STRINGSTRING
CTNS CTNS HOXD9 HOXD9 OPRD1 OPRD1 NCSTN NCSTN NLGN3 NLGN3 GIP GIP PPT1 PPT1 DRD3 DRD3 ATP6V1B1 ATP6V1B1 NTF4 NTF4 F7GPP2_CALJA F7GPP2_CALJA SLITRK1 SLITRK1 NPC1 NPC1 INPP5F INPP5F GBX1 GBX1 CDK5 CDK5 CRHBP CRHBP F7GME1_CALJA F7GME1_CALJA SDK1 SDK1 UNC79 UNC79 HEXA HEXA ASIP ASIP MAFG MAFG BBS4 BBS4 TSC1 TSC1 LEP LEP ABAT ABAT CNTN2 CNTN2 TSHR TSHR NRXN2 NRXN2 GHRL GHRL NLGN2 NLGN2 CXCL12 CXCL12 AGRP AGRP HOMER2 HOMER2 RNF180 RNF180 GLRA1 GLRA1 CHL1 CHL1 CNP CNP AGTPBP1 AGTPBP1 SPTBN4 SPTBN4 MECP2 MECP2 ADAM22 ADAM22 F7HQY5_CALJA F7HQY5_CALJA APP APP GIGYF2 GIGYF2 SEZ6 SEZ6 HIPK2 HIPK2 TPGS1 TPGS1 OPRM1 OPRM1 PAFAH1B1 PAFAH1B1 DRD2 DRD2 EPHA4 EPHA4 DRD4 DRD4 CEND1 CEND1 ABHD12 ABHD12 SLC1A1 SLC1A1 TMOD1 TMOD1 LGI4 LGI4 KLHL4 KLHL4 CHRNB4 CHRNB4 PAX5 PAX5 CHRNA3 CHRNA3 CHRNA5 CHRNA5 DBH DBH CNTNAP2 CNTNAP2 CHRNB2 CHRNB2 OTOG OTOG CHD7 CHD7 ALK ALK HOXD10 HOXD10 ZFHX2 ZFHX2 HOMER1 HOMER1 PBX3 PBX3 OXR1 OXR1 PUM1 PUM1 FOXA2 FOXA2 GRM2 GRM2 PPP1R1B PPP1R1B PREX2 PREX2 CLN8 CLN8 SLC7A11 SLC7A11 SLITRK5 SLITRK5 SLITRK6 SLITRK6 ZMPSTE24 ZMPSTE24 EHMT2 EHMT2 GHSR GHSR CCND2 CCND2 BBS1 BBS1 SPTBN2 SPTBN2 SHANK2 SHANK2 FADD FADD H9KVM9_CALJA H9KVM9_CALJA KLHL1 KLHL1 CHRNB1 CHRNB1 GRIN2D GRIN2D PARK7 PARK7 PPARA PPARA SCN1A SCN1A PTEN PTEN EN1 EN1 ENSCJAP00000055015 ENSCJAP00000055015 SHANK1 SHANK1 ENSCJAP00000055790 ENSCJAP00000055790 CARTPT CARTPT ENSCJAP00000058431 ENSCJAP00000058431 HOXB8 HOXB8 LOC100402272 LOC100402272 ENSCJAP00000060287 ENSCJAP00000060287 CHRNA4 CHRNA4 NR4A2 NR4A2 LOC100404734 LOC100404734 SEZ6L2 SEZ6L2 KALRN KALRN BTBD9 BTBD9 NRXN3 NRXN3 NTSR1 NTSR1 NRXN1 NRXN1 NTAN1 NTAN1 ENSCJAP00000065208 ENSCJAP00000065208 EFNB3 EFNB3 TRH TRH CSTB CSTB ZIC1 ZIC1 DMRT3 DMRT3 ENSCJAP00000069145 ENSCJAP00000069145 ENSCJAP00000069474 ENSCJAP00000069474 DMBX1 DMBX1 ENSCJAP00000070238 ENSCJAP00000070238 CRHR1 CRHR1 FGF12 FGF12 PCDH17 PCDH17 PRKN PRKN SHANK3 SHANK3 EPS8 EPS8 FXN FXN ENSCJAP00000073407 ENSCJAP00000073407 ENSCJAP00000073449 ENSCJAP00000073449 PCDH15 PCDH15 KLHL5 KLHL5 CACNB4 CACNB4 HDAC2 HDAC2 GLRB GLRB SLC1A2 SLC1A2 ENSCJAP00000075918 ENSCJAP00000075918 BBS2 BBS2 SEPTIN5 SEPTIN5 ENSCJAP00000078157 ENSCJAP00000078157 SNCG SNCG HTRA2 HTRA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CTNSCystinosin, lysosomal cystine transporter. (400 aa)
HOXD9Homeobox D9. (342 aa)
OPRD1Delta-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (372 aa)
NCSTNNicastrin. (825 aa)
NLGN3Neuroligin-3 isoform 1. (848 aa)
GIPGastric inhibitory polypeptide. (153 aa)
PPT1Palmitoyl-protein thioesterase 1. (306 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (400 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
NTF4Neurotrophin-4 preproprotein; Belongs to the NGF-beta family. (210 aa)
F7GPP2_CALJACystatin domain-containing protein; Belongs to the cystatin family. (98 aa)
SLITRK1SLIT and NTRK like family member 1. (696 aa)
NPC1NPC intracellular cholesterol transporter 1. (1277 aa)
INPP5FPhosphatidylinositide phosphatase SAC2 isoform 1. (1132 aa)
GBX1Gastrulation brain homeobox 1. (362 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (306 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (322 aa)
F7GME1_CALJAUncharacterized protein. (594 aa)
SDK1Sidekick cell adhesion molecule 1. (2214 aa)
UNC79Unc-79 homolog, NALCN channel complex subunit. (2653 aa)
HEXABeta-hexosaminidase. (529 aa)
ASIPAgouti-signaling protein; Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment) (By similarity). (132 aa)
MAFGMAF bZIP transcription factor G. (162 aa)
BBS4Bardet-Biedl syndrome 4. (518 aa)
TSC1Hamartin isoform 3. (1168 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (542 aa)
