STRINGSTRING
WNT4 WNT4 TEAD2 TEAD2 SALL4 SALL4 LIAS LIAS IRX3 IRX3 KDM2B KDM2B SETD2 SETD2 APAF1 APAF1 SKI SKI HES5 HES5 SOX8 SOX8 PLXNB2 PLXNB2 FUZ FUZ IFT57 IFT57 OVOL2 OVOL2 PTK7 PTK7 DVL1 DVL1 LUZP1 LUZP1 VANGL2 VANGL2 HECTD1 HECTD1 LRP2 LRP2 LHX2 LHX2 HS2ST1 HS2ST1 OSR1 OSR1 GDF7 GDF7 RDH10 RDH10 WNT5A WNT5A GDNF GDNF SEMA4C SEMA4C TCTN1 TCTN1 ST14 ST14 HAND1 HAND1 KDF1 KDF1 TRAF6 TRAF6 SFRP1 SFRP1 ADM ADM WNT6 WNT6 ARHGAP35 ARHGAP35 TRIM71 TRIM71 DEAF1 DEAF1 TGFB2 TGFB2 EPB41L5 EPB41L5 MTHFR MTHFR MTHFD1L MTHFD1L RARA RARA COBL COBL GRSF1 GRSF1 SHROOM3 SHROOM3 KAT2A KAT2A TSC2 TSC2 FZD3 FZD3 GRHL2 GRHL2 SEC24B SEC24B RET RET NODAL NODAL RPS7 RPS7 DVL2 DVL2 ALDH1A3 ALDH1A3 CECR2 CECR2 IFT122 IFT122 GLMN GLMN FGF8 FGF8 PRICKLE1 PRICKLE1 CTNNB1 CTNNB1 SUFU SUFU TSC1 TSC1 BBS4 BBS4 TULP3 TULP3 HIF1A HIF1A CLUAP1 CLUAP1 TGFB1 TGFB1 MIB1 MIB1 F7F1K7_CALJA F7F1K7_CALJA TFAP2A TFAP2A BRD2 BRD2 PRKACB PRKACB F7IMR7_CALJA F7IMR7_CALJA SFRP2 SFRP2 FZD6 FZD6 KIF20B KIF20B MTHFD1 MTHFD1 RARG RARG DLC1 DLC1 TP63 TP63 VEGFC VEGFC FGF10 FGF10 GATA3 GATA3 LOC100407817 LOC100407817 NOG NOG SIX1 SIX1 STK3 STK3 ENSCJAP00000054910 ENSCJAP00000054910 ENSCJAP00000055055 ENSCJAP00000055055 CITED2 CITED2 STIL STIL PTCH1 PTCH1 ALDH1A2 ALDH1A2 STK4 STK4 TBX18 TBX18 KDM6A KDM6A OPA1 OPA1 MKS1 MKS1 RGMA RGMA PHACTR4 PHACTR4 ENSCJAP00000064207 ENSCJAP00000064207 FGFR2 FGFR2 SOX11 SOX11 FZD2 FZD2 PCDH8 PCDH8 PAX2 PAX2 ABL1 ABL1 IRX1 IRX1 TMED2 TMED2 SOX4 SOX4 RALA RALA SPINT1 SPINT1 SOX9 SOX9 ENSCJAP00000068422 ENSCJAP00000068422 ENSCJAP00000068453 ENSCJAP00000068453 IRX2 IRX2 MED12 MED12 TGFB1I1 TGFB1I1 ENSCJAP00000068847 ENSCJAP00000068847 ENSCJAP00000069135 ENSCJAP00000069135 ENSCJAP00000069517 ENSCJAP00000069517 ENSCJAP00000069678 ENSCJAP00000069678 ENSCJAP00000069733 ENSCJAP00000069733 BMP4 BMP4 ENSCJAP00000070395 ENSCJAP00000070395 BMP7 BMP7 ENSCJAP00000070967 ENSCJAP00000070967 ENSCJAP00000071558 ENSCJAP00000071558 SHANK3 SHANK3 ENSCJAP00000071955 ENSCJAP00000071955 IFT52 IFT52 WNT7B WNT7B ENSCJAP00000072423 ENSCJAP00000072423 ENSCJAP00000072466 ENSCJAP00000072466 ENSCJAP00000072853 ENSCJAP00000072853 GRHL3 GRHL3 CC2D2A CC2D2A BMP5 BMP5 PDX1 PDX1 TBXT TBXT VASP VASP SDC4 SDC4 SCRIB SCRIB BCL10 BCL10 LRRC1 LRRC1 ENSCJAP00000077181 ENSCJAP00000077181 WNT16 WNT16 CELSR1 CELSR1 LMO4 LMO4 DVL3 DVL3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
TEAD2TEA domain transcription factor 2. (320 aa)
SALL4Uncharacterized protein. (986 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa)
IRX3Iroquois homeobox 3. (501 aa)
KDM2BLysine demethylase 2B. (1246 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2561 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1249 aa)
SKISKI proto-oncogene. (729 aa)
HES5Hes family bHLH transcription factor 5. (162 aa)
SOX8SRY-box transcription factor 8. (538 aa)
PLXNB2Plexin-B2. (1839 aa)
FUZFuzzy planar cell polarity protein. (418 aa)
IFT57Intraflagellar transport 57. (416 aa)
OVOL2Transcription factor Ovo-like 2. (275 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1075 aa)
DVL1Dishevelled segment polarity protein 1. (695 aa)
LUZP1Leucine zipper protein 1. (1074 aa)
VANGL2Vang-like protein. (521 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2610 aa)
LRP2LDL receptor related protein 2. (4656 aa)
LHX2LIM/homeobox protein Lhx2. (406 aa)
HS2ST1Heparan sulfate 2-O-sulfotransferase 1 isoform 1. (356 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
