STRINGSTRING
STAT3 STAT3 STAT5B STAT5B PIK3CD PIK3CD KDELR1 KDELR1 CCR6 CCR6 ARMC5 ARMC5 FADD FADD LCK LCK ERBB2 ERBB2 CCR9 CCR9 MTOR MTOR LOC100403511 LOC100403511 IL21 IL21 RORA RORA MR1 MR1 TRAF3IP2 TRAF3IP2 SRF SRF SEMA4A SEMA4A SYK SYK PAX1 PAX1 ATG5 ATG5 ADAM17 ADAM17 RIPK3 RIPK3 PRR7 PRR7 PTGER4 PTGER4 GLI3 GLI3 SP3 SP3 F7HUV6_CALJA F7HUV6_CALJA ATF2 ATF2 IL18R1 IL18R1 CHD7 CHD7 RC3H1 RC3H1 LOC100405020 LOC100405020 F6PHH9_CALJA F6PHH9_CALJA PATZ1 PATZ1 RAG2 RAG2 XRCC4 XRCC4 NHEJ1 NHEJ1 ZAP70 ZAP70 F6TT07_CALJA F6TT07_CALJA FOXN1 FOXN1 ZFPM1 ZFPM1 FUT7 FUT7 ITPKB ITPKB RELB RELB CD3D CD3D FOXP1 FOXP1 CCR7 CCR7 AIRE AIRE PIK3R2 PIK3R2 DOCK2 DOCK2 BCL6 BCL6 TMEM98 TMEM98 ZFP36L2 ZFP36L2 CLEC4G CLEC4G PREX1 PREX1 SOX13 SOX13 LEPR LEPR NKX2-3 NKX2-3 ENTPD7 ENTPD7 ADA ADA LEP LEP CTNNB1 CTNNB1 TSC1 TSC1 IL7R IL7R ITK ITK CLEC4E CLEC4E CLEC4D CLEC4D CRACR2A CRACR2A IL12B IL12B TESPA1 TESPA1 NCAPH2 NCAPH2 CD8A CD8A RHOH RHOH IRF4 IRF4 DNAJA3 DNAJA3 RC3H2 RC3H2 TGFB1 TGFB1 SHH SHH F7IBT5_CALJA F7IBT5_CALJA WNT10B WNT10B WNT1 WNT1 LMBR1L LMBR1L PIK3R3 PIK3R3 FZD5 FZD5 PGBD4 PGBD4 F7HF06_CALJA F7HF06_CALJA PTPN22 PTPN22 VAV1 VAV1 CD4 CD4 ZBTB7B ZBTB7B PTPRC PTPRC THEMIS THEMIS IL6 IL6 B2M B2M SASH3 SASH3 LIG4 LIG4 IKZF3 IKZF3 ZBTB1 ZBTB1 EOMES EOMES BATF BATF IL6R IL6R GATA3 GATA3 RPS6 RPS6 ENSCJAP00000053832 ENSCJAP00000053832 KIT KIT ENSCJAP00000054380 ENSCJAP00000054380 STK11 STK11 ENSCJAP00000054854 ENSCJAP00000054854 IL15 IL15 TCF7 TCF7 ENSCJAP00000056467 ENSCJAP00000056467 ENSCJAP00000056719 ENSCJAP00000056719 BCL11B BCL11B FOXP3 FOXP3 CD3E CD3E LEF1 LEF1 BCL3 BCL3 IRF1 IRF1 CD83 CD83 BRAF BRAF DLL4 DLL4 RABL3 RABL3 JMJD6 JMJD6 RAG1 RAG1 TOX TOX CDK6 CDK6 PPP3CB PPP3CB PKNOX1 PKNOX1 ATP7A ATP7A CTSL CTSL RIPK2 RIPK2 NRARP NRARP ENSCJAP00000066295 ENSCJAP00000066295 BCL2 BCL2 ABL1 ABL1 IL7 IL7 SOX4 SOX4 TBX21 TBX21 CD74 CD74 TNFSF8 TNFSF8 WNT4 WNT4 ENSCJAP00000067771 ENSCJAP00000067771 CD28 CD28 ANXA1 ANXA1 ENSCJAP00000068998 ENSCJAP00000068998 RSAD2 RSAD2 LY9 LY9 GPR18 GPR18 ENSCJAP00000072171 ENSCJAP00000072171 ENSCJAP00000072280 ENSCJAP00000072280 PRKDC PRKDC STAT6 STAT6 ENSCJAP00000072853 ENSCJAP00000072853 ENSCJAP00000073490 ENSCJAP00000073490 ENSCJAP00000073690 ENSCJAP00000073690 ZFP36L1 ZFP36L1 FZD8 FZD8 PSMB11 PSMB11 RUNX2 RUNX2 RORC RORC EGR1 EGR1 ENSCJAP00000076601 ENSCJAP00000076601 PLA2G2D PLA2G2D IL2RG IL2RG ENSCJAP00000078626 ENSCJAP00000078626 CARD11 CARD11 PTPN2 PTPN2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STAT3Signal transducer and activator of transcription. (771 aa)
STAT5BSignal transducer and activator of transcription. (792 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
KDELR1ER lumen protein-retaining receptor. (149 aa)
CCR6C-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (377 aa)
ARMC5Armadillo repeat containing 5. (1028 aa)
FADDFas associated via death domain. (284 aa)
LCKTyrosine-protein kinase. (539 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (369 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
LOC100403511Golgi pH regulator A isoform 1. (455 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
RORARAR related orphan receptor A. (486 aa)
MR1Major histocompatibility complex, class I-related; Belongs to the MHC class I family. (337 aa)
TRAF3IP2TRAF3 interacting protein 2. (552 aa)
SRFSerum response factor. (509 aa)
SEMA4ASemaphorin-4A isoform 1; Belongs to the semaphorin family. (761 aa)
SYKUncharacterized protein. (636 aa)
PAX1Paired box 1. (454 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
ADAM17Disintegrin and metalloproteinase domain-containing protein 17 preproprotein. (824 aa)
RIPK3Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily. (475 aa)
PRR7Proline rich 7, synaptic. (272 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
GLI3GLI family zinc finger 3. (1578 aa)