CNTN2Contactin-2. (1040 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
NRXN2Neurexin 2. (1715 aa)
GHRLAppetite-regulating hormone isoform 1 preproprotein. (117 aa)
NLGN2Neuroligin 2. (838 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
AGRPAgouti related neuropeptide. (132 aa)
HOMER2Homer scaffold protein 2. (359 aa)
RNF180Ring finger protein 180. (592 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
CHL1Neural cell adhesion molecule L1-like protein isoform 1. (1225 aa)
CNP2',3'-cyclic-nucleotide 3'-phosphodiesterase; May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin; Belongs to the 2H phosphoesterase superfamily. CNPase family. (421 aa)
AGTPBP1ATP/GTP binding protein 1. (1275 aa)
SPTBN4Spectrin beta chain, non-erythrocytic 4 isoform sigma5. (678 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (497 aa)
ADAM22Disintegrin and metalloproteinase domain-containing protein 22 isoform 1 preproprotein. (906 aa)
F7HQY5_CALJAFibroblast growth factor; Belongs to the heparin-binding growth factors family. (116 aa)
APPAmyloid beta A4 protein isoform a. (770 aa)
GIGYF2PERQ amino acid-rich with GYF domain-containing protein 2 isoform b. (1296 aa)
SEZ6Seizure protein 6 homolog isoform 1. (994 aa)
HIPK2Homeodomain-interacting protein kinase 2 isoform 1. (1196 aa)
TPGS1Tubulin polyglutamylase complex subunit 1. (302 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (473 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
DRD2D(2) dopamine receptor isoform long; Belongs to the G-protein coupled receptor 1 family. (443 aa)
EPHA4Ephrin type-A receptor 4. (986 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (392 aa)
CEND1Cell cycle exit and neuronal differentiation protein 1. (144 aa)
ABHD12Monoacylglycerol lipase ABHD12 isoform a. (398 aa)
SLC1A1Excitatory amino acid transporter 3. (524 aa)
TMOD1Tropomodulin 1. (359 aa)
LGI4Leucine-rich repeat LGI family member 4. (538 aa)
KLHL4Kelch like family member 4. (719 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (492 aa)
PAX5Paired box 5. (393 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (503 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (469 aa)
DBHDopamine beta-hydroxylase. (621 aa)
CNTNAP2Contactin associated protein like 2. (1331 aa)
CHRNB2Neuronal acetylcholine receptor subunit beta-2. (502 aa)
OTOGOtogelin. (2908 aa)
CHD7Chromodomain-helicase-DNA-binding protein 7. (2994 aa)
ALKTyrosine-protein kinase receptor. (1621 aa)
HOXD10Homeobox protein Hox-D10. (340 aa)
ZFHX2Zinc finger homeobox 2. (2570 aa)
HOMER1Homer scaffold protein 1. (354 aa)
PBX3Pre-B-cell leukemia transcription factor 3 isoform 1. (434 aa)
OXR1Oxidation resistance 1. (883 aa)
PUM1Pumilio RNA binding family member 1. (1226 aa)
FOXA2Forkhead box A2. (456 aa)
GRM2Metabotropic glutamate receptor 2 isoform a. (872 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (201 aa)
PREX2Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2. (1592 aa)
CLN8CLN8 transmembrane ER and ERGIC protein. (287 aa)
SLC7A11Cystine/glutamate transporter. (501 aa)
SLITRK5SLIT and NTRK like family member 5. (957 aa)
SLITRK6SLIT and NTRK like family member 6. (840 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
EHMT2Euchromatic histone lysine methyltransferase 2. (1268 aa)
GHSRGhrelin receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
CCND2G1/S-specific cyclin-D2; Belongs to the cyclin family. (289 aa)
BBS1BBS1 domain-containing protein. (593 aa)
SPTBN2Spectrin beta chain; Belongs to the spectrin family. (2394 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1794 aa)
