STRINGSTRING
ALX4 ALX4 ZBTB16 ZBTB16 TGFB2 TGFB2 MYH3 MYH3 HNF1A HNF1A FGF4 FGF4 PSEN1 PSEN1 TMEM107 TMEM107 IFT140 IFT140 CHST11 CHST11 FRAS1 FRAS1 FLVCR1 FLVCR1 GRHL2 GRHL2 ACD ACD IMPAD1 IMPAD1 WNT3 WNT3 WNT7A WNT7A FGF8 FGF8 GDF5 GDF5 FREM2 FREM2 CTNNB1 CTNNB1 CPLANE1 CPLANE1 NIPBL NIPBL GNA12 GNA12 TULP3 TULP3 HOXC11 HOXC11 HOXA10 HOXA10 FBN2 FBN2 CREBBP CREBBP LRP4 LRP4 SHH SHH F7F1K7_CALJA F7F1K7_CALJA TFAP2A TFAP2A ECE1 ECE1 SFRP2 SFRP2 FZD6 FZD6 BMPR1A BMPR1A RARG RARG FBXW4 FBXW4 TP63 TP63 HOXD9 HOXD9 DLX6 DLX6 NOG NOG EN1 EN1 IHH IHH B9D1 B9D1 C2CD3 C2CD3 MBNL1 MBNL1 HOXD13 HOXD13 SMAD4 SMAD4 PTCH1 PTCH1 ALDH1A2 ALDH1A2 LEF1 LEF1 MKS1 MKS1 NOTCH2 NOTCH2 BAX BAX HOXA13 HOXA13 HOXD12 HOXD12 SHOX2 SHOX2 ZNF358 ZNF358 HOXC10 HOXC10 MEGF8 MEGF8 ENSCJAP00000067889 ENSCJAP00000067889 ENSCJAP00000067921 ENSCJAP00000067921 PITX1 PITX1 BMP4 BMP4 BMP7 BMP7 ENSCJAP00000071558 ENSCJAP00000071558 LOC103787209 LOC103787209 OSR2 OSR2 ENSCJAP00000071886 ENSCJAP00000071886 IFT52 IFT52 ENSCJAP00000072850 ENSCJAP00000072850 HDAC2 HDAC2 FGF9 FGF9 HAND2 HAND2 RUNX2 RUNX2 ALX3 ALX3 DKK1 DKK1 HDAC1 HDAC1 MSX1 MSX1 NOTCH1 NOTCH1 RECK RECK PRRX1 PRRX1 TBX5 TBX5 TBX3 TBX3 DYNC2H1 DYNC2H1 CHD7 CHD7 MED1 MED1 HOXD10 HOXD10 HOXA11 HOXA11 MAP3K20 MAP3K20 WNT5A WNT5A GLI3 GLI3 RDH10 RDH10 OSR1 OSR1 WDPCP WDPCP RSPO2 RSPO2 CRABP2 CRABP2 BCL2L11 BCL2L11 LMBR1 LMBR1 FUZ FUZ RARB RARB CYP26B1 CYP26B1 INTU INTU SKI SKI TBC1D32 TBC1D32 PBX2 PBX2 SALL1 SALL1 RPGRIP1L RPGRIP1L TBX4 TBX4 TBX2 TBX2 SP8 SP8 CACNA1C CACNA1C WDR19 WDR19 SALL4 SALL4 DLX5 DLX5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALX4ALX homeobox 4. (403 aa)
ZBTB16Zinc finger and BTB domain-containing protein 16. (673 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
MYH3Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1811 aa)
HNF1AHNF1 homeobox A. (638 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (466 aa)
TMEM107Transmembrane protein 107 isoform 2. (140 aa)
IFT140Intraflagellar transport 140. (1460 aa)
CHST11Carbohydrate sulfotransferase. (352 aa)
FRAS1Fraser extracellular matrix complex subunit 1. (4011 aa)
FLVCR1Feline leukemia virus subgroup C receptor-related protein 1. (555 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
ACDACD shelterin complex subunit and telomerase recruitment factor. (480 aa)
IMPAD1Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase; Exhibits 3'-nucleotidase activity toward adenosine 3',5'- bisphosphate (PAP), namely hydrolyzes adenosine 3',5'-bisphosphate into adenosine 5'-monophosphate (AMP) and a phosphate. May play a role in the formation of skeletal elements derived through endochondral ossification, possibly by clearing adenosine 3',5'-bisphosphate produced by Golgi sulfotransferases during glycosaminoglycan sulfation. Has no activity toward 3'-phosphoadenosine 5'-phosphosulfate (PAPS) or inositol phosphate (IP) substrates including I(1)P, I(1,4)P2, [...] (358 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
WNT7AProtein Wnt-7a; Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta- catenin signaling pathway (By similarity). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development. Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (By similarity). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes. Required for normal [...] (349 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
GDF5Growth differentiation factor 5. (501 aa)
FREM2FRAS1 related extracellular matrix 2. (3170 aa)
CTNNB1Catenin beta 1. (774 aa)
CPLANE1Ciliogenesis and planar polarity effector 1. (3199 aa)
NIPBLNipped-B protein. (2804 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12. (380 aa)
TULP3TUB like protein 3; Belongs to the TUB family. (501 aa)
HOXC11Homeobox C11. (304 aa)
HOXA10Homeobox domain-containing protein. (94 aa)
FBN2Fibrillin 2. (2912 aa)
CREBBPCREB-binding protein isoform a. (2449 aa)
LRP4Low-density lipoprotein receptor-related protein 4. (1905 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (477 aa)
F7F1K7_CALJAUncharacterized protein. (277 aa)
TFAP2ATranscription factor AP-2 alpha. (439 aa)
ECE1Endothelin converting enzyme 1. (845 aa)