GDF7Growth differentiation factor 7. (449 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
GDNFGlial cell derived neurotrophic factor. (228 aa)
SEMA4CSemaphorin-4C; Belongs to the semaphorin family. (833 aa)
TCTN1Tectonic family member 1. (592 aa)
ST14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa)
HAND1Heart and neural crest derivatives expressed 1. (224 aa)
KDF1Keratinocyte differentiation factor 1. (398 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (537 aa)
SFRP1Secreted frizzled-related protein 1. (314 aa)
ADMAdrenomedullin. (187 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
ARHGAP35Rho GTPase activating protein 35. (1499 aa)
TRIM71Tripartite motif containing 71. (868 aa)
DEAF1DEAF1 transcription factor. (418 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
EPB41L5Band 4.1-like protein 5 isoform 1. (733 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (697 aa)
MTHFD1LMethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like. (979 aa)
RARAUncharacterized protein. (468 aa)
COBLCordon-bleu WH2 repeat protein. (1274 aa)
GRSF1G-rich RNA sequence binding factor 1. (505 aa)
SHROOM3Shroom family member 3. (1995 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
TSC2TSC complex subunit 2. (1794 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (681 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1269 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1115 aa)
NODALNodal growth differentiation factor. (346 aa)
RPS740S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2. (736 aa)
ALDH1A3Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (512 aa)
CECR2CECR2 histone acetyl-lysine reader. (1484 aa)
IFT122Intraflagellar transport 122. (1238 aa)
GLMNGlomulin, FKBP associated protein. (595 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
PRICKLE1Prickle planar cell polarity protein 1. (831 aa)
CTNNB1Catenin beta 1. (774 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (485 aa)
TSC1Hamartin isoform 3. (1168 aa)
BBS4Bardet-Biedl syndrome 4. (518 aa)
TULP3TUB like protein 3; Belongs to the TUB family. (501 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (850 aa)
CLUAP1Clusterin associated protein 1. (432 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
F7F1K7_CALJAUncharacterized protein. (277 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
BRD2Uncharacterized protein. (772 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform 1; Belongs to the protein kinase superfamily. (398 aa)
F7IMR7_CALJAUncharacterized protein. (795 aa)
SFRP2Secreted frizzled related protein 2. (538 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
KIF20BKinesin family member 20B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1820 aa)
MTHFD1Uncharacterized protein. (964 aa)
RARGRetinoic acid receptor gamma isoform 1. (454 aa)
DLC1DLC1 Rho GTPase activating protein. (1528 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (402 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
GATA3GATA binding protein 3. (444 aa)
LOC100407817WH1 domain-containing protein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (380 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SIX1Homeobox protein SIX1. (284 aa)
STK3Serine/threonine-protein kinase 3 isoform 1. (491 aa)
ENSCJAP00000054910Uncharacterized protein. (406 aa)
ENSCJAP0000005505540S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