SP3Sp3 transcription factor. (782 aa)
F7HUV6_CALJANR LBD domain-containing protein. (161 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
IL18R1Interleukin-18 receptor 1. (539 aa)
CHD7Chromodomain-helicase-DNA-binding protein 7. (2994 aa)
RC3H1Ring finger and CCCH-type domains 1. (1133 aa)
LOC100405020AIG1-type G domain-containing protein. (307 aa)
F6PHH9_CALJAAIG1-type G domain-containing protein. (353 aa)
PATZ1POZ and AT hook containing zinc finger 1 long C isoform (Predicted). (687 aa)
RAG2Recombination activating 2. (527 aa)
XRCC4DNA repair protein XRCC4 isoform 1. (334 aa)
NHEJ1Uncharacterized protein. (317 aa)
ZAP70Zeta chain of T cell receptor associated protein kinase 70. (648 aa)
F6TT07_CALJADHR-1 domain-containing protein; Belongs to the DOCK family. (726 aa)
FOXN1Forkhead box N1. (647 aa)
ZFPM1Zinc finger protein, FOG family member 1. (992 aa)
FUT7Fucosyltransferase 7. (342 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (947 aa)
RELBRELB proto-oncogene, NF-kB subunit. (575 aa)
CD3DIg_4 domain-containing protein. (283 aa)
FOXP1Fork-head domain-containing protein. (693 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
AIREAutoimmune regulator. (392 aa)
PIK3R2Phosphatidylinositol 3-kinase regulatory subunit beta. (727 aa)
DOCK2DHR-2 domain-containing protein; Belongs to the DOCK family. (1122 aa)
BCL6B-cell lymphoma 6 protein isoform 1. (706 aa)
TMEM98Transmembrane protein 98. (226 aa)
ZFP36L2Zinc finger protein 36, C3H1 type-like 2. (495 aa)
CLEC4GC-type lectin domain family 4 member G. (287 aa)
PREX1Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein. (1651 aa)
SOX13SRY-box transcription factor 13. (615 aa)
LEPRLeptin receptor. (1165 aa)
NKX2-3NK2 homeobox 3. (363 aa)
ENTPD7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (604 aa)
ADAAdenosine deaminase. (363 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
CTNNB1Catenin beta 1. (774 aa)
TSC1Hamartin isoform 3. (1168 aa)
IL7RInterleukin-7 receptor subunit alpha; Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP) (By similarity); Belongs to the type I cytokine receptor family. Type 4 subfamily. (459 aa)
ITKTyrosine-protein kinase. (620 aa)
CLEC4EC-type lectin domain family 4 member E. (219 aa)
CLEC4DC-type lectin domain family 4 member D. (217 aa)
CRACR2ACalcium release activated channel regulator 2A. (731 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (328 aa)
TESPA1Thymocyte expressed, positive selection associated 1. (522 aa)
NCAPH2Non-SMC condensin II complex subunit H2. (612 aa)
CD8ACD8a molecule. (236 aa)
RHOHRas homolog family member H. (191 aa)
IRF4Interferon regulatory factor 4. (451 aa)
DNAJA3DnaJ homolog subfamily A member 3, mitochondrial isoform 1. (480 aa)
RC3H2RING finger and CCCH-type zinc finger domain-containing protein 2 isoform 1. (1191 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (477 aa)
F7IBT5_CALJAUncharacterized protein. (202 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
LMBR1LLimb development membrane protein 1 like; Belongs to the LIMR family. (489 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
PGBD4PiggyBac transposable element derived 4. (585 aa)
F7HF06_CALJA40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (231 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (810 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
CD4Ig-like domain-containing protein. (457 aa)
ZBTB7BZinc finger and BTB domain-containing protein 7B isoform 2. (573 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1252 aa)
THEMISThymocyte selection associated. (641 aa)
IL6Interleukin 6. (212 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (119 aa)
SASH3SAM and SH3 domain-containing protein 3. (380 aa)
LIG4DNA ligase. (911 aa)
IKZF3IKAROS family zinc finger 3. (509 aa)
ZBTB1Zinc finger and BTB domain containing 1. (644 aa)