SFRP2Secreted frizzled related protein 2. (538 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
RARGRetinoic acid receptor gamma isoform 1. (454 aa)
FBXW4F-box and WD repeat domain containing 4. (616 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
HOXD9Homeobox D9. (342 aa)
DLX6Distal-less homeobox 6. (291 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
EN1Homeobox protein engrailed-like. (391 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
B9D1B9 domain-containing protein 1 isoform b. (204 aa)
C2CD3C2 domain containing 3 centriole elongation regulator. (2352 aa)
MBNL1Muscleblind-like protein 1 isoform c. (399 aa)
HOXD13Homeobox protein Hox-D13. (344 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
PTCH1Protein patched homolog 1 isoform L. (1449 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
LEF1Lymphoid enhancer binding factor 1. (419 aa)
MKS1Meckel syndrome type 1 protein isoform 1. (559 aa)
NOTCH2Notch receptor 2. (2470 aa)
BAXBCL2 associated X, apoptosis regulator. (193 aa)
HOXA13Homeobox A13. (385 aa)
HOXD12Homeobox D12. (270 aa)
SHOX2Short stature homeobox 2. (319 aa)
ZNF358Zinc finger protein 358. (624 aa)
HOXC10Homeobox C10. (347 aa)
MEGF8Uncharacterized protein. (440 aa)
ENSCJAP00000067889Hist_deacetyl domain-containing protein. (209 aa)
ENSCJAP00000067921Sp9 transcription factor. (482 aa)
PITX1Homeobox protein. (314 aa)
BMP4Bone morphogenetic protein 4 preproprotein. (408 aa)
BMP7Bone morphogenetic protein 7. (430 aa)
ENSCJAP00000071558TGF_BETA_2 domain-containing protein. (151 aa)
LOC103787209Protein NESP55 isoform NESP55. (253 aa)
OSR2Protein odd-skipped-related 2 isoform b. (276 aa)
ENSCJAP00000071886Uncharacterized protein. (155 aa)
IFT52Intraflagellar transport 52. (442 aa)
ENSCJAP00000072850Homeobox domain-containing protein. (229 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (491 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (332 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
RUNX2RUNX family transcription factor 2. (645 aa)
ALX3ALX homeobox 3. (462 aa)
DKK1Dickkopf_N domain-containing protein. (332 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (540 aa)
MSX1Homeobox protein MSX-1; Acts as a transcriptional repressor. May play a role in limb- pattern formation. Acts in cranofacial development and specifically in odontogenesis (By similarity). (303 aa)
NOTCH1Notch receptor 1. (2551 aa)
RECKReversion-inducing cysteine-rich protein with Kazal motifs. (971 aa)
PRRX1Paired related homeobox 1. (245 aa)
TBX5T-box transcription factor TBX5 isoform 1. (518 aa)
TBX3T-box transcription factor TBX3 isoform 2. (743 aa)
DYNC2H1Dynein cytoplasmic 2 heavy chain 1. (4146 aa)
CHD7Chromodomain-helicase-DNA-binding protein 7. (2994 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1580 aa)
HOXD10Homeobox protein Hox-D10. (340 aa)
HOXA11Homeobox protein Hox-A11. (314 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase MLT isoform 1. (800 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
GLI3GLI family zinc finger 3. (1578 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
WDPCPWD repeat containing planar cell polarity effector. (738 aa)
RSPO2R-spondin-2. (243 aa)
CRABP2Cellular retinoic acid-binding protein 2; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (138 aa)
BCL2L11BCL2 like 11. (249 aa)
LMBR1Limb development membrane protein 1; Belongs to the LIMR family. (529 aa)
FUZFuzzy planar cell polarity protein. (418 aa)
RARBRetinoic acid receptor beta isoform 1. (448 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
INTUInturned planar cell polarity protein. (942 aa)
SKISKI proto-oncogene. (729 aa)
TBC1D32TBC1 domain family member 32. (1297 aa)
PBX2PBX homeobox 2. (431 aa)
SALL1Spalt like transcription factor 1. (1322 aa)
RPGRIP1LRPGRIP1 like. (1268 aa)
TBX4T-box transcription factor TBX4. (545 aa)
TBX2T-box transcription factor 2. (713 aa)
SP8Sp8 transcription factor. (507 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2173 aa)
WDR19WD repeat domain 19. (1342 aa)
SALL4Uncharacterized protein. (986 aa)
DLX5Distal-less homeobox 5. (289 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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