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DKK1 DKK1 ENSCJAP00000075867 ENSCJAP00000075867 VWC2 VWC2 HTRA1 HTRA1 SKOR1 SKOR1 HTRA4 HTRA4 CTDSPL2 CTDSPL2 SKI SKI TNFAIP6 TNFAIP6 DAND5 DAND5 GDF3 GDF3 LRP2 LRP2 NBL1 NBL1 SORL1 SORL1 WNT5A WNT5A NOTCH1 NOTCH1 SFRP1 SFRP1 VWC2L VWC2L BMPER BMPER CER1 CER1 TRIM33 TRIM33 FSTL3 FSTL3 BAMBI BAMBI HIPK2 HIPK2 LEMD3 LEMD3 CHRD CHRD CHRDL2 CHRDL2 SPG20 SPG20 PPM1A PPM1A WNT1 WNT1 FBN1 FBN1 LEMD2 LEMD2 SFRP2 SFRP2 UBE2D1 UBE2D1 NOG NOG SMURF1 SMURF1 SKOR2 SKOR2 SMAD6 SMAD6 GREM2 GREM2 HJV HJV SMURF2 SMURF2 CHRDL1 CHRDL1 SOSTDC1 SOSTDC1 DLX1 DLX1 SMAD7 SMAD7 ABL1 ABL1 CRIM1 CRIM1 TMPRSS6 TMPRSS6 TWSG1 TWSG1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DKK1Dickkopf_N domain-containing protein. (332 aa)
ENSCJAP00000075867Sclerostin. (213 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
HTRA1HtrA serine peptidase 1. (522 aa)
SKOR1SKI family transcriptional corepressor 1. (966 aa)
HTRA4HtrA serine peptidase 4. (476 aa)
CTDSPL2CTD small phosphatase-like protein 2. (466 aa)
SKISKI proto-oncogene. (729 aa)
TNFAIP6Tumor necrosis factor-inducible gene 6 protein. (277 aa)
DAND5DAN domain BMP antagonist family member 5. (189 aa)
GDF3Growth differentiation factor 3. (364 aa)
LRP2LDL receptor related protein 2. (4656 aa)
NBL1NBL1, DAN family BMP antagonist. (216 aa)
SORL1Sortilin related receptor 1. (2307 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
NOTCH1Notch receptor 1. (2551 aa)
SFRP1Secreted frizzled-related protein 1. (314 aa)
VWC2LVon Willebrand factor C domain containing 2 like. (219 aa)
BMPERBMP binding endothelial regulator. (686 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
TRIM33E3 ubiquitin-protein ligase TRIM33 isoform alpha. (1127 aa)
FSTL3Follistatin like 3. (267 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
HIPK2Homeodomain-interacting protein kinase 2 isoform 1. (1196 aa)
LEMD3Inner nuclear membrane protein Man1 isoform 1. (911 aa)
CHRDChordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (967 aa)
CHRDL2Chordin like 2. (452 aa)
SPG20Spartin. (666 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
FBN1Fibrillin 1. (3018 aa)
LEMD2LEM domain containing 2. (542 aa)
SFRP2Secreted frizzled related protein 2. (538 aa)
UBE2D1Ubiquitin conjugating enzyme E2 D1; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
SMURF1E3 ubiquitin-protein ligase. (757 aa)
SKOR2SKI family transcriptional corepressor 2. (1013 aa)
SMAD6Mothers against decapentaplegic homolog. (498 aa)
GREM2Gremlin. (168 aa)
HJVHemojuvelin BMP co-receptor. (422 aa)
SMURF2E3 ubiquitin-protein ligase. (748 aa)
CHRDL1Chordin-like protein 1 isoform 1. (458 aa)
SOSTDC1CTCK domain-containing protein. (230 aa)
DLX1Homeobox protein DLX-1 isoform 1. (255 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
CRIM1Cysteine rich transmembrane BMP regulator 1. (1036 aa)
TMPRSS6Transmembrane serine protease 6; Belongs to the peptidase S1 family. (709 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (219 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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