EOMESEomesodermin. (706 aa)
BATFBasic leucine zipper transcriptional factor ATF-like. (125 aa)
IL6RUncharacterized protein. (468 aa)
GATA3GATA binding protein 3. (444 aa)
RPS640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa)
ENSCJAP00000053832Uncharacterized protein. (81 aa)
KITMast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Phosphorylates PIK3R1, PLCG1, SH2B2/APS and CBL. Activates the AKT1 signaling pathway by phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Activat [...] (976 aa)
ENSCJAP00000054380annotation not available (98 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
ENSCJAP0000005485440S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (218 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (162 aa)
TCF7Transcription factor 7. (512 aa)
ENSCJAP00000056467Uncharacterized protein. (99 aa)
ENSCJAP00000056719Beta-1,3-N-acetylglucosaminyltransferase. (381 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (938 aa)
FOXP3Forkhead box P3. (478 aa)
CD3ECD3e molecule. (232 aa)
LEF1Lymphoid enhancer binding factor 1. (419 aa)
BCL3BCL3 transcription coactivator. (454 aa)
IRF1Interferon regulatory factor. (324 aa)
CD83CD83 antigen isoform a. (201 aa)
BRAFUncharacterized protein. (805 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (718 aa)
RABL3RAB, member of RAS oncogene family like 3. (255 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (414 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
TOXThymocyte selection-associated high mobility group box protein TOX. (526 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
PKNOX1PBX/knotted 1 homeobox 1. (437 aa)
ATP7AATPase copper transporting alpha. (1500 aa)
CTSLUncharacterized protein; Belongs to the peptidase C1 family. (348 aa)
RIPK2Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (539 aa)
NRARPNotch-regulated ankyrin repeat-containing protein. (114 aa)
ENSCJAP00000066295Uncharacterized protein. (213 aa)
BCL2BCL2 apoptosis regulator. (240 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (177 aa)
SOX4Transcription factor SOX. (472 aa)
TBX21T-box transcription factor 21. (537 aa)
CD74CD74 molecule. (300 aa)
TNFSF8Tumor necrosis factor ligand 3A; Belongs to the tumor necrosis factor family. (234 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
ENSCJAP00000067771Uncharacterized protein. (78 aa)
CD28IGv domain-containing protein. (234 aa)
ANXA1Annexin. (403 aa)
ENSCJAP0000006899840S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (231 aa)
RSAD2Radical S-adenosyl methionine domain-containing protein 2. (361 aa)
LY9Lymphocyte antigen 9. (656 aa)
GPR18G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. (319 aa)
ENSCJAP00000072171Uncharacterized protein. (145 aa)
ENSCJAP00000072280Uncharacterized protein. (107 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4134 aa)
STAT6Signal transducer and activator of transcription. (865 aa)
ENSCJAP00000072853EGF-like domain-containing protein. (147 aa)
ENSCJAP00000073490Uncharacterized protein. (98 aa)
ENSCJAP00000073690Uncharacterized protein; Belongs to the peptidase C1 family. (313 aa)
ZFP36L1Uncharacterized protein. (338 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (680 aa)
PSMB11Proteasome subunit beta. (231 aa)
RUNX2RUNX family transcription factor 2. (645 aa)
RORCUncharacterized protein. (262 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (542 aa)
ENSCJAP00000076601Uncharacterized protein. (127 aa)
PLA2G2DPhospholipase A(2). (145 aa)
IL2RGFibronectin type-III domain-containing protein. (374 aa)
ENSCJAP00000078626Uncharacterized protein. (158 aa)
CARD11Caspase recruitment domain-containing protein 11. (1154 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (429 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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