa)
SIAH1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (313 aa)
VANGL1Vang-like protein. (541 aa)
CDK14Cyclin-dependent kinase 14; Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuro [...] (469 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (169 aa)
LATS2Non-specific serine/threonine protein kinase. (1085 aa)
IFT80WD_REPEATS_REGION domain-containing protein. (777 aa)
UBAC2UBA domain containing 2. (392 aa)
GSK3AGlycogen synthase kinase-3 alpha; Belongs to the protein kinase superfamily. (483 aa)
SFRP2Secreted frizzled related protein 2. (538 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
SCYL2SCY1-like protein 2. (933 aa)
HBP1HMG-box transcription factor 1. (514 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (388 aa)
SFRP5Secreted frizzled related protein 5. (315 aa)
EPM2AEPM2A glucan phosphatase, laforin. (331 aa)
GSK3BGlycogen synthase kinase-3 beta isoform 1; Belongs to the protein kinase superfamily. (433 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
RARGRetinoic acid receptor gamma isoform 1. (454 aa)
FBXW4F-box and WD repeat domain containing 4. (616 aa)
PORCNPorcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (525 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
GATA3GATA binding protein 3. (444 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (531 aa)
NXNNucleoredoxin isoform 1. (437 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
ENSCJAP00000054059Ig-like domain-containing protein. (88 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
STK3Serine/threonine-protein kinase 3 isoform 1. (491 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
HESX1Homeobox expressed in ES cells 1. (185 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
GSCGoosecoid homeobox. (257 aa)
ENSCJAP00000054748Uncharacterized protein. (516 aa)
ZNRF3Zinc and ring finger 3. (933 aa)
TCF7Transcription factor 7. (512 aa)
LZTS2Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (669 aa)
CCAR2DBIRD complex subunit KIAA1967. (923 aa)
PAF1RNA polymerase II-associated factor 1 homolog isoform 1. (529 aa)
FZD7Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (620 aa)
SFRP4Secreted frizzled related protein 4. (346 aa)
EDATNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (389 aa)
SMURF2E3 ubiquitin-protein ligase. (748 aa)
ENSCJAP00000057676Protein kinase domain-containing protein. (217 aa)
FAM53BFamily with sequence similarity 53 member B. (422 aa)
ENSCJAP00000057911Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (81 aa)
PYGO2Pygopus family PHD finger 2. (405 aa)
ENSCJAP00000058302Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (330 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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