CITED2Uncharacterized protein. (273 aa)
STILSTIL centriolar assembly protein. (1287 aa)
PTCH1Protein patched homolog 1 isoform L. (1449 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
STK4Serine/threonine-protein kinase 4. (487 aa)
TBX18T-box transcription factor 18. (607 aa)
KDM6ALysine demethylase 6A. (1429 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1019 aa)
MKS1Meckel syndrome type 1 protein isoform 1. (559 aa)
RGMARepulsive guidance molecule BMP co-receptor a. (513 aa)
PHACTR4Phosphatase and actin regulator. (713 aa)
ENSCJAP0000006420740S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
FGFR2Fibroblast growth factor receptor. (822 aa)
SOX11Transcription factor SOX. (448 aa)
FZD2Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (565 aa)
PCDH8Protocadherin-8 isoform 1. (1070 aa)
PAX2Paired box 2. (448 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
IRX1Iroquois homeobox 1. (480 aa)
TMED2Transmembrane emp24 domain-containing protein 2. (208 aa)
SOX4Transcription factor SOX. (472 aa)
RALARAS like proto-oncogene A. (206 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (531 aa)
SOX9Transcription factor SOX-9; Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219. (509 aa)
ENSCJAP00000068422LIAS_N domain-containing protein. (158 aa)
ENSCJAP0000006845340S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (180 aa)
IRX2Iroquois homeobox 2. (501 aa)
MED12Mediator complex subunit 12. (2177 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (469 aa)
ENSCJAP0000006884740S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (130 aa)
ENSCJAP0000006913540S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (162 aa)
ENSCJAP00000069517Uncharacterized protein. (251 aa)
ENSCJAP0000006967840S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (180 aa)
ENSCJAP00000069733Uncharacterized protein. (164 aa)
BMP4Bone morphogenetic protein 4 preproprotein. (408 aa)
ENSCJAP00000070395GAIN domain-containing protein. (157 aa)
BMP7Bone morphogenetic protein 7. (430 aa)
ENSCJAP00000070967Folate_rec domain-containing protein. (232 aa)
ENSCJAP00000071558TGF_BETA_2 domain-containing protein. (151 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1897 aa)
ENSCJAP00000071955GAIN domain-containing protein. (152 aa)
IFT52Intraflagellar transport 52. (442 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
ENSCJAP0000007242340S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (180 aa)
ENSCJAP0000007246640S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (125 aa)
ENSCJAP00000072853EGF-like domain-containing protein. (147 aa)
GRHL3Grainyhead like transcription factor 3. (623 aa)
CC2D2ACoiled-coil and C2 domain containing 2A. (1583 aa)
BMP5Bone morphogenetic protein 5. (472 aa)
PDX1Homeobox domain-containing protein. (282 aa)
TBXTT-box transcription factor T. (448 aa)
VASPWH1 domain-containing protein. (485 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (233 aa)
SCRIBUncharacterized protein. (1686 aa)
BCL10B-cell lymphoma/leukemia 10. (233 aa)
LRRC1Leucine-rich repeat-containing protein 1. (524 aa)
ENSCJAP0000007718140S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (120 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (1940 aa)
LMO4Uncharacterized protein. (218 aa)
DVL3Dishevelled segment polarity protein 3. (750 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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