(30 nodes) Response to testosterone network (Callithrix jacchus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSCJAP00000069314	ARA70 domain-containing protein. (105 aa)
	THBS1	Thrombospondin 1. (1178 aa)
	ENSCJAP00000072850	Homeobox domain-containing protein. (229 aa)
	XRN1	5'-3' exoribonuclease 1. (1707 aa)
	AR	Androgen receptor. (887 aa)
	MSN	Moesin. (681 aa)
	RWDD1	RWD domain-containing protein 1 isoform a. (243 aa)
	SPP1	Secreted phosphoprotein 1. (321 aa)
	TBXA2R	Thromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (407 aa)
	CBL	E3 ubiquitin-protein ligase CBL. (909 aa)
	NASP	Uncharacterized protein. (775 aa)
	FOXP1	Fork-head domain-containing protein. (693 aa)
	ELK1	ETS transcription factor ELK1. (479 aa)
	CA9	Carbonic anhydrase 9; Belongs to the alpha-carbonic anhydrase family. (453 aa)
	HOXA11	Homeobox protein Hox-A11. (314 aa)
	HOXB13	Homeobox protein Hox-B13. (284 aa)
	AVP	Arginine vasopressin; Belongs to the vasopressin/oxytocin family. (211 aa)
	ROCK2	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1388 aa)
	HMGCS2	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1366 aa)
	ENSCJAP00000039892	Heat shock transcription factor 1. (557 aa)
	RPS6KB1	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (525 aa)
	HOXD13	Homeobox protein Hox-D13. (344 aa)
	HOXA13	Homeobox A13. (385 aa)
	NKX3-1	NK3 homeobox 1. (286 aa)
	HOXA10	Homeobox domain-containing protein. (94 aa)
	ENSCJAP00000077152	RWD domain-containing protein. (130 aa)
	ENSCJAP00000067952	Uncharacterized protein. (87 aa)
	BAD	Bcl2 antagonist of cell death. (167 aa)
	TSPO	Translocator protein. (203 aa)

Your Current Organism:

Callithrix jacchus

NCBI taxonomy Id: 9483
Other names: C. jacchus, Callithrix jacchus jacchus, common marmoset, white ear-tufted marmoset, white-tufted-ear marmoset

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AR	ENSCJAP00000067952	ENSCJAP00000006494	ENSCJAP00000067952	Androgen receptor.	Uncharacterized protein.	0.881
AR	ENSCJAP00000069314	ENSCJAP00000006494	ENSCJAP00000069314	Androgen receptor.	ARA70 domain-containing protein.	0.881
AR	HOXB13	ENSCJAP00000006494	ENSCJAP00000013827	Androgen receptor.	Homeobox protein Hox-B13.	0.531
AR	IGF1R	ENSCJAP00000006494	ENSCJAP00000011684	Androgen receptor.	Tyrosine-protein kinase receptor.	0.601
AR	NKX3-1	ENSCJAP00000006494	ENSCJAP00000067787	Androgen receptor.	NK3 homeobox 1.	0.606
CBL	IGF1R	ENSCJAP00000025794	ENSCJAP00000011684	E3 ubiquitin-protein ligase CBL.	Tyrosine-protein kinase receptor.	0.801
ENSCJAP00000067952	AR	ENSCJAP00000067952	ENSCJAP00000006494	Uncharacterized protein.	Androgen receptor.	0.881
ENSCJAP00000069314	AR	ENSCJAP00000069314	ENSCJAP00000006494	ARA70 domain-containing protein.	Androgen receptor.	0.881
HOXA10	HOXA11	ENSCJAP00000034949	ENSCJAP00000015124	Homeobox domain-containing protein.	Homeobox protein Hox-A11.	0.658
HOXA11	HOXA10	ENSCJAP00000015124	ENSCJAP00000034949	Homeobox protein Hox-A11.	Homeobox domain-containing protein.	0.658
HOXA11	HOXA13	ENSCJAP00000015124	ENSCJAP00000062794	Homeobox protein Hox-A11.	Homeobox A13.	0.433
HOXA13	HOXA11	ENSCJAP00000062794	ENSCJAP00000015124	Homeobox A13.	Homeobox protein Hox-A11.	0.433
HOXB13	AR	ENSCJAP00000013827	ENSCJAP00000006494	Homeobox protein Hox-B13.	Androgen receptor.	0.531
IGF1R	AR	ENSCJAP00000011684	ENSCJAP00000006494	Tyrosine-protein kinase receptor.	Androgen receptor.	0.601
IGF1R	CBL	ENSCJAP00000011684	ENSCJAP00000025794	Tyrosine-protein kinase receptor.	E3 ubiquitin-protein ligase CBL.	0.801
IGF1R	RPS6KB1	ENSCJAP00000011684	ENSCJAP00000048517	Tyrosine-protein kinase receptor.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.406
MSN	ROCK2	ENSCJAP00000006842	ENSCJAP00000038079	Moesin.	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	0.577
NKX3-1	AR	ENSCJAP00000067787	ENSCJAP00000006494	NK3 homeobox 1.	Androgen receptor.	0.606
ROCK2	MSN	ENSCJAP00000038079	ENSCJAP00000006842	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.	Moesin.	0.577
RPS6KB1	IGF1R	ENSCJAP00000048517	ENSCJAP00000011684	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	Tyrosine-protein kinase receptor.	0.406