FADDFas associated via death domain. (284 aa)
H9KVM9_CALJAANF_receptor domain-containing protein. (267 aa)
KLHL1Kelch-like protein 1. (748 aa)
CHRNB1Cholinergic receptor nicotinic beta 1 subunit. (501 aa)
GRIN2DGlutamate ionotropic receptor NMDA type subunit 2D. (1336 aa)
PARK7Protein DJ-1. (189 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (468 aa)
SCN1ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2009 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
EN1Homeobox protein engrailed-like. (391 aa)
ENSCJAP00000055015Cystatin domain-containing protein; Belongs to the cystatin family. (98 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (2169 aa)
ENSCJAP00000055790Cystatin domain-containing protein; Belongs to the cystatin family. (98 aa)
CARTPTCocaine-and amphetamine-regulated transcript protein preproprotein. (116 aa)
ENSCJAP00000058431Cystatin domain-containing protein; Belongs to the cystatin family. (98 aa)
HOXB8Homeobox B8. (243 aa)
LOC100402272Cystatin domain-containing protein; Belongs to the cystatin family. (98 aa)
ENSCJAP00000060287DJ-1_PfpI domain-containing protein. (143 aa)
CHRNA4Cholinergic receptor nicotinic alpha 4 subunit. (640 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (598 aa)
LOC100404734Cystatin domain-containing protein; Belongs to the cystatin family. (98 aa)
SEZ6L2Seizure related 6 homolog like 2. (956 aa)
KALRNKalirin RhoGEF kinase. (2986 aa)
BTBD9BTB/POZ domain-containing protein 9 isoform a. (612 aa)
NRXN3Neurexin 3. (1664 aa)
NTSR1Neurotensin receptor 1; Belongs to the G-protein coupled receptor 1 family. (609 aa)
NRXN1Neurexin 1. (1507 aa)
NTAN1N-terminal asparagine amidase. (394 aa)
ENSCJAP00000065208DJ-1_PfpI domain-containing protein. (153 aa)
EFNB3Ephrin-B3; Belongs to the ephrin family. (340 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (242 aa)
CSTBCystatin-B; Belongs to the cystatin family. (98 aa)
ZIC1Zic family member 1. (450 aa)
DMRT3DM domain-containing protein. (472 aa)
ENSCJAP00000069145G_PROTEIN_RECEP_F2_4 domain-containing protein. (283 aa)
ENSCJAP00000069474G_PROTEIN_RECEP_F2_3 domain-containing protein. (120 aa)
DMBX1Diencephalon/mesencephalon homeobox 1. (378 aa)
ENSCJAP00000070238Uncharacterized protein. (124 aa)
CRHR1G_PROTEIN_RECEP_F2_4 domain-containing protein. (283 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
PCDH17Protocadherin 17. (1187 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (476 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1897 aa)
EPS8Epidermal growth factor receptor pathway substrate 8. (839 aa)
FXNFrataxin, mitochondrial isoform 1 preproprotein. (213 aa)
ENSCJAP00000073407Uncharacterized protein. (101 aa)
ENSCJAP00000073449DJ-1_PfpI domain-containing protein. (83 aa)
PCDH15Protocadherin related 15. (1951 aa)
KLHL5Kelch like family member 5. (777 aa)
CACNB4Voltage-dependent L-type calcium channel subunit beta-4 isoform c. (502 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (491 aa)
GLRBGlycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (555 aa)
SLC1A2Amino acid transporter. (603 aa)
ENSCJAP00000075918Protein kinase domain-containing protein. (253 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (738 aa)
SEPTIN5Septin 5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (515 aa)
ENSCJAP00000078157DJ-1_PfpI domain-containing protein. (148 aa)
SNCGGamma-synuclein; Belongs to the synuclein family. (201 aa)
HTRA2HtrA serine peptidase 2. (584 aa)
Your Current Organism:
Callithrix jacchus
NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset
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